Neurotrophin-3 inhibits HCO3- absorption via a cAMP-dependent pathway in renal thick ascending limb

American Journal of Physiology - Cell Physiology

Volumn 281, Issue 6 50-6, 2001, Pages

  Good, David W ^a   George, Thampi ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Kidney; Nerve growth factor; Neurotrophic factors; Trk receptors; Vasopressin

Indexed keywords

8 BROMO CYCLIC AMP; AMIDE; BICARBONATE; BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; FORSKOLIN; GENISTEIN; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR; NEUROTROPHIN; NEUROTROPHIN 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C; TYROSINE KINASE RECEPTOR; VASOPRESSIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; HENLE LOOP; ION TRANSPORT; KIDNEY TUBULE ABSORPTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0035662131     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.2001.281.6.c1804     Document Type: Article

References (59)

1. GDNF family neurotrophic factor signaling: Four masters, one servant?
2. PD098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
3. Expression of NHE-3 in the apical membrane of rat renal proximal tubule and thick ascending limb
4. Neurotrophic factors in peripheral neuropathies: Therapeutic implications
5. Neurotrophin-5: A novel neurotrophic factor that activates trk and trkB
6. Monoclonal antibodies for high-resolution localization of NHE3 in adult and neonatal rat kidney
7. 2 in rat medullary thick ascending limb cells
8. Functional interactions of neurotrophins and neurotrophin receptors
9. NTR: A receptor after all
10. Gating of BDNF-induced synaptic potentiation by cAMP
11. Prior exposure to neurotrophins blocks inhibition of axonal regeneration by MAG and myelin via a cAMP-dependent mechanism
12. Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: Developmental and topographical expression in the brain
13. Identification of a novel inhibitor of mitogen-activated protein kinase kinase
14. Neurotrophin signaling via Trks and p75
15. Inhibition of bicarbonate absorption by peptide hormones and cyclic adenosine monophosphate in rat medullary thick ascending limb
16. The thick ascending limb as a site of renal bicarbonate reabsorption
17. - absorption in rat medullary thick ascending limb via a protein tyrosine kinasedependent pathway
18. - absorption in rat MTAL by activation of protein kinase C
19. - absorption in thick ascending limb: Modifying effects of vasopressin
20. 2 regulation of ion transport is absent in medullary thick ascending limbs from spontaneously hypertensive rats
21. - absorption in renal thick ascending limb via PI3-kinase
22. - absorption via a cytochrome P450-dependent signaling pathway in rat medullary thick ascending limb
23. Dissecting the mode of action of a neuronal growth factor
24. Pseudosubstrate inhibition of cyclic AMP-dependent protein kinase in intact pancreatic islets: Effects on cyclic AMP-dependent and glucose-dependent insulin secretion
25. The regulated secretion and vectorial targeting of neurotrophins in neuroendocrine and epithelial cells
26. Neurotrophin and neurotrophin receptors in human fetal kidney
27. Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells
28. Nerve growth factor acts through cAMP-dependent protein kinase to increase the number of sodium channels in PC12 cells
29. Signal transduction by the neurotrophin receptors
30. Neurotrophin signal transduction in the nervous system
31. Tissue distribution and immunocytochemical localization of neurotrophin-3 in the brain and peripheral tissues of rats
32. The molecular basis for understanding neurotrophins and their relevance to neurologic disease
33. 3 responses in PC12 cells
34. Physiology of the neurotrophins
35. Widespread neurotrophin receptor expression in the immune system and other nonneural rat tissues
36. Neurotrophin-3: A neurotrophic factor related to NGF and BDNF
37. Urine concentration and dilution
38. Acute regulation of proximal tubule apical membrane Na/H exchanger NHE-3: Role of phosphorylation, protein trafficking, and regulatory factors
39. Renal and neuronal abnormalities in mice lacking GDNF
40. Defects in enteric innervation and kidney development in mice lacking GDNF
41. ras in PC12 cells by distinct, convergent pathways involving tyrosine phosphorylation
42. Binding of brain-derived neurotrophic factor to the nerve growth factor receptor
43. Binding of neurotrophin-3 to its neuronal receptors and interactions with nerve growth factor and brain-derived neurotrophic factor
44. Primary structure and biological activity of a novel human neurotrophic factor
45. Immunocytochemical localization of nerve growth factor in mouse kidney
46. Renal agenesis and the absence of enteric neurons in mice lacking GDNF
47. Development of pharmacological agents for targeting neurotrophins and their receptors
48. Intracellular signaling pathways activated by neurotrophic factors
49. Cellular localization of the Trk neurotrophin receptor family in human non-neural tissues
50. Functions of the neurotrophins during nervous system development: What the knockouts are teaching us
51. The rat trkC locus encodes multiple neurogenic receptors that exhibit differential response to neurotrophin-3 in PC12 cells
52. - absorption via distinct pathways in thick ascending limb
53. - absorption by nerve growth factor in medullary thick ascending limb
54. + exchange
55. - absorption in renal thick ascending limb
56. The cyclic adenosine monophosphate-dependent protein kinase is required for the sustained activation of mitogen-activated kinases and gene expression by nerve growth factor
57. Early BDNF, NT-3, and NT-4 signaling events
58. Neurotrophin regulation of beta-actin mRNA and protein localization within growth cones
59. Localization of neurotrophin-3-like immunoreactivity in peripheral tissues of the rat