Plasma leptin in chronic fatigue syndrome and a placebo-controlled study of the effects of low-dose hydrocortisone on leptin secretion

Clinical Endocrinology

Volumn 55, Issue 1, 2001, Pages 113-119

  Cleare, A J ^a,b   O'Keane, V ^c   Miell, J ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c CAMBRIDGE UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; LEPTIN;

ADULT; ARTICLE; CHRONIC FATIGUE SYNDROME; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DISEASE MARKER; DOSE RESPONSE; DRUG EFFECT; FEMALE; HUMAN; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN METABOLISM; PROTEIN SECRETION; RANDOMIZED CONTROLLED TRIAL; RECEPTOR SENSITIVITY; TREATMENT OUTCOME;

ADULT; ANTI-INFLAMMATORY AGENTS; BIOLOGICAL MARKERS; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; FATIGUE SYNDROME, CHRONIC; FEMALE; HUMANS; HYDROCORTISONE; LEPTIN; MALE; MIDDLE AGED; TREATMENT OUTCOME;

EID: 0035726374     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.2001.01341.x     Document Type: Article

References (45)

1. Evidence for a novel peripheral action of leptin as a metabolic signal to the adrenal gland: Leptin inhibits cortisol release directly
2. Development of a fatigue scale
3. The neuroendocrinology of depression and chronic stress
4. Plasma leptin levels do not change in patients with Cushing's disease shortly after correction of hypercortisolism
5. Neurochemistry
6. Low-dose hydrocortisone in chronic fatigue syndrome: A randomised crossover trial
7. Hypothalamo-pituitary-adrenal axis dysfunction in chronic fatigue syndrome, and the effects of low-dose hydro-cortisone therapy
8. Serum immunoreactive-leptin concentrations in normal-weight and obese humans
9. Dexamethasone stimulates leptin release from human adipocytes: Unexpected inhibition by insulin
10. Robust leptin secretory responses to dexamethasone in obese subjects
11. Evidence for and pathophysiologic implications of hypothalamic-pituitary-adrenal axis dysregulation in fibromyalgia and chronic fatigue syndrome
12. The chronic fatigue syndrome: A comprehensive approach to its definition and study
13. Leptin concentrations, sex hormones, and cortisol in nondiabetic men
14. Multihormonal control of ob gene expression and leptin secretion from cultured human visceral adipose tissue: Increased responsiveness to glucocorticoids in obesity
15. Gender differences in plasma leptin concentrations
16. Leptin inhibition of the hypothalamicpituitary-adrenal axis in response to stress
17. Feeding and body weight regulation by hypothalamic neuropeptides - Mediation of the actions of leptin
18. Leptin levels do not change acutely with food administration in normal or obese subjects, but are negatively correlated with pituitary-adrenal activity
19. Short-term dexamethasone treatment increases plasma leptin independently of changes in insulin sensitivity in healthy women
20. Short-term night-shift working mimics the pituitary-adrenocortical dysfunction of chronic fatigue syndrome
21. Human leptin levels are pulsatile and inversely related to pituitary-adrenal function
22. The obese gene and its product leptin - A new route towards obesity treatment in man
23. Low-dose hydrocortisone treatment of chronic fatigue syndrome: Results of a placebo controlled study of its efficacy and safety
24. Dexamethasone induces an acute and sustained rise in circulating leptin levels in normal human subjects
25. Dose-dependent cortisol-induced increases in plasma leptin concentration in healthy humans
26. Dexamethasone increases leptin expression in humans in vivo
27. Biological markers in CFS and neurasthenia
28. Levels of leptin during hydrocortisone infusions that mimic normal and reversed diurnal cortisol levels in subjects with adrenal insufficiency
29. Identification of targets of leptin action in rat hypothalamus
30. The neuroendocrinology of chronic fatigue syndrome: Focus on the hypothalamic-pituitary-adrenal axis
31. Chronic fatigue syndrome: Guidelines for research
32. Chronic fatigue syndrome. A practical guide to assessment and management
33. Leptin increases hypothalamic POMC mRNA expression in the rostral arcuate nucleus
34. The MOS Short-form General Health Survey: Reliability and validity in a patient population
35. Chronic fatigue syndrome and seasonal affective disorder: Comorbidity, diagnostic overlap, and implications for treatment
36. The effects of glucocorticoids on leptin levels in humans may be restricted to acute pharmacologic dosing
37. CD4 T lymphocytes from patients with chronic fatigue syndrome have decreased interferon-gamma production and increased sensitivity to dexamethasone
38. Determinants of serum leptin levels in Cushing's syndrome
39. Somatic discomforts among depressed women
40. Positional cloning of the mouse obese gene and its human homolog