The carboxyl terminus of the granulocyte colony-stimulating factor receptor, truncated in patients with severe congenital neutropenia/acute myeloid leukemia, is required for SH2-containing phosphatase-1 suppression of Stat activation

Journal of Immunology

Volumn 167, Issue 11, 2001, Pages 6447-6452

  Dong, F ^a   Qiu, Y ^a   Yi, T ^a   Touw, I P ^a   Larner, A C ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATASE; PROTEIN KINASE B; PROTEIN TYROSINE PHOSPHATASE SHP 1; SH2 CONTAINING PHOSPHATASE 1; STAT PROTEIN; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; ARTICLE; BONE MARROW CELL; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CHICKEN; CONGENITAL DISORDER; CONGENITAL NEUTROPENIA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; ENZYME ACTIVATION; ENZYME MECHANISM; GENE MUTATION; MOLECULAR DYNAMICS; NEUTROPENIA; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR DOWN REGULATION; RECEPTOR GENE; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

EID: 0035575765     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.11.6447     Document Type: Article

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