Heme deficiency in erythroid lineage causes differentiation arrest and cytoplasmic iron overload

EMBO Journal

Volumn 18, Issue 22, 1999, Pages 6282-6289

  Nakajima, Osamu ^c   Takahashi, Satoru ^c   Harigae, Hideo ^a   Furuyama, Kazumichi ^a   Hayashi, Norio ^a   Sassa, Shigeru ^b   Yamamoto, Masayuki ^c  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b ROCKEFELLER UNIVERSITY   (United States)

^c UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

ALAS E; Heme; Iron metabolism; Transferrin receptors; X linked sideroblastic anemia

Indexed keywords

5 AMINOLEVULINATE SYNTHASE; HEME; IRON; ISOENZYME; TRANSFERRIN RECEPTOR;

ANIMAL CELL; ARTICLE; BIOSYNTHESIS; CATALYSIS; CELL DIFFERENTIATION; CELL FRACTIONATION; CELL LEVEL; CELL LINEAGE; CELL MUTANT; CONTROLLED STUDY; CYTOPLASM; EMBRYO; EMBRYO DEATH; ERYTHROID CELL; GENE DISRUPTION; GENE MUTATION; GENE STRUCTURE; GENE TARGETING; GENOTYPE; HEMATOPOIESIS; HEME SYNTHESIS; IRON METABOLISM; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIDEROBLASTIC ANEMIA; X CHROMOSOME LINKAGE;

5-AMINOLEVULINATE SYNTHETASE; ANIMALS; CELL DIFFERENTIATION; CHIMERA; CYTOPLASM; EMBRYONIC AND FETAL DEVELOPMENT; ERYTHROID PROGENITOR CELLS; ERYTHROPOIESIS; FEMALE; FETAL DEATH; FLOW CYTOMETRY; GENOTYPE; HEME; HUMANS; IRON; ISOENZYMES; MALE; MICE; MICE, KNOCKOUT;

ANIMALIA;

EID: 0033571237     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.22.6282     Document Type: Article

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