Effects of nonylphenol on estrogen receptor conformation, transcriptional activity and sexual reversion in rainbow trout (Oncorhynchus mykiss)

Aquatic Toxicology

Volumn 53, Issue 3-4, 2001, Pages 173-186

  Madigou, T ^a   Le Goff, P ^a   Salbert, G ^a   Cravedi, J P ^b   Segner, H ^c   Pakdel, F ^a   Valotaire, Y ^a  

^a UPRES A CNRS 6026   (France)

^b CEMAGREF   (France)

^c HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH UFZ   (Germany)

Author keywords

4 Nonylphenol; Estrogen receptor; Rainbow trout; Xenoestrogens

Indexed keywords

ESTROGEN RECEPTOR; NONYLPHENOL;

ANIMAL CELL; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; GONAD DEVELOPMENT; IN VITRO STUDY; LIVER CELL; MALE GENITAL SYSTEM; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAINBOW TROUT; SEX DIFFERENTIATION; TOXICITY TESTING; TRANSCRIPTION REGULATION; WATER POLLUTION; XENOBIOTIC METABOLISM; YEAST;

ANIMALS; FEMALE; MALE; ONCORHYNCHUS MYKISS; PHENOLS; PROTEIN CONFORMATION; RECEPTORS, ESTROGEN; SEX DIFFERENTIATION; TRANSCRIPTION, GENETIC;

MYKISS; ONCORHYNCHUS MYKISS; PISCES; SALMONIDAE;

EID: 0035427679     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-445X(01)00164-3     Document Type: Article

References (55)

1. Behaviour of alkylphenol polyethoxylate surfactants in the aquatic environment, II: occurrence and transformation in rivers
2. Hormone and antihormone induce distinct conformational changes which are central to steroid receptor activation
3. Transcriptional activation by the estrogen receptor requires a conformational change in the ligand-binding domain
4. Reproduction in rainbow trout: sex differentiation, dynamics of gametogenesis, biology and preservation of gametes
5. Structural and functional effects of early exposure to estradiol 17β- and 17α-ethynylestradiol on the gonads of the gonochoristic teleost Dicentrachus labrax
6. Molecular basis of agonism and antagonism in the œstrogen receptor
7. Interaction of proteins with transcriptionally active estrogen receptors
8. A reproducible microanalytical method for the detection of specific RNA sequence by dot-blot hybridization
9. Ligand-induced conformational change in the human mineralocorticoid receptor occurs within its hetero-oligomeric structure
10. Monolayer and aggregate cultures of rainbow trout hepatocytes: long-term and stable liver-specific expression in aggregates
11. Influence of xenobiotics on rainbow trout liver estrogen receptor and vitellogenin gene expression
12. 4-Nonylphenol in sewage sludge: accumulation of toxic metabolites from nonionic surfactants
13. Feminization of male carp
14. Bisphenol A interacts with estrogen receptor α in a distinct manner from estradiol
15. Induction of testis-ova in Japanese medaka (Oryzias latipes) exposed to n-nonlyphenol
16. Gonadal development in Japanese medaka (Oryzias latipes) exposed to 17β-estradiol
17. GRIP1, a transcriptional coactivator for the AF-2 transactivation domain of steroid, thyroid, retinoid and vitamin D receptors
18. Detergent components in sewage effluent are weakly oestrogenic to fish: an in vitro study using rainbow trout (Oncorhynchus mykiss) hepatocytes
19. Inhibition of testicular growth in rainbow trout (Oncorhynchus mykiss) exposed to alkylphenolic chemicals
20. Different agonist-induced and antagonist-induced conformational changes in retinoic acid receptors analyzed by protease mapping
21. Estrogen receptor binding to estrogen response elements slows ligand dissociation and synergistically activates reporter gene expression
22. Ligand-induced conformational alterations of the androgen receptor analyzed by limited trypsinization. Studies on the mechanism of antiandrogen action
23. Cooperation between the human estrogen receptor (ER) and MCF-7 cell-specific transcription factors elicits high activity of an estrogen-inducible enhancer from the trout ER gene promoter
24. The nuclear orphan receptors COUP-TF and ARP-1 positively regulate the trout estrogen receptor gene through enhancing autoregulation
25. In vivo estrogenic activity of nonylphenol in rainbow trout
26. Uptake, disposition, and persistence of nonylphenol from water in rainbow trout (Oncorhynchus mykiss)
27. Estradiol 17-β stimulation of vitellogenin synthesis in primary culture of male rainbow trout hepatocytes
28. Promoter specificity of the two transcriptional activation functions of the human œstrogen receptor in yeast
29. Alkylphenol ethoxylate in the environment
30. Different positioning of the ligand-binding domain helix 12 and the F domain of the estrogen receptor accounts for functional differences between agonists and antagonists
31. Reproduction and development of Japanes medaka following an early life stage exposure to xenoestrogens
32. Differential functional activities of rainbow trout and human estrogen receptor expressed in the yeast Saccharomyces cerevisiae
33. Two complementary bioassays for screening the estrogenic potency of xenobiotics: recombinant yeast for trout estrogen receptor and trout hepatocyte cultures
34. Trout estrogen receptor sensitivity to xenobiotics as tested by different bioassays
35. Synergism between a half-site and an imperfect estrogen-responsive element, and cooperation with COUP-TFI are required for estrogen receptor (ER) to achieve a maximal estrogen-stimulation of rainbow trout ER gene
36. Gonadal differentiation in coho salmon, Oncorhynchus kisutch, after a single treatment with androgen or estrogen at different stages during ontogenesis
37. Localization of the estradiol receptor mRNA in the forebrain of the rainbow trout
38. Preparation of rat liver cells II. Effects of ions and chelators on tissue dispersion
39. Thyroid hormone response elements differentially modulate the interactions of thyroid hormone receptors with two receptor binding domains in the steroid receptor coactivator-1
40. 3H]-4-n-nonylphenol in rainbow trout
41. Characterization of biliary metabolites of 4-n-nonylphenol in rainbow trout (Oncorhynchus mykiss)
42. Urinary metabolites of 4-n-nonylphenol in rainbow trout (Oncorhynchus mykiss)
43. Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose
44. Male reproductive health and environmental xenoœstrogens
45. The human estrogen receptor has two independent nonacidic transcriptional activation functions
46. Molecular mechanisms of action of steroid/thyroid receptor superfamily members
47. Human estrogen receptor transcriptional capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions
48. A morphological and experimental study of gonadalsex differentiation in the rainbow trout, Salmo gairdneri
49. TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors
50. Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1
51. Environmentally persistent alkylphenolic compounds are estrogenic
52. Structure-function analysis of the hormone binding domain of the human estrogen receptor by region-specific mutagenesis and phenotypic screening in yeast