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Volumn 55, Issue 9, 2001, Pages 1679-1687

Synthesis of 5-substituted pyrido[2,3-d]pyrimidines as analogues of the antifolates methotrexate, DDATHF and pemetrexed (LY231514)

(2) Schönfeld, Franz a Troschütz, Reinhard a

a UNIVERSITY OF ERLANGEN NUREMBERG (Germany)

Author keywords

Cyclization; Diethyl L Glutamate; Knoevenagel Reaction

Indexed keywords

ACETAL DERIVATIVE; FOLIC ACID ANTAGONIST; GUANIDINE; HYDROCHLORIC ACID; LOMETREXOL; MALONONITRILE; METHOTREXATE; N [4 [2 (2 AMINO 3,4 DIHYDRO 4 OXOPYRIDO[2,3 D]PYRIMIDIN 5 YL)ETHYL]BENZOYL]GLUTAMIC ACID; N [4 [2 (2 AMINO 3,4,5,6,7,8 HEXAHYDRO 4 OXOPYRIDO[2,3 D]PYRIMIDIN 5 YL)ETHYL]BENZOYL]GLUTAMIC ACID; N [4 [2 (2,4 DIAMINOPYRIDO[2,3D]PYRIMIDIN 5 YL)ETHYL]BENZOYL]GLUTAMIC ACID; N,N DIMETHYLFORMAMIDE; PEMETREXED; PYRIDO[2,3 D]PYRIMIDINE DERIVATIVE; PYRIMIDINE; UNCLASSIFIED DRUG;

ARTICLE; CANCER INHIBITION; CONCENTRATION RESPONSE; CYCLIZATION; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; POLYMERIZATION; REACTION ANALYSIS;

EID: 0035439001 PISSN: 03855414 EISSN: None Source Type: Journal
DOI: 10.3987/com-01-9251 Document Type: Article

Times cited : (15)

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