Circular permutation of 5-aminolevulinate synthase: Mapping the polypeptide chain to its function

Journal of Biological Chemistry

Volumn 276, Issue 22, 2001, Pages 19141-19149

  Cheltsov, Anton V ^a   Barber, Michael J ^a,b   Ferreira, Gloria C ^a,b,c  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

^c H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CLONING; ENZYME KINETICS; PLANTS (BOTANY); POLYPEPTIDES;

ACTIVE SITES;

BIOCHEMISTRY;

5 AMINOLEVULINATE SYNTHASE; AMINO ACID; GLYCINE; PEPTIDE LIBRARY; POLYPEPTIDE; PYRIDOXAL 5 PHOSPHATE; CIRCULAR DNA; COMPLEMENTARY DNA; PEPTIDE;

ARTICLE; BINDING SITE; BIOSYNTHESIS; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBUNIT; MOLECULAR CLONING; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN SECONDARY STRUCTURE; SITE DIRECTED MUTAGENESIS; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CIRCULAR DICHROISM; KINETICS; METABOLISM; MOUSE; PLASMID; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; SPECTROPHOTOMETRY; ULTRAVIOLET RADIATION;

EUKARYOTA; PROKARYOTA;

5-AMINOLEVULINATE SYNTHETASE; ANIMALS; BINDING SITES; CIRCULAR DICHROISM; DNA, CIRCULAR; DNA, COMPLEMENTARY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; KINETICS; MICE; MODELS, MOLECULAR; PEPTIDE LIBRARY; PEPTIDES; PLASMIDS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SPECTROPHOTOMETRY; ULTRAVIOLET RAYS;

EID: 0035378483     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100329200     Document Type: Article

References (52)

1. Ferreira, G. C., and Gong, J. (1995) J. Bioenerg. Biomembr. 27, 151-159
2. Ferreira, G. C. (1999) in Inorganic Biochemistry and Regulatory Mechanisms of Iron Metabolism (Ferreira, G. C., Moura, J. J. G., and Franco, R., eds) pp. 15-34, Wiley-VCH, Weinheim, Germany
3. Sadlon, T. J., Dell'Oso, T., Surinya, K. H., and May, B. K. (1999) Int. J. Biochem. Cell Biol. 31, 1153-1167
4. Nakajima, O., Takahashi, S., Harigae, H., Furuyama, K., Hayashi N., Sassa, S., and Yamamoto, M. (1999) EMBO J. 18, 6282-6289
5. Cotter, P. D., Willard, H. F., Gorski, J. L., and Bishop, D. F. (1992) Genomics 13, 211-213
6. Bishop, D. F., Henderson, A. S., and Astrin, K. H. (1990) Genomics 7, 207-214
7. Bottomley, S. S. (1999) in Wintrobe's Clinical Hematology (Lee, G. R., ed) pp. 1022-1045, Lippincott Williams & Wilkins, Baltimore
8. Bottomley, S. S., May, B. K., Cox, T. C., Cotter, P. D., and Bishop, D. F. (1995) J. Bioenerg. Biomembr. 27, 161-168
9. Cotter, P. D., May, A., Li, L., Al-Sabah, A. I., Fitzsimons, E. J., Cazzola, M., and Bishop, D. F. (1999) Blood 93, 1757-1769
10. Harigae, H., Furuyama, K., Kimura, A., Neriishi, K., Tahara, N., Kondo, M., Hayashi, N., Yamamoto, M., Sassa, S., and Sasaki, T. (1999) Br. J. Haematol. 106, 175-177
11. Tan, D., and Ferreira, G. C. (1996) Biochemistry 35, 8934-8941
12. Ferreira, G. C., Neame, P. J., and Dailey, H. A. (1993) Protein Sci. 2, 1959-1965
13. Ferreira, G. C., Vajapey, U., Hafez, O., Hunter, G. A., and Barber, M. J. (1995) Protein Sci. 4, 1001-1006
14. Hunter, G. A., and Ferreira, G. C. (1999) Biochemistry 38, 3711-3718
15. Fanica-Gaignier, M., and Clement-Metral, J. (1973) Eur. J. Biochem. 40, 19-24
16. John, R. A. (1995) Biochim. Biophys. Acta 1248, 81-96
17. Ferreira, G. C. (2000) in Biochemistry and Molecular Biology of Vitamin B6 and PQQ-dependent Proteins (Iriarte, A., Kagan, H. M., and Martinez-Carrion, M. M., eds) pp. 257-263, Birkhauser Verlag, Basel
18. Hunter, G. A., and Ferreira, G. C. (1999) J. Biol. Chem. 274, 12222-12228
19. Tan, D., Harrison, T., Hunter, G. A., and Ferreira, G. C. (1998) Biochemistry 37, 1478-1484
20. Gong, J., Hunter, G. A., and Ferreira, G. C. (1998) Biochemistry 37, 3509-3517
21. Tan, D., Barber, M. J., and Ferreira, G. C. (1998) Protein Sci. 7, 1208-1213
22. Zhang, T., Bertelsen, E., Benvegnu, D., and Alber, T. (1993) Biochemistry 32, 12311-12318
23. Nakamura, T., and Iwakura, M. (1999) J. Biol. Chem. 274, 19041-19047
24. Goldenberg, D. P., and Creighton, T. E. (1983) J. Mol. Biol. 165, 407-413
25. Rote, K. V., Hough, R., Goldenberg, D., and Rechsteiner, M. C. (1989) J. Biol. Chem. 264, 1156-1162
26. Uversky, V. N., Kutyshenko, V. P., Protasova, N., Rogov, V. V., Vassilenko, K. S., and Gudkov, A. T. (1996) Protein Sci. 5, 1844-1851
27. Graf, R., and Schachman, H. K. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 11591-11596
28. Hennecke, J., Sebbel, P., and Glockshuber, R. (1999) J. Mol. Biol. 286, 1197-1215
29. Hennecke, J., and Glockshuber, R. (1998) Biochemistry 37, 17590-17597
30. Gutknecht, R., Manni, M., Mao, Q., and Erni, B. (1998) J. Biol. Chem. 273, 25745-25750
31. Zhang, P., and Schachman, H. K. (1996) Protein Sci. 5, 1290-1300
32. Li, J. M., Brathwaite, O., Cosloy, S. D., and Russell, C. S. (1989) J. Bacteriol. 171, 2547-2552
33. Huala, E., Moon, A. L., and Ausubel, F. M. (1991) J. Bacteriol. 173, 382-390
34. Ferreira, G. C., and Dailey, H. A. (1993) J. Biol. Chem. 268, 584-590
35. Sanger, F., Nicklen, S., and Coulson, A. R. (1977) Proc. Natl. Acad. Sci. U. S. A. 74, 5463-5467
36. Laemmli, U. K. (1970) Nature 227, 680-685
37. Gabriel, D. (1971) Methods Enzymol. 22, 568-578
38. Chen, G. C., and Yang, J. T. (1977) Anal. Lett. 10, 1195-1207
39. Hunter, G. A., and Ferreira, G. C. (1995) Anal. Biochem. 226, 221-224
40. Alexeev, D., Alexeeva, M., Baxter, R. L., Campopiano, D. J., Webster, S. P., and Sawyer, L. (1998) J. Mol. Biol. 284, 401-419
41. Webster, S. P., Alexeev, D., Campopiano, D. J., Watt, R. M., Alexeeva, M., Sawyer, L., and Baxter, R. L. (2000) Biochemistry 39, 516-528
42. Guex, N., and Peitsch, M. C. (1997) Electrophoresis 18, 2714-2723
43. Peitsch, M. C. (1996) Biochem. Soc. Trans. 24, 274-279
44. Peitsch, M. C. (1995) Bio/Technology 13, 658-660
45. Sternberg, M. J., and Thornton, J. M. (1977) J. Mol. Biol. 110, 269-283
46. Flores, T. P., Moss, D. S., and Thornton, J. M. (1994) Protein Eng. 7, 31-37
47. Garnier, J., Gibrat, J. F., and Robson, B. (1996) Methods Enzymol. 266, 540-553
48. Vriend, G. (1990) J. Mol. Graphics 8, 52-56
49. Hahn, M., Piotukh, K., Borriss, R., and Heinemann, U. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 10417-10421
50. Viguera, A. R., Blanco, F. J., and Serrano, L. (1995) J. Mol. Biol. 247, 670-681
51. Buchwalder, A., Szadkowski, H., and Kischner, K. (1992) Biochemistry 31, 1621-1630
52. Munakata, H., Yamagami, T., Nagai, T., Yamamoto, M., and Hayashi, N. (1993) J. Biochem. (Tokyo) 114, 103-111