Dual effect of the anti-allergic astemizole on Ca2+ fluxes in rat basophilic leukemia (RBL-2H3) cells: Release of Ca2+ from intracellular stores and inhibition of Ca2+ release-activated Ca2+ influx

Biochemical Pharmacology

Volumn 55, Issue 8, 1998, Pages 1255-1262

  Fischer, Marcel J E ^a   Paulussen, Jeannette J C ^a   De Mol, Nico J ^a   Janssen, Lambert H M ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Astemizole; Ca2+ flux; Exocytosis; RBL 2H3; SOC

Indexed keywords

ASTEMIZOLE; BARIUM; CALCIUM ION; EGTAZIC ACID; FC RECEPTOR; NICKEL; NORASTEMIZOLE; THAPSIGARGIN;

ALLERGENICITY; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL STIMULATION; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; ENDOPLASMIC RETICULUM; EXOCYTOSIS; MAST CELL LEUKEMIA; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY;

ANIMALS; ANTI-ALLERGIC AGENTS; ASTEMIZOLE; BARIUM; CALCIUM; CALCIUM CHANNELS; EXOCYTOSIS; LEUKEMIA, BASOPHILIC, ACUTE; NICKEL; RATS; RECEPTORS, IGE; THAPSIGARGIN; TUMOR CELLS, CULTURED;

EID: 0032522899     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00600-X     Document Type: Article

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