Protection against glutamate toxicity through inhibition of the p44/42 mitogen-activated protein kinase pathway in neuronally differentiated P19 cells

Biochemical Pharmacology

Volumn 62, Issue 3, 2001, Pages 283-296

  Grant, Elfrida R ^a   Errico, Monica A ^a   Emanuel, Stuart L ^a   Benjamin, Daniel ^a   McMillian, Michael K ^a   Wadsworth, Scott A ^a   Zivin, Robert A ^a   Zhong, Zhong ^a,b  

^a R W JOHNSON PHARMACEUTICAL RES I   (United States)

^b Cell and Molecular Technologies   (United States)

Author keywords

Glutamate; N Methyl D aspartate; Neuroprotection; P44 42 MAP kinase; Phosphorylation; U0126

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; DIZOCILPINE; GLUTAMIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; RECEPTOR SUBUNIT;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; ENZYME PHOSPHORYLATION; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; PROTECTION; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BUTADIENES; CELL DIFFERENTIATION; DRUG INTERACTIONS; ENZYME INHIBITORS; GLUTAMIC ACID; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; N-METHYLASPARTATE; NEURONS; NEUROPROTECTIVE AGENTS; NITRILES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; RECEPTORS, N-METHYL-D-ASPARTATE; TUMOR CELLS, CULTURED;

EID: 0035427631     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00665-7     Document Type: Article

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