Evidence for an association of the R485K polymorphism in the coagulation factor V gene with severe preeclampsia from screening 35 polymorphisms in 27 candidate genes

Thrombosis and Haemostasis

Volumn 86, Issue 6, 2001, Pages 1594-1595

  Watanabe, H ^a   Hamada, H ^a   Yamakawa Kobayashi, K ^a   Yoshikawa, H ^a   Arinami, T ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 5;

CARDIOVASCULAR DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DNA POLYMORPHISM; FEMALE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC CODE; GENETIC SCREENING; GENOTYPE; HERITABILITY; HUMAN; JAPAN; LETTER; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PREECLAMPSIA; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK FACTOR;

EID: 0035652441     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1616777     Document Type: Letter

References (13)

1. New insights into the genetics of preeclampsia
2. ACOG technical bulletin. Hypertension in pregnancy. Number 219
3. Association of the R485K polymorphism of the factor V gene with poor response to activated protein C and increased risk of coronary artery disease in the Chinese population
4. Incidence of activated protein C resistance caused by the ARG 506 GLN mutation in factor V in 113 unrelated symptomatic protein C-deficient patients. The French Network on the behalf of INSERM
5. A polymorphism nt 1628G→A (R485K) in exon 10 of the coagulation factor V gene may be a risk factor for thrombosis in the indigenous Thai population
6. Factor V Leiden, C > T MTHFR polymorphism and genetic susceptibility to preeclampsia
7. Detection of factor V Leiden mutation in severe pre-eclamptic Hungarian women
8. Maternal and neonatal outcome of preeclamptic pregnancies: The potential roles of factor V Leiden mutation and 5,10 methylenetetrahydrofolate reductase
9. World distribution of factor V Leiden
10. Absence of factor V Leiden in the Japanese
11. The factor V Leiden mutation and the prothrombin G20210A mutation was not found in Japanese patients with pulmonary thromboembolism
12. Methylenetetrahydrofolate reductase polymorphism and pre-eclampsia
13. Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy