SH2 domain-containing inositol polyphosphate 5′-phosphatase is the main mediator of the inhibitory action of the mast cell function-associated antigen

Journal of Immunology

Volumn 167, Issue 11, 2001, Pages 6394-6402

  Xu, R ^a   Abramson, J ^a   Fridkin, M ^a   Pecht, I ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ANTIGEN; IMMUNOGLOBULIN FC FRAGMENT; INOSITOL PHOSPHATE; INOSITOL POLYPHOSPHATE 5' PHOSPHATASE; LECTIN; MAST CELL FUNCTION ASSOCIATED ANTIGEN; MEMBRANE PROTEIN; PERVANADATE; PHOSPHATASE; PROTEIN KINASE; PROTEIN KINASE LYN; PROTEIN KINASE P60; PROTEIN SH2; PROTEIN SHIP; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE 2; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; ENZYME INHIBITION; ENZYME STRUCTURE; GENE OVEREXPRESSION; IMMUNORECEPTOR TYROSINE BASED INHIBITORY MOTIF; INHIBITION KINETICS; MAST CELL; MEMBRANE STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RAT; STIMULUS RESPONSE;

EID: 0035576222     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.11.6394     Document Type: Article

References (38)

1. A monoclonal antibody that inhibits secretion from rat basophilic leukemia cells and binds to a novel membrane component
2. Analysis of the genes encoding the mast cell function-associated antigen and its alternatively spliced transcripts
3. The mast cell function-associated antigen exhibits saccharide binding capacity
4. A secretion inhibitory signal transduction molecule on mast cells is another C-type lectin
5. MAFA, an ITIM-containing receptor encoded by the human NK cell gene complex and expressed by basophils and NK cells
6. Virus-activated CD8 T cells and lymphokine-activated NK cells express the mast cell function-associated antigen, an inhibitory C-type lectin
7. NK cell expression of killer cell lectin-like receptor G1 (KLRGI), the mouse homolog of MAFA, is modulated by MHC class I molecules
8. An immunoreceptor tyrosine-based inhibitory motif, with serine at site Y-2, binds SH2-domain-containing phosphatases
9. The protein tyrosine kinase Syk activity is reduced by clustering the mast cell function- associated antigen
10. A study of the distribution of 2,4-dinitrobenzene sensitizers between isolated lymph node cells and extra-cellular medium in relation to induction of contact skin sensitivity
11. β heavy chain haplotype
12. 2 suitable for clinical use from mouse IgG1
13. Identification of multiple novel polypeptide substracts of the v-src, v-yes, v-fps, v-ros and v-erbB oncogenic tyrosine protein kinases utilizing antisera against phosphotyrosine
14. Charaterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells
15. Negative signaling pathways of the killer cell inhibitory receptor and FcγRIIb1 require distinct phosphatases
16. Cutting edge: Extracellular signal-regulated kinase activates Syk. A new potential feedback regulation of Fcε receptor signaling
17. Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa
18. The negative signaling molecule SH2 domain-containing inositol-polyphosphate 5-phosphatase (SHIP) binds to the tyrosine-phosphorylated β subunit of the high affinity IgE receptor
19. Proximity relationships between the type I receptor for Fcε (FcεRI) and the mast cell function-associated antigen (MAFA) studied by donor photobleaching fluorescence resonance energy transfer microscopy
20. Characterization of Fcγ receptors on rat mucosal mast cells using a mutant FcεRI-deficient rat basophilic leukemia line
21. Molecular mechanisms in B cell antigen receptor signaling
22. Paired immunoglobulin-like receptor B (PIR-B) inhibits BCR-induced activation of Syk and Btk by SHP-1
23. Signalling through the high-affinity IgE receptor FcεRI
24. Fcε receptor I-associated lyn-dependent phosphorylation of Fcγ receptor IIB during negative regulation of mast cell activation
25. 3 and inhibition of mast cell degranulation
26. The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase
27. p150ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity
28. Structure, function, and biology of SHIP proteins
29. Bilevel control of B-cell activation by the inositol 5-phosphatase SHIP
30. Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FcγRIIB
31. Deletion of SHIP or SHP-1 reveals two distinct pathways for inhibitory signaling
32. The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation
33. Effects of src homology domain 2 (SH2)-containing inositol phosphatase (SHIP), SH2-containing phosphotyrosine phosphatase (SHP)-1, and SHP-2 SH2 decoy proteins on FcγRIIB1-effector interactions and inhibitory functions
34. SHIP modulates immune receptor responses by regulating membrane association of Btk
35. Phosphatidylinbsitol-3,4,5-trisphosphate (Ptdlns-3,4,5-3)/Tec kinase-dependent calcium signaling pathway: A target for SHIP-mediated inhibitory signals
36. BLNK: Connecting Syk and Btk to calcium signals
37. 2+ mobilization by Src homology 2 domain-containing inositol 5′-phosphatase (SHIP)