Induction of cytotoxic CD8+CD56+ T cells from human thymocytes by interleukin-15

Journal of Interferon and Cytokine Research

Volumn 21, Issue 11, 2001, Pages 905-911

  Thulesen, S ^a   Nissen, M H ^a   Odum N ^a   Ropke C ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 15; INTERLEUKIN 2;

ARTICLE; CELL CULTURE; CELL GROWTH; CELL ISOLATION; CELL MATURATION; CHILD; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN CELL; IMMUNOLOGICAL MEMORY; INFANT; LYMPHOCYTE COUNT; PERIPHERAL LYMPHOCYTE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; THYMOCYTE;

ANTIGENS, CD56; BLOOD; CELLS, CULTURED; CYTOTOXICITY TESTS, IMMUNOLOGIC; HUMANS; IMMUNOLOGIC MEMORY; IMMUNOPHENOTYPING; INTERLEUKIN-12; INTERLEUKIN-15; RECEPTORS, INTERLEUKIN-15; RECEPTORS, INTERLEUKIN-2; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, CYTOTOXIC; THYMUS GLAND;

EID: 0035677039     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/107999001753289514     Document Type: Article

References (35)

1. + natural T cells with distinct cytotoxic activities and Th1, Th2, and Th0 cytokine secretion patterns
2. + T cells closely correlates with CD56 surface expression
3. Molecular and functional analysis of human natural killer cell-associated neural cell adhesion molecule (N-CAM/CD56)
4. Interleukin 15 is a growth factor for human thymocytes with preferential effect on CD8(+) cells
5. Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15
6. Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor
7. The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens
8. Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor
9. The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells
10. Cytokines: Shared receptors, distinct functions
11. + T cells in vivo by IL-15
12. Differential effects of interleukin-15 and interleukin-2 on differentiation of bipotential T/natural killer progenitor cells
13. Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor
14. IL-15: A pleiotropic cytokine with diverse receptor/signaling pathways whose expression is controlled at multiple levels
15. Chemoattraction of human blood T lymphocytes by interleukin-15
16. Interleukin-2, interleukin-15, and their receptors
17. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation
18. Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment
19. Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice
20. IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice
21. Super-antigens are presented by and activate thymocytes from infants
22. + T cells
23. - human T cells
24. CD56 directly interacts in the process of NCAM-positive target cell killing by NK cells
25. Interleukin (IL)-15 enhances antibody-dependent cellular cytotoxicity and natural killer activity in neonatal cells
26. IL-15 and IL-2: A matter of life and death for T cells in vivo
27. CD8 naive T cell counts decrease progressively in HIV-infected adults
28. Regulation of CD27 expression on subsets of mature T-lymphocytes
29. + T cells contain cells with high levels of lymphocyte function-associated antigen-a expression, a phenotype of primed T cells
30. - cells are induced by antigen and evolve through extensive rounds of division
31. Topographic localization of the heparin-binding domain of the neural cell adhesion molecule N-CAM
32. A heparin-binding domain from N-CAM is involved in neural cell-substratum adhesion
33. Functional characterization of chondroitin sulfate proteoglycans of brain: Interactions with neurons and neural cell adhesion molecules
34. Interactions of the chondroitin sulfate proteoglycan phosphacan, the extracellular domain of a receptor-type protein tyrosine phosphatase, with neurons, glia, and neural cell adhesion molecules
35. IL-15, and immunomodulator of T cell responses in intracellular infection