Inhibition of depolarization-induced [3H]noradrenaline release from SH-SY5Y human neuroblastoma cells by some second-generation H1 receptor antagonists through blockade of store-operated Ca2+ channels (SOCs)

Biochemical Pharmacology

Volumn 62, Issue 9, 2001, Pages 1229-1238

  Taglialatela, Maurizio ^a   Secondo, Agnese ^a   Fresi, Angela ^a   Rosati, Barbara ^b   Pannaccione, Anna ^a   Castaldo, Pasqualina ^a   Giorgio, Giovanna ^a   Wanke, Enzo ^b   Annunziato, Lucio ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF MILANO BICOCCA   (Italy)

Author keywords

Ca2+ channels activated by Cai2+ store depletion; Depolarization induced norepinephrine release; hERG K+ channels; Long QT syndrome; Second generation antihistamines; SH SY5Y human neuroblastoma cells

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); ASTEMIZOLE; CALCIUM CHANNEL; CALCIUM ION; CETIRIZINE; HISTAMINE H1 RECEPTOR; HISTAMINE H1 RECEPTOR ANTAGONIST; HYDROXYZINE; LORATADINE; NIMODIPINE; NORADRENALIN; OMEGA CONOTOXIN; POTASSIUM CHANNEL; POTASSIUM ION; RETINOIC ACID; SARCOPLASMIC ENDOPLASMIC RETICULUM CALCIUM ADENOSINE TRIPHOSPHATASE; TERFENADINE; TETRODOTOXIN; THAPSIGARGIN; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM CELL LEVEL; CELL DIFFERENTIATION; CELL MEMBRANE POTENTIAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPOLARIZATION; DOSE RESPONSE; DRUG EFFECT; DRUG POTENCY; EXTRACELLULAR CALCIUM; GENE; HUMAN; HUMAN CELL; IC 50; NEUROBLASTOMA; NEUROBLASTOMA CELL; NORADRENALIN RELEASE; POTASSIUM CELL LEVEL; PRIORITY JOURNAL; REPOLARIZATION; VOLTAGE CLAMP;

ASTEMIZOLE; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CATION TRANSPORT PROTEINS; CETIRIZINE; DNA-BINDING PROTEINS; ETHER-A-GO-GO POTASSIUM CHANNELS; HISTAMINE H1 ANTAGONISTS; HUMANS; HYDROXYZINE; LORATADINE; NEUROBLASTOMA; NOREPINEPHRINE; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; RECEPTORS, HISTAMINE H1; TERFENADINE; TRANS-ACTIVATORS; TRITIUM; TUMOR CELLS, CULTURED;

EID: 0035504916     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00754-7     Document Type: Article

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