The significance of immune responses to allergens in early life

Clinical and Experimental Allergy

Volumn 31, Issue 8, 2001, Pages 1167-1169

  Prescott, S L ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; CYTOKINE; FOOD ALLERGEN; GAMMA INTERFERON;

ALLERGIC DISEASE; ANTIGEN PRESENTING CELL; ATOPY; BIRTH DEFECT; CELL ACTIVATION; CELL DIFFERENTIATION; CELL POPULATION; CROSS REACTION; DERMATOPHAGOIDES PTERONYSSINUS; EDITORIAL; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL FACTOR; FETOMATERNAL TRANSFUSION; FETUS CIRCULATION; HIGH RISK POPULATION; HUMAN; IMMATURITY; IMMUNE RESPONSE; MONONUCLEAR CELL; PATHOGENESIS; POSTNATAL DEVELOPMENT; PREGNANCY; PRIORITY JOURNAL; PROPHYLAXIS; SIGNAL TRANSDUCTION; TH1 CELL; TH2 CELL; UMBILICAL CORD BLOOD;

AGING; ALLERGENS; HUMANS; INFANT; INFANT, NEWBORN;

EID: 0035726112     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2222.2001.01172.x     Document Type: Editorial

References (31)

1. Heterogeneity of cytokine secretion patterns and functions of helper T cells
2. Human Th1 and Th2 subsets: Doubt no more
3. Interferonγ production by cord blood mononuclear cells is reduced in newborns with a family history of atopic disease and is independant from cord blood IgE levels
4. Reduced interferon gamma secretion in neonates and subsequent atopy
5. Decreased production of IFNγ and decreased production of IL-6 by cord blood mononuclear cells of newborns with a high risk of allergy
6. Prenatal allergen contact with milk proteins
7. Reciprocal age-related patterns of allergen-specific T-cell immunity in normal vs. atopic infants
8. Effects of maternal allergen-specific IgG in cord blood on early postnatal development of allergen-specific T-cell immunity
9. Genetic 'risk' for atopy is associated with delayed postnatal maturation of T cell competence
10. Development of sensitization versus tolerance to inhalant allergens during early life
11. Development of allergen-specific T-cell memory in atopic and normal children
12. Bidirectional cytokine interactions in the maternal-fetal relationship: Is successful pregnancy a Th2 phenomenon?
13. Neonates at risk of atopy show impaired production of interferon-gamma after stimulation with bacterial products (LPS and SEE)
14. Neonatal tolerance revisited. Turning on newborn T cells with dendritic cells
15. Fetal and neonatal IL-13 production during pregnancy and at birth and subsequent development of atopic symptoms
16. Transplacental priming of the human immune system to environmental allergens: Universal skewing of initial T-cell responses towards Th-2 cytokine profile
17. Reduced expression of hemopoietic cytokine receptors on cord blood progenitor cells in neonates at risk for atopy
18. Editorial: Is allergic disease programmed in early life?
19. Lymphoproliferative responses in cord blood and at one year: No evidence for the effect of in utero exposure to dust mite allergens
20. Differences in antigen-specific T-cell responses between infants with atopic dermatitis with and without cow's milk allergy: Relevance of TH2 cytokines
21. Cord blood lymphocyte responses to food antigens for the prediction of allergic disorders
22. Reduced interferon gamma production by antigen-stimulated cord blood mononuclear cells is a risk factor of allergic disorders - 6-year follow-up study
23. Is deficiency of interferon gamma production by allergen triggered cord blood cells a predictor of atopic eczema?
24. Cord blood mononuclear cell responsiveness to beta-lactoglobulin: T-cell acitivity in 'atopy-prone' and 'non-atopy-prone' newborns
25. The passage of orally fed proteins from mother to foetus in the rat
26. Direct evidence for transplacental allergen transfer
27. Aeroallergen sensitization can occur during fetal life
28. Fetal peripheral blood mononuclear cell proliferative responses to mitogenic and allergenic stimuli during gestation
29. Cord blood proliferative responses to inhaled allergens: Is there a phenomenon?
30. Inhalant allergen-specific T-cell reactivity is detectable in close to 100% of atopic and normal individuals: Covert responses are unmasked by serum-free medium
31. Maternal antigen avoidance during pregnancy for preventing atopic disease in infants of women at high risk