Designing gene therapy vectors: Avoiding immune responses by using tissue-specific promoters

Gene Therapy

Volumn 8, Issue 24, 2001, Pages 1872-1878

  Weeratna, R D ^a   Wu, T ^a   Efler, S M ^a   Zhang, L ^a   Davis, H L ^a  

^a Coley Pharmaceutical Canada ^*  (Canada)

Author keywords

DNA vaccines; Gene therapy applications; Tissue specific promoters

Indexed keywords

CREATINE KINASE; DNA VACCINE; GENE PRODUCT; HEPATITIS B SURFACE ANTIGEN; KANAMYCIN; PENICILLIN G; PLASMID DNA; STREPTOMYCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ANTIGEN SPECIFICITY; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOMEGALOVIRUS; DNA VECTOR; DRUG DESIGN; ENZYME SPECIFICITY; GENE THERAPY; GENETIC CODE; GENETIC DISORDER; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; LYMPH NODE; LYMPHATIC DRAINAGE; MOLECULAR STABILITY; MOUSE; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; TISSUE SPECIFICITY; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY;

ANIMALS; ANTIGEN-PRESENTING CELLS; CREATINE KINASE; CYTOMEGALOVIRUS; FEMALE; GENE THERAPY; GENETIC VECTORS; HUMANS; INJECTIONS, INTRAMUSCULAR; MICE; MICE, INBRED BALB C; MUSCLE, SKELETAL; PROMOTER REGIONS (GENETICS); VACCINES, DNA;

ANIMALIA; CYTOMEGALOVIRUS; DNA VIRUSES;

EID: 0035713273     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301602     Document Type: Article

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