The role of protein kinase C in the biochemical pathways of classical conditioning

Neurocomputing

Volumn 38-40, Issue , 2001, Pages 79-85

  Yang, Keun Hang ^a   Hellgren Kotaleski, Jeanette ^b   Blackwell, Kim T ^a,b  

^a George Mason University   (United States)

^b GEORGE MASON UNIVERSITY   (United States)

Author keywords

Arachidonic acid (AA); Classical conditioning; Diacylglycerol (DAG); Protein kinase C (PKC) activation

Indexed keywords

BIOCHEMISTRY; COMPUTER SIMULATION; ENZYMES; FIBERS;

BIOCHEMICAL PATHWAYS;

NEUROLOGY;

ARACHIDONIC ACID; CALCIUM ION; DIACYLGLYCEROL; PROTEIN KINASE C;

ARTICLE; CEREBELLUM; CHEMICAL REACTION; CLIMBING FIBER; CONDITIONED REFLEX; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME SPECIFICITY; LONG TERM MEMORY; MEMORY CONSOLIDATION; NERVE STIMULATION; PRIORITY JOURNAL; SECOND MESSENGER; SENSITIVITY ANALYSIS; SIMULATION; STATISTICAL MODEL;

EID: 0035384092     PISSN: 09252312     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-2312(01)00488-X     Document Type: Article

References (20)

1. U.S. Bhalla, R. Iyengar, Emergent properties of networks of biological signaling pathways, Science 283 (1999) 381-387.
2. E. De Schutter, J.M. Bower, An active membrane model of the cerebellar Purkinje cell, I. Simulations of Current Clamps in Slice, J. Neurophysiol. 71 (1994a) 375-400.
3. E. De Schutter, J.M. Bower, An active membrane model of the cerebellar Purkinje cell, II. Simulation of synaptic responses, J. Neurophysiol. 71 (1994b) 401-419.
4. J.H. Freeman Jr., A.M. Scharenberg, J.L. Olds, B.G. Schreurs, Classical conditioning increases membrane-bound protein kinase C in rabbit cerebellum, Neuroreport 9 (1998) 2669-2673.
5. 2+, Neuroreport 9 (1998) 2237-2241.
6. D.S. Lester, C.R. Bramham, Persistent, membrane-associated protein kinase C: from model membranes to synaptic long-term potentiation, Cell Signal. 5 (1993) 695-708.
7. D.S. Lester, C. Collin, R. Etcheberrigaray, D.L. Alkon, Arachidonic acid and diacylglycerol act synergistically to activate protein kinase C in vitro and in vivo, Biochem. Biophys. Res. Commun. 179 (1991) 1522-1528.
8. D.J. Linden, J.A. Connor, Participation of postsynaptic PKC in cerebellar long-term depression in culture, Science 254 (1991) 1656-1659.
9. S. Mukhopadhyay, E.M. Ross, Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins, Proc. Natl. Acad. Sci. USA 96 (1999) 9539-9544.
10. Y. Nishizuka, Studies and prospectives of protein kinase C in signal transduction, Nippon Ketsueki Gakkai Zasshi 51 (1988) 1321-1326.
11. E. Oancea, T. Meyer, Protein kinase C as a molecular machine for decoding calcium and diacylglycerol signals, Cell 95 (1998) 307-318.
12. J.L. Olds, M.L. Anderson, D.L. McPhie, L.D. Staten, D.L. Alkon, Imaging of memory-specific changes in the distribution of protein kinase C in the hippocampus, Science 245 (1989) 866-869.
13. K. Petit, B. Miserez, J. De Block, G. Van Dessel, W. De Potter, The presence of phospholipase A2 in bovine adrenal medulla: arguments for more than one type of phospholipase A2, Biochim. Biophys. Acta. 1125 (1992) 150-156.
14. J.B. Schachter, D.S. Lester, D.L. Alkon, Synergistic activation of protein kinase C by arachidonic acid and diacylglycerols in vitro: generation of a stable membrane-bound, cofactor-independent state of protein kinase C activity, Biochim. Biophys. Acta. 1291 (1996) 167-176.
15. B.G. Schreurs, M.M. Oh, D.L. Alkon, Pairing-specific long-term depression of Purkinje cell excitatory postsynaptic potentials results from a classical conditioning procedure in the rabbit cerebellar slice, J. Neurophy. 75 (1996) 1051-1059.
16. Y. Shirai, K. Kashiwagi, K. Yagi, N. Sakai, N. Saito, Distinct effects of fatty acids on translocation of gamma- and epsilon-subspecies of protein kinase, J. Cell Biol. 143 (1998) 511-521.
17. A.V. Smrcka, J.R. Hepler, K.O. Brown, P.C. Sternweis, Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq, Science 251 (1991) 804-807.
18. 2, J. Neurosci. 15 (1995) 3307-3317.
19. F. Tempia, M.C. Miniaci, D. Anchisi, P. Strata, Postsynaptic current mediated by metabotropic glutamate receptors in cerebellar Purkinje cells, J. Neurophysiol. 80 (1998) 520-528.
20. K.-H. Yang, Potassium channels and PKC activation underlying temporal specificity of classical conditioning, Ph.D. Thesis, School of Computational Sciences, George Mason University, 2000.