메뉴 건너뛰기




Volumn 22, Issue 7, 2001, Pages 361-368

Therapeutic implications of human endothelial nitric oxide synthase gene polymorphism

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CYSTEINE; GLYCINE; ISOPROTEIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; THREONINE;

EID: 0035398540     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(00)01692-8     Document Type: Review
Times cited : (95)

References (57)
  • 4
    • 0032567415 scopus 로고    scopus 로고
    • In situ flow activates endothelial nitric oxide synthase in luminal caveolae of endothelium with rapid caveolin dissociation and calmodulin association
    • (1998) J. Biol. Chem. , vol.273 , pp. 34724-34729
    • Rizzo, V.1
  • 5
    • 0027183208 scopus 로고
    • Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene
    • (1993) J. Biol. Chem. , vol.268 , pp. 17478-17488
    • Marsden, P.A.1
  • 6
    • 0031902667 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase gene is positively associated with essential hypertension
    • (1998) Hypertension , vol.32 , pp. 3-8
    • Miyamoto, Y.1
  • 7
    • 0034070324 scopus 로고    scopus 로고
    • High CA repeat numbers in intron 13 of the endothelial nitric oxide synthase gene and increased risk of coronary artery disease
    • (2000) Pharmacogenetics , vol.10 , pp. 133-140
    • Stangl, K.1
  • 9
    • 0033535841 scopus 로고    scopus 로고
    • T-786>C mutation in the 5′-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm
    • (1999) Circulation , vol.99 , pp. 2864-2870
    • Nakayama, M.1
  • 10
    • 0032164051 scopus 로고    scopus 로고
    • MspI polymorphism in the promoter of the human endothelial constitutive NO synthase gene in Australian Caucasian population
    • (1998) Mol. Genet. Metab. , vol.65 , pp. 62
    • Sim, A.S.1
  • 11
    • 0031659845 scopus 로고    scopus 로고
    • A missense Glu298Asp variant in the endothelial nitric oxide synthase gene is associated with coronary spasm in the Japanese
    • (1998) Hum. Genet. , vol.103 , pp. 65-69
    • Yoshimura, M.1
  • 12
    • 0031748762 scopus 로고    scopus 로고
    • Association of the missense Glu298Asp variant of the endothelial nitric oxide synthase gene with myocardial infarction
    • (1998) J. Am. Coll. Cardiol. , vol.31 , pp. 1506-1510
    • Shimasaki, Y.1
  • 13
    • 0034646248 scopus 로고    scopus 로고
    • Intracellular processing of endothelial nitric oxide synthase isoforms associated with differences in severity of cardiopulmonary diseases: Cleavage of proteins with aspartate vs. glutamate at position 298
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 2832-2835
    • Tesauro, M.1
  • 14
    • 0033669591 scopus 로고    scopus 로고
    • Functional gene testing of the Glu298Asp polymorphism of the endothelial NO synthase
    • (2000) J. Hypertens. , vol.18 , pp. 1767-1773
    • Schneider, M.P.1
  • 15
    • 0032952468 scopus 로고    scopus 로고
    • Freely associating
    • (1999) Nat. Genet. , vol.22 , pp. 1-2
  • 16
    • 0007932349 scopus 로고    scopus 로고
    • Interpretation of results from genetic studies of multifactorial diseases
    • (1999) Lancet , vol.354
    • Todd, J.A.1
  • 18
    • 0029151307 scopus 로고
    • CA repeat polymorphism of the endothelial nitric oxide synthase gene in the Japanese
    • (1995) Hum. Hered. , vol.45 , pp. 301-302
    • Nakayama, T.1
  • 19
    • 0032717816 scopus 로고    scopus 로고
    • The relationship between polymorphisms in the endothelial cell nitric oxide synthase gene and the platelet GPIIIa gene with myocardial infarction and venous thromboembolism in African Americans
    • (1999) Chest , vol.116 , pp. 880-886
    • Hooper, W.C.1
  • 20
    • 0033966101 scopus 로고    scopus 로고
    • Endothelial dysfunction and peroxynitrite formation are early events in angiotensin-induced cardiovascular disorders
    • (2000) FASEB J. , vol.14 , pp. 271-278
    • Wattanapitayakul, S.K.1
  • 21
    • 0031813165 scopus 로고    scopus 로고
    • Association of extracellular-superoxide dismutase phenotype with the endothelial constitutive nitric oxide synthase polymorphism
    • (1998) FEBS Lett. , vol.433 , pp. 166-168
    • Adachi, T.1    Wang, X.L.2
  • 23
    • 0032696776 scopus 로고    scopus 로고
    • A multilocus genotyping assay for candidate markers of cardiovascular disease risk
    • (1999) Genome Res. , vol.9 , pp. 936-949
    • Cheng, S.1
  • 24
    • 0033629838 scopus 로고    scopus 로고
    • Aging affects the association between endothelial nitric oxide synthase gene polymorphism and acute myocardial infarction in the Korean male population
    • (2000) Korean J. Int. Med. , vol.15 , pp. 65-70
    • Park, J.E.1
  • 25
    • 0030048029 scopus 로고    scopus 로고
    • A smoking-dependent risk of coronary artery disease associated with a polymorphism of the endothelial nitric oxide synthase gene
    • (1996) Nat. Med. , vol.2 , pp. 41-45
    • Wang, X.L.1
  • 26
    • 0034616273 scopus 로고    scopus 로고
    • Genotype dependent and cigarette specific effects on endothelial nitric oxide synthase gene expression and enzyme activity
    • (2000) FEBS Lett. , vol.471 , pp. 45-50
    • Wang, X.L.1
  • 27
    • 0028795150 scopus 로고
    • Lack of evidence for linkage of the endothelial cell nitric oxide synthase gene to essential hypertension
    • (1995) Circulation , vol.91 , pp. 96-102
    • Bonnardeaux, A.1
  • 28
    • 0031916030 scopus 로고    scopus 로고
    • Nitric oxide synthase gene polymorphisms, blood pressure and aortic stiffness in normotensive and hypertensive subjects
    • (1998) J. Hypertens. , vol.16 , pp. 31-35
    • Lacolley, P.1
  • 29
    • 0032923082 scopus 로고    scopus 로고
    • Dinucleotide repeat polymorphisms in EDN1 and NOS3 are not associated with severe diabetic retinopathy in type 1 or type 2 diabetes
    • (1999) Eye , vol.13 , pp. 174-178
    • Warpeha, K.M.1
  • 30
    • 0030840581 scopus 로고    scopus 로고
    • Migraine association and linkage studies of an endothelial nitric oxide synthase (nos3) gene polymorphism
    • (1997) Neurology , vol.49 , pp. 614-617
    • Griffiths, L.R.1
  • 31
    • 0031057938 scopus 로고    scopus 로고
    • Association analysis of CA repeat polymorphism of the endothelial nitric oxide synthase gene with essential hypertension in Japanese
    • (1997) Clin. Genet. , vol.51 , pp. 26-30
    • Nakayama, T.1
  • 33
    • 0031918997 scopus 로고    scopus 로고
    • Association of a variable number of tandem repeats in the endothelial constitutive nitric oxide synthase gene with essential hypertension in Japanese
    • (1998) Am. J. Hypertens. , vol.11 , pp. 125-128
    • Uwabo, J.1
  • 35
    • 0034043152 scopus 로고    scopus 로고
    • Lack of association between 27-bp repeat polymorphism in intron 4 of the endothelial nitric oxide synthase gene and the risk of coronary artery disease
    • (2000) Scand. J. Clin. Lab. Invest. , vol.60 , pp. 229-235
    • Sigusch, H.H.1
  • 36
    • 0032723134 scopus 로고    scopus 로고
    • Coronary artery disease and endothelial nitric oxide synthase and angiotensin-converting enzyme gene polymorphisms
    • (1999) J. Thromb. Thrombolysis , vol.8 , pp. 191-195
    • Nakagami, H.1
  • 37
    • 0031780310 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase gene polymorphism and coronary heart disease in Japanese NIDDM
    • (1998) Diabetologia , vol.41 , pp. 365-366
    • Odawara, M.1
  • 38
    • 0031704975 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase gene polymorphism and acute myocardial infarction
    • (1998) Hypertension , vol.32 , pp. 521-526
    • Hibi, K.1
  • 39
    • 0031984045 scopus 로고    scopus 로고
    • Association of a polymorphism of the endothelial constitutive nitric oxide synthase gene with myocardial infarction in the Japanese population
    • (1998) Am. J. Cardiol. , vol.81 , pp. 83-86
    • Ichihara, S.1
  • 40
    • 0030819221 scopus 로고    scopus 로고
    • Gene-polymorphisms of angiotensin converting enzyme and endothelial nitric oxide synthase in patients with primary glomerulonephritis
    • (1997) Clin. Nephrol. , vol.48 , pp. 205-211
    • Burg, M.1
  • 41
    • 0032858068 scopus 로고    scopus 로고
    • Effect of a polymorphism of endothelial nitric oxide synthase gene in Japanese patients with IgA nephropathy
    • (1999) Clin. Nephrol. , vol.52 , pp. 203-209
    • Morita, T.1
  • 42
    • 0031833811 scopus 로고    scopus 로고
    • High accumulation of endothelial nitric oxide synthase (ecNOS): A gene polymorphism in patients with end-stage renal disease
    • (1998) Nephron , vol.79 , pp. 360-361
    • Yokoyama, K.1
  • 43
    • 0032841549 scopus 로고    scopus 로고
    • Relationship between erythropoietin administration and the endothelial nitric oxide synthase gene polymorphism in patients with hemodialysis
    • (1999) Nephron , vol.82 , pp. 354-355
    • Yokoyama, K.1
  • 44
    • 0031847438 scopus 로고    scopus 로고
    • The 27-bp repeat polymorphism in intron 4 of the endothelial cell nitric oxide synthase gene and ischemic stroke in a Japanese population
    • (1998) Blood Coagul. Fibrinolysis , vol.9 , pp. 405-409
    • Yahashi, Y.1
  • 45
    • 0033119777 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase intron 4, 27 bp repeat polymorphism in Turkish patients with deep vein thrombosis and cerebrovascular accidents
    • (1999) Thromb. Res. , vol.94 , pp. 63-64
    • Akar, N.1
  • 46
    • 0033850271 scopus 로고    scopus 로고
    • Genetic risk factors for coronary artery spasm: Significance of endothelial nitric oxide synthase gene T786C and missense Glu298Asp variants
    • (2000) J. Invest. Med. , vol.48 , pp. 367-374
    • Yoshimura, M.1
  • 47
    • 0345192295 scopus 로고    scopus 로고
    • A common variant of the endothelial nitric oxide synthase (Glu298Asp) is a major risk factor for coronary artery disease in the UK
    • (1999) Circulation , vol.100 , pp. 1515-1520
    • Hingorani, A.D.1
  • 48
    • 0032586925 scopus 로고    scopus 로고
    • The Glu298Asp (G894T) mutation at exon 7 of the endothelial nitric oxide synthase gene and coronary artery disease
    • (1999) J. Mol. Med. , vol.77 , pp. 511-514
    • Cai, H.1
  • 49
    • 0033850271 scopus 로고    scopus 로고
    • Genetic risk factors for coronary artery spasm: Significance of endothelial nitric oxide synthase gene T786C and missense Glu298Asp variants
    • (2000) J. Invest. Med. , vol.48 , pp. 367-374
    • Yoshimura, M.1
  • 50
    • 0032890548 scopus 로고    scopus 로고
    • Lack of evidence for association between the endothelial nitric oxide synthase gene and hypertension
    • (1999) Hypertension , vol.33 , pp. 933-936
    • Kato, N.1
  • 51
    • 0012266389 scopus 로고    scopus 로고
    • Positive association of endothelial nitric oxide synthase gene polymorphism with hypertension in northern Japan
    • (2000) Life Sci. , vol.66 , pp. 2557-2562
    • Shoji, M.1
  • 52
    • 0000164602 scopus 로고    scopus 로고
    • Polymorphisms of the endothelial nitric oxide synthase gene - No consistent association with myocardial infarction in the ECTIM study
    • (1999) Eur. J. Clin. Invest. , vol.29 , pp. 284-290
    • Poirier, O.1
  • 53
    • 0034622202 scopus 로고    scopus 로고
    • Association of the missense Glu298Asp variant of the endothelial nitric oxide synthase gene with severe preeclampsia
    • (2000) J. Soc. Gynecol. Invest. , vol.7 , pp. 238-241
    • Yoshimura, T.1
  • 54
    • 4243270333 scopus 로고    scopus 로고
    • The Asp298 variant of endothelial nitric oxide synthase (eNOS) improves survival in patients with heart failure
    • (1999) Circulation , vol.100
    • McNamara, D.M.1
  • 55
    • 0031711925 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase exon 7 polymorphism, ischemic cerebrovascular disease, and carotid atheroma
    • (1998) Stroke , vol.29 , pp. 1908-1911
    • Markus, H.S.1
  • 56
    • 0033595221 scopus 로고    scopus 로고
    • No association between Glu/Asp polymorphism of NOS3 gene and ischemic stroke
    • (1999) Neurology , vol.53 , pp. 418-420
    • MacLeod, M.J.1
  • 57
    • 0033838034 scopus 로고    scopus 로고
    • No association between Glu/Asp polymorphism of NOS3 gene and ischemic stroke
    • (2000) Neurology , vol.55 , pp. 460-461
    • Akar, N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.