Absence of factor V Leiden in the Japanese

Thrombosis Research

Volumn 81, Issue 5, 1996, Pages 595-596

  Ozawa, Tetsuo ^a   Niiya, Kenji ^a   Sakuragawa, Nobuo ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Activated protein C resistance; Factor V; Japanese; Mutation

Indexed keywords

BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 5 LEIDEN;

GENETICS; HUMAN; JAPAN; LETTER; POINT MUTATION;

FACTOR V; HUMANS; JAPAN; POINT MUTATION;

EID: 0030090850     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/0049-3848(96)00034-5     Document Type: Letter

References (8)

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2. GRIFFIN, J.H., EVATT, B., WIDEMAN, C., and FERNÁNDEZ, J.A. Anticoagulant protein C pathway defective in majority of thrombophilic patients. Blood 82 , 1989-1993, 1993.
3. KOSTER, T., ROSENDAAL, F.R., DE RONDE, H., BRIËT, E., VANDENBROUCKE, J.P., and BERTINA, R.M. Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study. Lancet 342, 1503-1506, 1994.
4. BERTINA, R.M., KOELEMAN, B.P.C., KOSTER, T., ROSENDAAL, F.R., DIRVEN, R.J., DE RONDE, H., VAN DER VELDEN, P.A. and REITSMA, P.H. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 369, 64-67, 1994.
5. GREENGARD, J.S., SUN, X., XU, X., FERNANDEZ, J.A., GRIFFIN, J.H., EVATT, B. Activated protein C resistance caused by Arg506 Gln mutation in factor Va. Lancet 343, 1361-1362, 1994.
6. ZÖLLER, B., SVENSSON, P.J., HE, X., DAHLBÄCK, B. Identification of the same factor V gene mutation in 47 out of 50 thrombosis-prone families with inherited resistance to activated protein C. J Clin Invest 94, 2521-2524, 1994.
7. KAMBAYASHI, J., FUJIMURA, H., KAWASAKI, T., SAKON, M., MONDEN, M., SUESHIMA, N., and AMINO, N. The incidence of activated protein C resistance among patients with deep vein thrombosis and healthy subjects in Osaka. Thromb Res 79, 227-29, 1995.
8. TAKAMIYA, O., ISHIDA, F., KODAIRA, H., and KITANO, K. APC-Resistancc and Mnl I genotype (Gln 506) of coagulation factor V are rare in Japanese population. Thromb Hemost 74, 996, 1995.