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Volumn 1, Issue 2, 2001, Pages 95-103

Oral fluoropyrimidine treatment of colorectal cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CAPECITABINE; DEOXYCYTIDINE; DRUG DERIVATIVE; EMITEFUR; FLUOROURACIL; OXALIPLATIN; OXONIC ACID; PLATINUM COMPLEX; PRODRUG; PYRIDINE DERIVATIVE; S 1 (COMBINATION); TEGAFUR;

EID: 0035428097     PISSN: 15330028     EISSN: None     Source Type: Journal    
DOI: 10.3816/CCC.2001.n.009     Document Type: Review
Times cited : (18)

References (51)
  • 1
    • 0001543942 scopus 로고
    • Fluorinated pyrimidines. a new class of tumor inhibiting compounds
    • C Heidelberger N Chaudhuari P Daneberg Fluorinated pyrimidines. a new class of tumor inhibiting compounds Nature 179 1957 633 666
    • (1957) Nature , vol.179 , pp. 633-666
    • Heidelberger, C1    Chaudhuari, N2    Daneberg, P3
  • 2
    • 0344109583 scopus 로고    scopus 로고
    • Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer
    • Meta-analysis Group In Cancer Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer J Clin Oncol 16 1998 301 308
    • (1998) J Clin Oncol , vol.16 , pp. 301-308
    • Meta-analysis Group In Cancer1
  • 3
    • 0024539308 scopus 로고
    • A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: a Mid-Atlantic Oncology Program Study
    • JJ Lokich JD Ahlgren JJ Gullo A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: a Mid-Atlantic Oncology Program Study J Clin Oncol 7 1989 425 432
    • (1989) J Clin Oncol , vol.7 , pp. 425-432
    • Lokich, JJ1    Ahlgren, JD2    Gullo, JJ3
  • 4
    • 0032862554 scopus 로고    scopus 로고
    • 5-fluorouracil pharmacokinetics: causes for variability and strategies for modulation in cancer chemotherapy
    • L Iyer MJ Ratain 5-fluorouracil pharmacokinetics: causes for variability and strategies for modulation in cancer chemotherapy Cancer Invest 17 1999 494 506
    • (1999) Cancer Invest , vol.17 , pp. 494-506
    • Iyer, L1    Ratain, MJ2
  • 5
    • 0024595925 scopus 로고
    • Clinical pharmacology of 5-fluorouracil
    • RB Diasio BE Harris Clinical pharmacology of 5-fluorouracil Clin Pharmacokinet 16 1989 215 237
    • (1989) Clin Pharmacokinet , vol.16 , pp. 215-237
    • Diasio, RB1    Harris, BE2
  • 6
    • 0023187085 scopus 로고
    • Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile
    • GD Heggie JP Sommadossi DS Cross Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile Cancer Res 47 1987 2203 2206
    • (1987) Cancer Res , vol.47 , pp. 2203-2206
    • Heggie, GD1    Sommadossi, JP2    Cross, DS3
  • 7
    • 0031010583 scopus 로고    scopus 로고
    • Inter- and intraindividual variation in dihydropyrimidine dehydrogenase activity in peripheral blood mononuclear cells
    • JL Grem LK Yee DJ Venzon Inter- and intraindividual variation in dihydropyrimidine dehydrogenase activity in peripheral blood mononuclear cells Cancer Chemother Pharmacol 40 1997 117 125
    • (1997) Cancer Chemother Pharmacol , vol.40 , pp. 117-125
    • Grem, JL1    Yee, LK2    Venzon, DJ3
  • 8
    • 0028805308 scopus 로고
    • Population characteristics of hepatic dihydropyrimidine dehydrogenase activity, a key metabolic enzyme in 5-fluorouracil chemotherapy
    • Z Lu R Zhang RB Diasio Population characteristics of hepatic dihydropyrimidine dehydrogenase activity, a key metabolic enzyme in 5-fluorouracil chemotherapy Clin Pharmacol Ther 58 1995 512 522
    • (1995) Clin Pharmacol Ther , vol.58 , pp. 512-522
    • Lu, Z1    Zhang, R2    Diasio, RB3
  • 9
    • 0022400840 scopus 로고
    • Enzymes of uracil catabolism in normal and neoplastic human tissues
    • FN Naguib MH el Kouni S Cha Enzymes of uracil catabolism in normal and neoplastic human tissues Cancer Res 45 1985 5405 5412
    • (1985) Cancer Res , vol.45 , pp. 5405-5412
    • Naguib, FN1    el Kouni, MH2    Cha, S3
  • 10
    • 0002548405 scopus 로고    scopus 로고
    • 5-fluoropyrimidines
    • JL Grem 5-fluoropyrimidines BA Chabner DL Longo Cancer Chemotherapy and Biotherapy 1996 Lippincott-Raven Philadelphia, PA 146 211
    • (1996) , pp. 146-211
    • Grem, JL1
  • 11
    • 0023916753 scopus 로고
    • Circadian-based infusional chrono-chemotherapy controls progressive metastatic renal cell carcinoma
    • WJ Hrushesky R Von Roemeling EE Fraley Circadian-based infusional chrono-chemotherapy controls progressive metastatic renal cell carcinoma Semin Surg Oncol 4 1988 110 115
    • (1988) Semin Surg Oncol , vol.4 , pp. 110-115
    • Hrushesky, WJ1    Von Roemeling, R2    Fraley, EE3
  • 12
    • 0027945196 scopus 로고
    • Dihydropyrimidine dehydrogenase activity and fluorouracil chemotherapy
    • RB Diasio Z Lu Dihydropyrimidine dehydrogenase activity and fluorouracil chemotherapy J Clin Oncol 12 1994 2239 2242
    • (1994) J Clin Oncol , vol.12 , pp. 2239-2242
    • Diasio, RB1    Lu, Z2
  • 13
    • 0031017851 scopus 로고    scopus 로고
    • Patient preferences for oral versus intravenous palliative chemotherapy
    • G Liu E Franssen MI Fitch Patient preferences for oral versus intravenous palliative chemotherapy J Clin Oncol 15 1997 110 115
    • (1997) J Clin Oncol , vol.15 , pp. 110-115
    • Liu, G1    Franssen, E2    Fitch, MI3
  • 14
    • 0019378585 scopus 로고
    • Dose-response effect of adjuvant chemotherapy in breast cancer
    • G Bonadonna P Valagussa Dose-response effect of adjuvant chemotherapy in breast cancer N Engl J Med 304 1981 10 15
    • (1981) N Engl J Med , vol.304 , pp. 10-15
    • Bonadonna, G1    Valagussa, P2
  • 15
    • 0025138455 scopus 로고
    • Patient noncompliance with self-administered chemotherapy
    • AH Lebovits JJ Strain SJ Schleifer Patient noncompliance with self-administered chemotherapy Cancer 65 1990 17 22
    • (1990) Cancer , vol.65 , pp. 17-22
    • Lebovits, AH1    Strain, JJ2    Schleifer, SJ3
  • 16
    • 0031859489 scopus 로고    scopus 로고
    • Oral chemotherapy: rationale and future directions
    • MD DeMario MJ Ratain Oral chemotherapy: rationale and future directions J Clin Oncol 16 1998 2557 2567
    • (1998) J Clin Oncol , vol.16 , pp. 2557-2567
    • DeMario, MD1    Ratain, MJ2
  • 17
    • 0023580351 scopus 로고
    • Compliance with oral drug therapy in patients with hematologic malignancy
    • AM Levine JL Richardson G Marks Compliance with oral drug therapy in patients with hematologic malignancy J Clin Oncol 5 1987 1469 1476
    • (1987) J Clin Oncol , vol.5 , pp. 1469-1476
    • Levine, AM1    Richardson, JL2    Marks, G3
  • 18
    • 0034049660 scopus 로고    scopus 로고
    • Oral chemotherapeutic agents for colorectal cancer
    • S Sharma LB Saltz Oral chemotherapeutic agents for colorectal cancer Oncologist 5 2000 99 107
    • (2000) Oncologist , vol.5 , pp. 99-107
    • Sharma, S1    Saltz, LB2
  • 19
    • 85120210216 scopus 로고    scopus 로고
    • 1999 Drug Topics Red Book 1999 Medical Economics Company Montevale, NJ
    • (1999)
  • 20
    • 0030731885 scopus 로고    scopus 로고
    • A pharmacoeconomic comparison of UFT and 5-FU chemotherapy for colorectal cancer in South America
    • A Murad CA de Andrade C Delfino A pharmacoeconomic comparison of UFT and 5-FU chemotherapy for colorectal cancer in South America Oncology (Huntingt) 11 1997 128 135
    • (1997) Oncology (Huntingt) , vol.11 , pp. 128-135
    • Murad, A1    de Andrade, CA2    Delfino, C3
  • 21
    • 0029790295 scopus 로고    scopus 로고
    • Clinicopathologic and prognostic significance of an angiogenic factor, thymidine phosphorylase, in human colorectal carcinoma
    • Y Takebayashi S Akiyama S Akiba Clinicopathologic and prognostic significance of an angiogenic factor, thymidine phosphorylase, in human colorectal carcinoma J Natl Cancer Inst 88 1996 1110 1117
    • (1996) J Natl Cancer Inst , vol.88 , pp. 1110-1117
    • Takebayashi, Y1    Akiyama, S2    Akiba, S3
  • 22
    • 0032520168 scopus 로고    scopus 로고
    • Positive correlation between the efficacy of capecitabine and doxifluridine and the ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts
    • T Ishikawa F Sekiguchi Y Fukase Positive correlation between the efficacy of capecitabine and doxifluridine and the ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts Cancer Res 58 1998 685 690
    • (1998) Cancer Res , vol.58 , pp. 685-690
    • Ishikawa, T1    Sekiguchi, F2    Fukase, Y3
  • 23
    • 0034016415 scopus 로고    scopus 로고
    • Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients
    • J Schuller J Cassidy E Dumont Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients Cancer Chemother Pharmacol 45 2000 291 297
    • (2000) Cancer Chemother Pharmacol , vol.45 , pp. 291-297
    • Schuller, J1    Cassidy, J2    Dumont, E3
  • 24
    • 0032874395 scopus 로고    scopus 로고
    • The oral fluoropyrimidines in cancer chemotherapy
    • EB Lamont RL Schilsky The oral fluoropyrimidines in cancer chemotherapy Clin Cancer Res 5 1999 2289 2296
    • (1999) Clin Cancer Res , vol.5 , pp. 2289-2296
    • Lamont, EB1    Schilsky, RL2
  • 25
    • 0031859855 scopus 로고    scopus 로고
    • Preliminary studies of a novel oral fluoropyrimidine carbamate: capecitabine
    • DR Budman NJ Meropol B Reigner Preliminary studies of a novel oral fluoropyrimidine carbamate: capecitabine J Clin Oncol 16 1998 1795 1802
    • (1998) J Clin Oncol , vol.16 , pp. 1795-1802
    • Budman, DR1    Meropol, NJ2    Reigner, B3
  • 26
    • 0031671094 scopus 로고    scopus 로고
    • Phase I and pharmacologic study of intermittent twice-daily oral therapy with capecitabine in patients with advanced and/or metastatic cancer
    • M Mackean A Planting C Twelves Phase I and pharmacologic study of intermittent twice-daily oral therapy with capecitabine in patients with advanced and/or metastatic cancer J Clin Oncol 16 1998 2977 2985
    • (1998) J Clin Oncol , vol.16 , pp. 2977-2985
    • Mackean, M1    Planting, A2    Twelves, C3
  • 27
    • 0034016343 scopus 로고    scopus 로고
    • Capecitabine, an oral fluoropyrimidine carbamate with substantial activity in advanced colorectal cancer: results of a randomized phase II study
    • E van Cutsem M Findlay B Osterwalder Capecitabine, an oral fluoropyrimidine carbamate with substantial activity in advanced colorectal cancer: results of a randomized phase II study J Clin Oncol 18 2000 1337 1345
    • (2000) J Clin Oncol , vol.18 , pp. 1337-1345
    • van Cutsem, E1    Findlay, M2    Osterwalder, B3
  • 28
    • 0001021401 scopus 로고    scopus 로고
    • A phase II study of Xeloda (capecitabine) in patients with metastatic colorectal cancer demonstrating progression on 5-FU therapy
    • P Hoff J Abbruzzese D Medgyesy A phase II study of Xeloda (capecitabine) in patients with metastatic colorectal cancer demonstrating progression on 5-FU therapy Proc Am Soc Clin Oncol 19 2000 256a (Abstract #993).
    • (2000) Proc Am Soc Clin Oncol , vol.19 , pp. 256a
    • Hoff, P1    Abbruzzese, J2    Medgyesy, D3
  • 29
    • 0000114292 scopus 로고    scopus 로고
    • A phase III trial (S014796) of Xeloda™ (capecitabine) in previously untreated advanced/metastatic colorectal cancer
    • C Twelves P Harper E van Cutsem A phase III trial (S014796) of Xeloda™ (capecitabine) in previously untreated advanced/metastatic colorectal cancer Proc Am Soc Clin Oncol 18 1999 263a (Abstract #1010).
    • (1999) Proc Am Soc Clin Oncol , vol.18 , pp. 263a
    • Twelves, C1    Harper, P2    van Cutsem, E3
  • 30
    • 0035871538 scopus 로고    scopus 로고
    • Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: results of a randomized phase III study
    • PM Hoff R Ansari G Batist Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: results of a randomized phase III study J Clin Oncol 19 2001 2282 2292
    • (2001) J Clin Oncol , vol.19 , pp. 2282-2292
    • Hoff, PM1    Ansari, R2    Batist, G3
  • 31
    • 0019477355 scopus 로고
    • The pharmacology of ftorafur (R, S-1-(tetrahydro- 2-furanyl)-5-fluorouracil
    • JL Au W Sadee The pharmacology of ftorafur (R, S-1-(tetrahydro- 2-furanyl)-5-fluorouracil Recent Results Cancer Res 76 1981 100 114
    • (1981) Recent Results Cancer Res , vol.76 , pp. 100-114
    • Au, JL1    Sadee, W2
  • 32
    • 0032771857 scopus 로고    scopus 로고
    • Fluoropyrimidines: a critical evaluation
    • RA Brito D Medgyesy TH Zukowski Fluoropyrimidines: a critical evaluation Oncology 57 suppl 1 1999 2 8
    • (1999) Oncology , vol.57 , Issue.suppl 1 , pp. 2-8
    • Brito, RA1    Medgyesy, D2    Zukowski, TH3
  • 33
    • 0030777707 scopus 로고    scopus 로고
    • Experience with UFT in Japan
    • T Taguchi Experience with UFT in Japan Oncology (Huntingt) 11 1997 30 34
    • (1997) Oncology (Huntingt) , vol.11 , pp. 30-34
    • Taguchi, T1
  • 34
    • 0029966745 scopus 로고    scopus 로고
    • Phase I trials of uraciltegafur (UFT) using 5 and 28 day administration schedules: demonstration of schedule-dependent toxicities
    • R Pazdur Y Lassere E Diaz-Canton Phase I trials of uraciltegafur (UFT) using 5 and 28 day administration schedules: demonstration of schedule-dependent toxicities Anticancer Drugs 7 1996 728 733
    • (1996) Anticancer Drugs , vol.7 , pp. 728-733
    • Pazdur, R1    Lassere, Y2    Diaz-Canton, E3
  • 35
    • 0000642139 scopus 로고    scopus 로고
    • Comparative steady state pharmacokinetics of oral UFT versus protracted intravenous 5-fluorouracil (5-FU)
    • R Pazdur W Covington Y Brown Comparative steady state pharmacokinetics of oral UFT versus protracted intravenous 5-fluorouracil (5-FU) Proc Am Soc Clin Oncol 15 1996 474 (Abstract #1498).
    • (1996) Proc Am Soc Clin Oncol , vol.15 , pp. 474
    • Pazdur, R1    Covington, W2    Brown, Y3
  • 36
    • 0000082787 scopus 로고    scopus 로고
    • Multicenter phase III study of 5-fluorouracil (5-FU) or UFTTM in combination with leucovorin (LV) in patients with metastatic colorectal cancer
    • R Pazdur J-Y Douillard J Skillings Multicenter phase III study of 5-fluorouracil (5-FU) or UFTTM in combination with leucovorin (LV) in patients with metastatic colorectal cancer Proc Am Soc Clin Oncol 18 1999 263a (Abstract #1009).
    • (1999) Proc Am Soc Clin Oncol , vol.18 , pp. 263a
    • Pazdur, R1    Douillard, J-Y2    Skillings, J3
  • 38
    • 18244414936 scopus 로고    scopus 로고
    • Phase I clinical and pharmacokinetic study of oral S-1 in patients with advanced solid tumors
    • CJ van Groeningen GJ Peters JH Schornagel Phase I clinical and pharmacokinetic study of oral S-1 in patients with advanced solid tumors J Clin Oncol 18 2000 2772 2779
    • (2000) J Clin Oncol , vol.18 , pp. 2772-2779
    • van Groeningen, CJ1    Peters, GJ2    Schornagel, JH3
  • 39
    • 0001100666 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic (PK) study of the novel oral fluoropyrimidine, S-1
    • P Hoff C Wenske D Medgyesy Phase I and pharmacokinetic (PK) study of the novel oral fluoropyrimidine, S-1 Proc Am Soc Clin Oncol 18 1999 173a (Abstract #665).
    • (1999) Proc Am Soc Clin Oncol , vol.18 , pp. 173a
    • Hoff, P1    Wenske, C2    Medgyesy, D3
  • 40
    • 0005630667 scopus 로고    scopus 로고
    • Late phase II study of S-1 in patients with advanced and/or recurrent breast cancer
    • M Sano T Saeki S Takashima Late phase II study of S-1 in patients with advanced and/or recurrent breast cancer Proc Am Soc Clin Oncol 19 2000 105a (Abstract #404).
    • (2000) Proc Am Soc Clin Oncol , vol.19 , pp. 105a
    • Sano, M1    Saeki, T2    Takashima, S3
  • 41
    • 0003296409 scopus 로고    scopus 로고
    • Early phase II study of S-1 in patients with advanced head and neck cancer
    • M Fujii J Kanzaki B Satake Early phase II study of S-1 in patients with advanced head and neck cancer Proc Am Soc Clin Oncol 15 1996 316 (Abstract #894).
    • (1996) Proc Am Soc Clin Oncol , vol.15 , pp. 316
    • Fujii, M1    Kanzaki, J2    Satake, B3
  • 42
    • 0001733294 scopus 로고    scopus 로고
    • Late phase III study of S-1 in patients with advanced colorectal cancer in Japan
    • H Baba A Ohtsu Y Sakata Late phase III study of S-1 in patients with advanced colorectal cancer in Japan Proc Am Soc Clin Oncol 17 1998 277a (Abstract #1065).
    • (1998) Proc Am Soc Clin Oncol , vol.17 , pp. 277a
    • Baba, H1    Ohtsu, A2    Sakata, Y3
  • 44
    • 0024819931 scopus 로고
    • Antitumor activity of BOF-A2, a new 5-fluorouracil derivative
    • S Fujii M Fukushima Y Shimamoto Antitumor activity of BOF-A2, a new 5-fluorouracil derivative Jpn J Cancer Res 80 1989 173 181
    • (1989) Jpn J Cancer Res , vol.80 , pp. 173-181
    • Fujii, S1    Fukushima, M2    Shimamoto, Y3
  • 45
    • 85120228771 scopus 로고    scopus 로고
    • Phase I trial of oral BOF-A2 plus leucovorin (LV) in advanced colorectal cancer (CRC): antitumor activity in fluorouracil-resistant patients
    • C Matei P Hoff R Brito Phase I trial of oral BOF-A2 plus leucovorin (LV) in advanced colorectal cancer (CRC): antitumor activity in fluorouracil-resistant patients Proc Am Soc Clin Oncol 17 1998 230a (Abstract #882).
    • (1998) Proc Am Soc Clin Oncol , vol.17 , pp. 230a
    • Matei, C1    Hoff, P2    Brito, R3
  • 46
    • 0000389059 scopus 로고    scopus 로고
    • Weekly irinotecan (CPT-11), leucovorin (LV), and fluorouracil (FU) is superior to daily × 5 LV/FU in patients (PTS) with previously untreated metastatic colorectal cancer (CRC)
    • L Saltz P Locker N Pirotta Weekly irinotecan (CPT-11), leucovorin (LV), and fluorouracil (FU) is superior to daily × 5 LV/FU in patients (PTS) with previously untreated metastatic colorectal cancer (CRC) Proc Am Soc Clin Oncol 18 1999 233a (Abstract #898).
    • (1999) Proc Am Soc Clin Oncol , vol.18 , pp. 233a
    • Saltz, L1    Locker, P2    Pirotta, N3
  • 47
    • 0001146335 scopus 로고    scopus 로고
    • Oxaliplatin (OXAL) or CPT-11 combined with 5FU/leucovorin (LV) in advanced colorectal cancer (CRC): an NCCTG/CALGB study
    • RF Morton RM Goldberg DJ Sargent Oxaliplatin (OXAL) or CPT-11 combined with 5FU/leucovorin (LV) in advanced colorectal cancer (CRC): an NCCTG/CALGB study Proc Am Soc Clin Oncol 20 2001 125a (Abstract #495).
    • (2001) Proc Am Soc Clin Oncol , vol.20 , pp. 125a
    • Morton, RF1    Goldberg, RM2    Sargent, DJ3
  • 48
    • 0003199012 scopus 로고    scopus 로고
    • Extended phase I study of capecitabine in combination with a weekly schedule of irinotecan as first-line chemotherapy in metastatic colorectal cancer
    • N Schleucher M Tewes W Achterrath Extended phase I study of capecitabine in combination with a weekly schedule of irinotecan as first-line chemotherapy in metastatic colorectal cancer Proc Am Soc Clin Oncol 20 2001 141a (Abstract #561).
    • (2001) Proc Am Soc Clin Oncol , vol.20 , pp. 141a
    • Schleucher, N1    Tewes, M2    Achterrath, W3
  • 49
    • 85120231280 scopus 로고    scopus 로고
    • Phase I-II trial of irinotecan (CPT-11) over a short IV weekly infusion combined with a fixed dose of UFT in second line advanced colorectal carcinoma (ACRC)
    • P Escudero A Vicente A Herrero Phase I-II trial of irinotecan (CPT-11) over a short IV weekly infusion combined with a fixed dose of UFT in second line advanced colorectal carcinoma (ACRC) Proc Am Soc Clin Oncol 19 2000 257a (Abstract #1136).
    • (2000) Proc Am Soc Clin Oncol , vol.19 , pp. 257a
    • Escudero, P1    Vicente, A2    Herrero, A3
  • 50
    • 0003287451 scopus 로고    scopus 로고
    • A phase I study of oral uracil/tegafur (UFT) plus leucovorin (LV) combined with oxaliplatin in patients with metastatic colorectal cancer (CRC)
    • JY Douillard JF Seitz A phase I study of oral uracil/tegafur (UFT) plus leucovorin (LV) combined with oxaliplatin in patients with metastatic colorectal cancer (CRC) Proc Am Soc Clin Oncol 20 2001 144a (Abstract #572).
    • (2001) Proc Am Soc Clin Oncol , vol.20 , pp. 144a
    • Douillard, JY1    Seitz, JF2
  • 51
    • 0000301005 scopus 로고    scopus 로고
    • Phase II study of capecitabine (CAP) + oxaliplatin (OXA) in first line and second line treatment of advanced or metastatic colorectal cancer (ACC)
    • MM Borner S Mueller A Roth Phase II study of capecitabine (CAP) + oxaliplatin (OXA) in first line and second line treatment of advanced or metastatic colorectal cancer (ACC) Proc Am Soc Clin Oncol 20 2001 137a (Abstract #546).
    • (2001) Proc Am Soc Clin Oncol , vol.20 , pp. 137a
    • Borner, MM1    Mueller, S2    Roth, A3


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