Pharmacological blockade of ERG K+ channels and Ca2+ influx through store-operated channels exerts opposite effects on intracellular Ca2+ oscillations in pituitary GH3 cells

Molecular Pharmacology

Volumn 58, Issue 5, 2000, Pages 1115-1128

  Secondo, Agnese ^a   Taglialatela, Maurizio ^a   Cataldi, Mauro ^a   Giorgio, Giovanna ^a   Valore, Monica ^a   Di Renzo, Gianfranco ^b   Annunziato, Lucio ^a,c  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIARRHYTHMIC AGENT; ANTIHISTAMINIC AGENT; ASTEMIZOLE; CALCIUM CHANNEL BLOCKING AGENT; CETIRIZINE; DOFETILIDE; FURA 2; GENE PRODUCT; HYDROXYZINE; MESYLIC ACID DERIVATIVE; NIMODIPINE; PIPERAZINE DERIVATIVE; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; TERFENADINE; THAPSIGARGIN;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENDOPLASMIC RETICULUM; EXTRACELLULAR CALCIUM; HYPOPHYSIS CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SARCOPLASMIC RETICULUM;

EID: 0033790261     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.58.5.1115     Document Type: Article

References (41)

1. 3 rat anterior pituitary cells
2. 3 rat anterior pituitary cells
3. + current and its modulation by thyrotrophin-releasing hormone in giant clonal rat anterior pituitary cells
4. + current in clonal rat pituitary cells and its modulation by thyrotrophin-releasing hormone
5. + current in prolactin secretion from rat lactotrophs
6. + channels sensitive to antidiabetic sulfonylureas are present in adenohypophysis and are involved in growth hormone release
7. The AM and FM of calcium signalling
8. + current highly conserved in tumors of different histogenesis: A selective advantage for cancer cells?
9. 3 cells
10. Protein tyrosine kinases activate while protein tyrosine phosphatases inhibit L-type calcium channel activity in pituitary cells
11. 3 cells
12. An inactivating inward-rectifying K current present in prolactin cells from the pituitary of lactating rats
13. Calcium oscillations increase the efficiency and specificity of gene expression
14. 2+ stores in LAN-1 human neuroblastoma cells
15. 2+ influx
16. Effects of the anti-allergics astemizole and norastemizole on Fc epsilon RI receptor-mediated signal transduction processes
17. 2+ channels and exocytosis
18. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membranae patches
19. 3 cells
20. Molecular physiology and pharmacology of HERG: Single channel currents and block by dofetilide
21. Endogenous pacemaker activity of rat tumour somatotrophs
22. 2+ channel current in rat ventricular myocytes by terfenadine
23. Calcium spiking
24. + channels in guinea pig ventricular myocytes
25. The high-affinity sulfonylurea receptor: Distribution, glycosylation, purification, and immunoprecipitation of two forms from endocrine and neuroendocrine cell lines
26. Inhibition of L-type calcium-channel activity by thapsigargin and 2,5-t-butyldroquinone, but not by cyclopiazonic acid
27. Store depletion and calcium influx
28. HERG, a primary human ventricular target of the non sedating antihistamine terfenadine
29. 2+ in pituitary cells due to action potentials
30. High affinity open channel block by dofetilide of HERG expressed in a human cell line
31. Special section on calcium signaling in pituitary cells
32. Calcium oscillations in anterior pituitary cells
33. Blockade of HERG channels expressed in Xenopus oocytes by the histamine receptor antagonists terfenadine and astemizole
34. 1 receptor blocker cetirizine as compared to other second-generation antihistamines
35. Cardiotoxic potential and CNS effects of first-generation antihistamines
36. Why are non-sedating antihistamines non-sedating?
37. Dynamic changes in spontaneous intracellular free calcium oscillations and their relationship to prolactin gene expression in single, primary mammotropes
38. A family of potassium channel genes related to eag in Drosophila and mammals
39. Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature
40. Block of HERG potassium channels by the antihistamine astemizole and its metabolites desmethylastemizole and norastemizole