Selective expression of FLIP in malignant melanocytic skin lesions

Journal of Investigative Dermatology

Volumn 117, Issue 2, 2001, Pages 360-364

  Bullani, Roberto R ^a   Huard, Bertrand ^a   Viard Leveugle, Isabelle ^a   Byers, H Randolph ^b   Irmler, Martin ^c   Saurat, Jean Hilaire ^a   Tschopp, Jürg ^c   French, Lars E ^a  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Apoptosis; Death receptors; Melanoma

Indexed keywords

FAS ANTIGEN; FAS LIGAND; FLICE INHIBITORY PROTEIN; PROTEIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

ARTICLE; BENIGN TUMOR; CELL DEATH; CELL LINE; CONTROLLED STUDY; DISEASE ASSOCIATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MELANOCYTE; MELANOMA; MELANOMA CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SKIN CARCINOMA;

EID: 0035720569     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0022-202X.2001.01418.x     Document Type: Article

References (33)

1. Apoptosis control by death and decoy receptors
2. Death receptors: Signaling and modulation
3. Down-regulation of Fas gene expression in colon cancer is not a result of allelic loss or gene rearrangement
4. Cell migration and actin organization in cultured human primary, recurrent cutaneous and metastatic melanoma. Time-lapse and image analysis
5. The inhibitor of death receptor signaling, FLICE-inhibitory protein defines a new class of tumor progression factors
6. Human dendritic cells mediate cellular apoptosis via tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)
7. CASH, a novel caspase homologue with death effector domains
8. Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells
9. Monocyte-mediated tumoricidal activity via the tumor necrosis factor-related cytokine, TRAIL
10. I-FLICE a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis
11. Inhibition of death receptor signals by cellular FLIP
12. Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
13. Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity
14. Involvement of TNF-related apoptosis-inducing ligand in human CD4+ T cell-mediated cytotoxicity
15. Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells
16. Decreased Fas antigen receptor expression in testicular tumor cell lines derived from polyomavirus large T-antigen transgenic mice
17. A null mutation in the perforin gene impairs cytolytic T lymphocyte- and natural killer cell- mediated cytotoxicity
18. Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways
19. Immune escape of tumors in vivo by expression of cellular FLICE- inhibitory protein
20. Expression of APO-1 (CD95), a member of the NGF/TNF receptor superfamily, in normal and neoplastic colon epithelium
21. Apoptosis by death factor
22. Oncogenic Ras inhibits Fas ligand-mediated apoptosis by downregulating the expression of Fas
23. Cell death attenuation by "Usurpin", a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex
24. Functional consequences of APO-1/Fas (CD95) antigen expression by normal and neoplastic hematopoietic cells
25. Fas-dependent tissue turnover is implicated in tumor cell clearance
26. Lymhocyte apoptosis induced by CD95 (Apo-1/Fas) ligand-expressing tumor cells-A mechanism of immune evasion?
27. TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis in Fas ligand-resistant melanoma cells and mediates CD 4 T cell killing of target cells
28. Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
29. Heterogenous susceptibility to CD95-induced apoptosis in melanoma cells correlates with bcl-2 and bcl-x expression and is sensitive to modulation by interferon-gamma
30. Expression of c-FLIP (L) and resistance to CD95-mediated apoptosis of monocyte-derived dendritic cells: Inhibition by bisindolylmaleimide
31. Natural killer (NK) cell-mediated cytotoxicity: Differential use of TRAIL and Fas ligand by immature and mature primary human NK cells
32. Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma
33. Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases