Origin and differentiation of dendritic cells

Trends in Immunology

Volumn 22, Issue 12, 2001, Pages 691-700

  Ardavín, Carlos ^a   Martínez Del Hoyo, Gloria ^a   Martín, Pilar ^a   Anjuère, Fabienne ^b   Arias, Cristina F ^a   Marín, Alvaro R ^a   Ruiz, Sara ^a   Parrillas, Verónica ^a   Hernández, Héctor ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD11 ANTIGEN; CD34 ANTIGEN; CD40 ANTIGEN; CD45 ANTIGEN; INTERLEUKIN DERIVATIVE; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA;

CANCER IMMUNOTHERAPY; CELL DIFFERENTIATION; CELL MATURATION; CELL SUBPOPULATION; DENDRITIC CELL; HUMAN; LYMPHOID CELL; MODEL; NONHUMAN; PROMYELOCYTE; REVIEW; SIGNAL TRANSDUCTION; STEM CELL; T LYMPHOCYTE;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; CELLS, CULTURED; DENDRITIC CELLS; HUMANS; MICE;

EID: 0035652439     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1471-4906(01)02059-2     Document Type: Review

References (67)

1. Dendritic-cell vaccines for cancer immunotherapy
2. Immunobiology of dendritic cells
3. Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation and tissue distribution
4. Murine hematopoietic stem cells committed to macrophage dendritic-cell formation: Stimulation by Flk2 ligand with enhancement by regulators using the gp130 receptor chain
5. Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo
6. Thymic dendritic cells
7. CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus
8. Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population
9. + human thymic precursors can be traced by the differential expression of CD44
10. dim cells in the human thymus can differentiate into T, natural killer and dendritic cells but are distinct from pluripotent stem cells
11. + differentiation pathway
12. Development of dendritic cells in culture from human and murine thymic precursor cells
13. Human T, B, natural killer and dendritic cells arise from a common bone marrow progenitor-cell subset
14. The nature of the principal type-1-interferon-producing cells in human blood
15. Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon
16. The enigmatic plasmacytoid T cells develop into dendritic cells with interleukin (IL)-3 and CD40 ligand
17. Expression of pTα mRNA in a committed dendritic-cell precursor in the human thymus
18. + stem cells into pre-dendritic cell (pre-DC)2 but not into pre-DC1: Evidence for a lymphoid origin of pre-DC2
19. Dendritic-cell ontogeny: A human dendritic-cell lineage of myeloid origin
20. Thymic dendritic-cell precursors: Relationship to the T-lymphocyte lineage and phenotype of the dendritic-cell progeny
21. low lymphoid-committed precursors
22. + dendritic cells from a common myeloid progenitor
23. Dendritic-cell potentials of early lymphoid and myeloid progenitors
24. Transforming growth factor β1 polarizes murine hematopoietic progenitor cells to generate Langerhans-cell-like dendritic cells through a monocyte/macrophage differentiation pathway
25. Langerhans cells develop from a lymphoid-committed precursor
26. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte-macrophage colony-stimulating factor plus interleukin-4 and down-regulated by tumor necrosis factor α
27. + hematopoietic progenitors from human cord blood differentiate along two independent dendritic-cell pathways in response to GM-CSF and TNF-α
28. + bone marrow hematopoietic progenitor cells
29. Bone-marrow-derived dendritic cells pulsed with synthetic peptides elicit protective and therapeutic antitumour immunity
30. Generation and functional characterization of mouse monocytederived dendritic cells
31. Generation of murine dendritic cells from flt3-ligand-supplemented bone-marrow cultures
32. Dendritic-cell development in culture from thymic precursor cells in the absence of granulocyte-macrophage colony-stimulating factor
33. Definition of dendritic-cell subpopulations present in the spleen, Peyer's patches, lymph nodes and skin of the mouse
34. A role for endogenous transforming growth factor β1 in Langerhans-cell biology: The skin of transforming growth factor β1 null mice is devoid of epidermal Langerhans cells
35. + dendritic cells in vivo
36. - dendritic cells regulate T-cell responses
37. + precursor cells develop into Langerhans cells in a TGF-β1-dependent manner
38. Transforming growth factor β1 in the presence of granulocyte-macrophage colony-stimulating factor and interleukin-4, induces differentiation of human peripheral blood monocytes into dendritic Langerhans cells
39. + subset of human blood dendritic cells is a direct precursor of Langerhans cells
40. + hematopoietic stem cells
41. Generation of mature dendritic cells from human blood. An improved method with special regard to clinical applicability
42. Cycling of human dendritic-cell effector phenotypes in response to TNF-α: Modification of the current 'maturation' paradigm and implications for in vivo immunoregulation
43. GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells
44. Human thymus contains two distinct dendritic-cell populations
45. + peripheral-blood dendritic cells are differentially regulated by cytokines
46. The influence of granulocyte-macrophage colony-stimulating factor on dendritic-cell levels in mouse lymphoid organs
47. + murine hematopoietic progenitor cells
48. The requirement of membrane lymphotoxin for the presence of dendritic cells in lymphoid tissues
49. Proliferating dendritic-cell progenitors in human blood
50. Dramatic increase in the numbers of functionally mature dendritic cells in Flt3-ligand-treated mice: Multiple dendritic-cell subpopulations identified
51. Generation of human dendritic-cell subsets by Flt3 ligand
52. - dendritic-cell precursors
53. Mice lacking Flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells and natural killer cells
54. + cells in cancer patients
55. The Ikaros gene is required for the development of all lymphoid lineages
56. Cell-autonomous defects in dendritic-cell populations of Ikaros mutant mice point to a developmental relationship with the lymphoid lineage
57. Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation
58. Cells in the marginal zone of the spleen
59. PU.1 is required for myeloid-derived but not lymphoid-derived dendritic cells
60. + dendritic cells
61. Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB/Rel family
62. Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors
63. Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines
64. - cells with both lymphoid and myeloid potential
65. - cells, as well as macrophages
66. Bipotential B-macrophage progenitors are present in adult bone marrow
67. - dendritic cell subset by a maturation process involving CD8α, DEC-205 and CD24 upregulation