메뉴 건너뛰기




Volumn 102, Issue 1, 1998, Pages 86-93

Local treatment with IL-12 is an effective inhibitor of airway hyperresponsiveness and lung eosinophilia after airway challenge in sensitized mice

Author keywords

Adverse effects; Airway inflammation; Allergen; Body plethysmography; IL 12; Mice; Respiratory hypersensitivity

Indexed keywords

CYTOKINE; INTERLEUKIN 4; INTERLEUKIN 5; RECOMBINANT INTERLEUKIN 12;

EID: 0031817368     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(98)70058-2     Document Type: Article
Times cited : (93)

References (40)
  • 2
    • 0026666718 scopus 로고
    • Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage
    • Walker C, Bode E, Boer L, Hansel TT, Blaser K, Virchow JC Jr. Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage. Am Rev Respir Dis 1992;146:109-15.
    • (1992) Am Rev Respir Dis , vol.146 , pp. 109-115
    • Walker, C.1    Bode, E.2    Boer, L.3    Hansel, T.T.4    Blaser, K.5    Virchow Jr., J.C.6
  • 5
    • 0031110132 scopus 로고    scopus 로고
    • + T cells, eosinophils, and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics
    • + T cells, eosinophils, and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics. J Immunol 1997;158:3539-44.
    • (1997) J Immunol , vol.158 , pp. 3539-3544
    • Ying, S.1    Humbert, M.2    Barkans, J.3    Corrigan, C.J.4    Pfister, R.5    Menz, G.6
  • 7
    • 0028178309 scopus 로고
    • Nebulized but not parenteral IFN-γ decreases IgE production and normalizes airways function in a murine model of allergen sensitization
    • Lack G, Renz H, Saloga J, Bradley KL, Loader J, Leung DYM, et al. Nebulized but not parenteral IFN-γ decreases IgE production and normalizes airways function in a murine model of allergen sensitization. J Immunol 1994;152:2546-54.
    • (1994) J Immunol , vol.152 , pp. 2546-2554
    • Lack, G.1    Renz, H.2    Saloga, J.3    Bradley, K.L.4    Loader, J.5    Leung, D.Y.M.6
  • 8
    • 0030586669 scopus 로고    scopus 로고
    • Nebulized IFN-γ inhibits the development of secondary allergic responses in mice
    • Lack G, Bradley KL, Hamelmann E, Renz H, Loader J, Leung DYM, et al. Nebulized IFN-γ inhibits the development of secondary allergic responses in mice. J Immunol 1996;157:1432-9.
    • (1996) J Immunol , vol.157 , pp. 1432-1439
    • Lack, G.1    Bradley, K.L.2    Hamelmann, E.3    Renz, H.4    Loader, J.5    Leung, D.Y.M.6
  • 9
    • 0024467154 scopus 로고
    • Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes
    • Kobayashi M, Fitz L, Ryan M, Hewick RM, Clark SC, Chan S, et al. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J Exp Med 1989;170:827-46.
    • (1989) J Exp Med , vol.170 , pp. 827-846
    • Kobayashi, M.1    Fitz, L.2    Ryan, M.3    Hewick, R.M.4    Clark, S.C.5    Chan, S.6
  • 10
    • 0025028960 scopus 로고
    • Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells
    • Stern AS, Podlaski FJ, Hulmes JD, Pan YE, Quinn PM, Wolitzky AG, et al. Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells. Proc Natl Acad Sci USA 1990;87:6808-12.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6808-6812
    • Stern, A.S.1    Podlaski, F.J.2    Hulmes, J.D.3    Pan, Y.E.4    Quinn, P.M.5    Wolitzky, A.G.6
  • 11
    • 0026701132 scopus 로고
    • Production of natural killer cell stimulatory factor (NKSF/IL-12) by peripheral blood mononuclear cells
    • D'Andrea A, Rengaraju M, Valiante NM, Chehmini J, Kubin M, Aste-Amezaga M, et al. Production of natural killer cell stimulatory factor (NKSF/IL-12) by peripheral blood mononuclear cells. J Exp Med 1992;176:1387-98.
    • (1992) J Exp Med , vol.176 , pp. 1387-1398
    • D'Andrea, A.1    Rengaraju, M.2    Valiante, N.M.3    Chehmini, J.4    Kubin, M.5    Aste-Amezaga, M.6
  • 12
    • 0025819340 scopus 로고
    • Induction of IFN-γ production by NK cell stimulatory factor (NKSF): Characterization of the responder cells and synergy with other inducers
    • Chan S, Perussia B, Gupta JW, Kobayashi M, Pospisil M, Young HA, et al. Induction of IFN-γ production by NK cell stimulatory factor (NKSF): characterization of the responder cells and synergy with other inducers. J Exp Med 1991;173:869-79.
    • (1991) J Exp Med , vol.173 , pp. 869-879
    • Chan, S.1    Perussia, B.2    Gupta, J.W.3    Kobayashi, M.4    Pospisil, M.5    Young, H.A.6
  • 14
    • 0027409793 scopus 로고
    • Natural killer cell stimulatory factor (NKSF/IL-12) induces Th-1 type specific immune responses and inhibits the development of IL-4 producing Th cells
    • Manetti R, Parronchi P, Giudizi MG, Picinni M-P, Maggi E, Trinchieri G, et al. Natural killer cell stimulatory factor (NKSF/IL-12) induces Th-1 type specific immune responses and inhibits the development of IL-4 producing Th cells. J Exp Med 1993;177:1199-204.
    • (1993) J Exp Med , vol.177 , pp. 1199-1204
    • Manetti, R.1    Parronchi, P.2    Giudizi, M.G.3    Picinni, M.-P.4    Maggi, E.5    Trinchieri, G.6
  • 17
    • 0030293642 scopus 로고    scopus 로고
    • Immunomodularory effect of IL-12 on allergic lung inflammation depend on timing of doses
    • Sur S, Lam J, Bouchard P, Sigounas A, Holbert D, Metzger WJ. Immunomodularory effect of IL-12 on allergic lung inflammation depend on timing of doses. J Immunol 1996;157:4173-80.
    • (1996) J Immunol , vol.157 , pp. 4173-4180
    • Sur, S.1    Lam, J.2    Bouchard, P.3    Sigounas, A.4    Holbert, D.5    Metzger, W.J.6
  • 19
    • 0029847440 scopus 로고    scopus 로고
    • Interleukin-12 prevents antigen-induced eosinophil recruitment into mouse airways
    • Iwamoto I, Kumano K, Masai M, Kurasawa K, Nakao A. Interleukin-12 prevents antigen-induced eosinophil recruitment into mouse airways. Am J Respir Crit Care Med 1996;154:1257-60.
    • (1996) Am J Respir Crit Care Med , vol.154 , pp. 1257-1260
    • Iwamoto, I.1    Kumano, K.2    Masai, M.3    Kurasawa, K.4    Nakao, A.5
  • 21
    • 0028096083 scopus 로고
    • Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFN-γ in vivo
    • Gately MK, Warrier RR, Honasoge S, Carvajal DM, Faherty DA, Connaughton SE, et al. Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFN-γ in vivo. Int Immunol 1994;6:157-67.
    • (1994) Int Immunol , vol.6 , pp. 157-167
    • Gately, M.K.1    Warrier, R.R.2    Honasoge, S.3    Carvajal, D.M.4    Faherty, D.A.5    Connaughton, S.E.6
  • 22
    • 0028916621 scopus 로고
    • The stimulatory effects of interleukin (IL)-12 in hematopoiesis are antagonized by IL-12-induced interferon-γ in vivo
    • Eng VM, Car BD, Schnyder B, Lorenz M, Lugli S, Aguet M, et al. The stimulatory effects of interleukin (IL)-12 in hematopoiesis are antagonized by IL-12-induced interferon-γ in vivo. J Exp Med 1995;181:1893-8.
    • (1995) J Exp Med , vol.181 , pp. 1893-1898
    • Eng, V.M.1    Car, B.D.2    Schnyder, B.3    Lorenz, M.4    Lugli, S.5    Aguet, M.6
  • 24
    • 0029047009 scopus 로고
    • Biology of disease, IL-12, biological activity, therapeutic utility, and role in disease
    • Hendrzak JA, Brunda MJ. Biology of disease, IL-12, biological activity, therapeutic utility, and role in disease. Lab Invest 1995;72:619-37.
    • (1995) Lab Invest , vol.72 , pp. 619-637
    • Hendrzak, J.A.1    Brunda, M.J.2
  • 25
    • 0028290845 scopus 로고
    • Dual stimulatory and inhibitory effect of NK cell stimulatory factor/IL-12 on human hematopoiesis
    • Bellone G, Trinchieri G. Dual stimulatory and inhibitory effect of NK cell stimulatory factor/IL-12 on human hematopoiesis. J Immunol 1994;153:930-7.
    • (1994) J Immunol , vol.153 , pp. 930-937
    • Bellone, G.1    Trinchieri, G.2
  • 26
    • 0029062597 scopus 로고
    • IL-12 at the crossroads
    • Hall SS. IL-12 at the crossroads [news]. Science 1995;268:1432-4.
    • (1995) Science , vol.268 , pp. 1432-1434
    • Hall, S.S.1
  • 28
    • 0027584575 scopus 로고
    • Isolation and partial characterization of subpopulations of alveolar macrophages, granulocytes and highly enriched interstitial macrophages from rat lung
    • Lavnikova N, Prokhorova S, Heylar L, Laskin DL. Isolation and partial characterization of subpopulations of alveolar macrophages, granulocytes and highly enriched interstitial macrophages from rat lung. Am J Respir Cell Mol Biol 1993;8:384-92.
    • (1993) Am J Respir Cell Mol Biol , vol.8 , pp. 384-392
    • Lavnikova, N.1    Prokhorova, S.2    Heylar, L.3    Laskin, D.L.4
  • 29
    • 0029960804 scopus 로고    scopus 로고
    • Passive transfer of immediate hypersensitivity and airway hyperresponsiveness by allergen-specific immunoglobulin (Ig) E and IgG1 in mice
    • Oshiba A, Hamelmann E, Takeda K, Bradley K, Loader JE, Larsen GL, et al. Passive transfer of immediate hypersensitivity and airway hyperresponsiveness by allergen-specific immunoglobulin (Ig) E and IgG1 in mice. J Clin Invest 1996;97:1398-408.
    • (1996) J Clin Invest , vol.97 , pp. 1398-1408
    • Oshiba, A.1    Hamelmann, E.2    Takeda, K.3    Bradley, K.4    Loader, J.E.5    Larsen, G.L.6
  • 30
    • 0030969430 scopus 로고    scopus 로고
    • Anti-interleukin 5 (IL-5) antibody prevents airway hyperresponsiveness in a murine model of airway sensitization
    • Hamelmann E, Oshiba A, Loader J, Larsen GL, Gleich G, Lee J, et al. Anti-interleukin 5 (IL-5) antibody prevents airway hyperresponsiveness in a murine model of airway sensitization. Am J Respir Crit Care Med 1997;155:819-25.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 819-825
    • Hamelmann, E.1    Oshiba, A.2    Loader, J.3    Larsen, G.L.4    Gleich, G.5    Lee, J.6
  • 31
    • 0023693868 scopus 로고
    • The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent assay
    • Schumacher JH, O'Garra A, Shrader B, van Kimmenade A, Bond MW, Mosmann TR, et al. The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent assay. J Immunol 1988;141:1576-81.
    • (1988) J Immunol , vol.141 , pp. 1576-1581
    • Schumacher, J.H.1    O'Garra, A.2    Shrader, B.3    Van Kimmenade, A.4    Bond, M.W.5    Mosmann, T.R.6
  • 32
    • 0030028768 scopus 로고    scopus 로고
    • Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model
    • Foster PS, Hogan SP, Ramsay AJ, Matthaei KI, Young IG. Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J Exp Med 1996;183:195-201.
    • (1996) J Exp Med , vol.183 , pp. 195-201
    • Foster, P.S.1    Hogan, S.P.2    Ramsay, A.J.3    Matthaei, K.I.4    Young, I.G.5
  • 33
    • 0028821825 scopus 로고
    • Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice
    • Gavett SH, O'Hearn DJ, Li X, Huang SK, Finkelmann FD, Wills-Karp M. Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice. J Exp Med 1995;182:1527-36.
    • (1995) J Exp Med , vol.182 , pp. 1527-1536
    • Gavett, S.H.1    O'Hearn, D.J.2    Li, X.3    Huang, S.K.4    Finkelmann, F.D.5    Wills-Karp, M.6
  • 35
    • 0025216937 scopus 로고
    • Lymphokine control of in vivo immunoglobulin isotype selection
    • Finkelman FD, Holmes J. Lymphokine control of in vivo immunoglobulin isotype selection. Annu Rev Immunol 1990;8:303-33.
    • (1990) Annu Rev Immunol , vol.8 , pp. 303-333
    • Finkelman, F.D.1    Holmes, J.2
  • 36
    • 0030068235 scopus 로고    scopus 로고
    • Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity
    • Corry DB, Folkesson HG, Warnock ML, Erle DJ, Matthay MA, Wiener-Kronish JP, et al. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J Exp Med 1996;183:109-17.
    • (1996) J Exp Med , vol.183 , pp. 109-117
    • Corry, D.B.1    Folkesson, H.G.2    Warnock, M.L.3    Erle, D.J.4    Matthay, M.A.5    Wiener-Kronish, J.P.6
  • 37
    • 0028966757 scopus 로고
    • T cells are necessary for Th2 cytokine production and eosinophil accumulation in airways of antigen-challenged allergic mice
    • Garlisi CG, Falcone A, Kung TT, Stelts D, Pennline KJ, Beavis AJ, et al. T cells are necessary for Th2 cytokine production and eosinophil accumulation in airways of antigen-challenged allergic mice. Clin Immunol Immunopathol 1995;75:75-83.
    • (1995) Clin Immunol Immunopathol , vol.75 , pp. 75-83
    • Garlisi, C.G.1    Falcone, A.2    Kung, T.T.3    Stelts, D.4    Pennline, K.J.5    Beavis, A.J.6
  • 39
    • 0030445948 scopus 로고    scopus 로고
    • A functional interleukin-12 receptor complex is composed of two beta-type cytokine receptor subunits
    • Presky DH, Yang H, Minetti LJ, Chua AO, Nabavi N, Wu CY, et al. A functional interleukin-12 receptor complex is composed of two beta-type cytokine receptor subunits. Proc Natl Acad Sci USA 1996;93:14002-7.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 14002-14007
    • Presky, D.H.1    Yang, H.2    Minetti, L.J.3    Chua, A.O.4    Nabavi, N.5    Wu, C.Y.6
  • 40
    • 8044250881 scopus 로고    scopus 로고
    • Regulation of the interleukin (IL)-12R β2 subunit expression in developing T helper 1 (Th1) and Th2 cells
    • Szabo SJ, Dighe AS, Gubler U, Murphy KM. Regulation of the interleukin (IL)-12R β2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J Exp Med 1997;185:817-24.
    • (1997) J Exp Med , vol.185 , pp. 817-824
    • Szabo, S.J.1    Dighe, A.S.2    Gubler, U.3    Murphy, K.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.