Primate anterior cingulate cortex: Where motor control, drive and cognition interface

Nature Reviews Neuroscience

Volumn 2, Issue 6, 2001, Pages 417-424

  Paus, Tomáš ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

PRIMATES;

ANIMAL; AROUSAL; BRAIN INJURY; CINGULATE GYRUS; COGNITION; DRIVE; HISTOLOGY; HUMAN; MOVEMENT (PHYSIOLOGY); PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PRIMATE; REVIEW;

ANIMALS; AROUSAL; BRAIN INJURIES; COGNITION; DRIVE; GYRUS CINGULI; HUMANS; MOVEMENT; PRIMATES; VOLITION;

EID: 0035375091     PISSN: 14710048     EISSN: None     Source Type: Journal    
DOI: 10.1038/35077500     Document Type: Review

References (110)

1. Paus, T. et al. Human cingulate and paracingulate sulci: pattern, variability, asymmetry, and probabilistic map. Cereb. Cortex 6, 207-214 (1996).
2. Ide, A. et al. Hemispheric differences in variability of fissural patterns in parasylvian and cingulate regions of human brains. J. Comp. Neurol. 410, 235-242 (1999).
3. Yucel, M. et al. Hemispheric and gender-related differences in the gross morphology of the anterior cingulate/paracingulate cortex in normal volunteers: an MRI morphometric study. Cereb. Cortex 11, 17-25 (2001).
4. Paus, T. et al. In-vivo morphometry of the intrasulcal gray-matter in the human cingulate, paracingulate and superiorrostral sulci: hemispheric asymmetries and gender differences. J. Comp. Neurol. 376, 664-673 (1996).
5. Crosson, B. et al. Activity in the paracingulate and cingulate sulci during word generation: an fMRI study of functional anatomy. Cereb. Cortex 9, 307-316 (1999).
6. Barbas, H. & Pandya, D. N. Architecture and intrinsic connections of the prefrontal cortex in the rhesus monkey. J. Comp. Neurol. 286, 353-375 (1989). An evolutionary perspective on cyto-and myelo-architecture and cortico-cortical connectivity of the monkey prefrontal cortex, including the cingulate cortex.
7. Barbas, H. in The Association Cortex: Structure and Function (eds Sakata, H., Mikami, A. & Fuster, J.) 99-116 (Harwood Academic, Amsterdam, 1997).
8. Bates, J. F. & Goldman-Rakic, P. S. Prefrontal connections of medial motor areas in the rhesus monkey. J. Comp. Neurol. 336, 211-228 (1993).
9. Morecraft, R. J. & Van Hoesen, G. W. Frontal granular cortex input to the cingulate (M3), supplementary (M2) and primary (M1) motor cortices in the rhesus monkey. J. Comp. Neurol. 337, 669-689 (1993).
10. Picard, N. & Strick, P. L. Motor areas of the medial wall: a review of their location and functional activation. Cereb. Cortex 6, 342-353 (1996).
11. Dum, R. P. & Strick, P. L. The origin of corticospinal projections from the premotor areas in the frontal lobe. J. Neurosci. 11, 667-689 (1991). A landmark study on the organization of corticospinal projections in the monkey lateral and medial frontal cortex.
12. Morecraft, R. J. & Van Hoesen, G. W. Cingulate input to the primary and supplementary motor cortices in the rhesus monkey: evidence for somatotopy in areas 24c and 23c. J. Comp. Neurol. 322, 471-489 (1992).
13. An, X., Bandler, R., Ongur, D. & Price, J. Prefrontal cortical projections to longitudinal columns in the midbrain periaqueductal grey in macaque monkeys. J. Comp. Neurol. 401, 455-479 (1998).
14. Morecraft, R. J., Geula, C. & Mesulam, M. M. Architecture of connectivity within a cingulo-fronto-parietal neurocognitive network for directed attention. Arch. Neurol. 50, 279-284 (1993).
15. Müller-Preuss, P. & Jürgens, U. Projections from the 'cingular' vocalization area in the squirrel monkey. Brain Res. 103, 29-43 (1976).
16. Jürgens, U. Projections from the cortical larynx area in the squirrel monkey. Exp. Brain Res. 25, 401-411 (1976).
17. Jürgens, U. Afferent fibers to the cingular vocalization region in the squirrel monkey. Exp. Neurol. 80, 395-409 (1983).
18. Vogt, B. A. & Barbas, H. in The Physiological Control of Mammalian Vocalization (ed. Newman, J. D.) 203-225 (Plenum,NewYork, 1988).
19. Barbas, H., Ghashghaei, H., Dombrowski, S. M. & Rempel-Clower, N. L Medial prefrontal cortices are unified by common connections with superior temporal cortices and distinguished by input from memory-related areas in the rhesus monkey. J. Comp. Neurol. 410, 343-367 (1999).
20. Barbas, H. & De Olmos, J. Projections from the amygdala to basoventral and mediodorsal prefrontal regions in the rhesus monkey. J. Comp. Neurol. 301, 1-23 (1990).
21. Kunishio, K. & Haber, S. Primate cingulostriatal projection: limbic striatal versus sensorimotor striatal input. J. Comp. Neurol. 350, 337-356 (1994).
22. Morecraft, R. J. & Van Hoesen, G. W. Convergence of limbic input to the cingulate motor cortex in the rhesus monkey. Brain Res. Bull. 45, 209-232 (1998). An account of the intrinsic connectivity of the dorsal and ventral tiers of the monkey cingulate cortex.
23. Barbas, H., Henion, T.H. & Dermon, C. R. Diverse thalamic projections to the prefrontal cortex in the rhesus monkey. J. Comp. Neurol. 313, 65-94 (1991).
24. Montaron, M.-F. & Buser, P. Relationships between nucleus medialis dorsalis, pericruciate cortex, ventral tegmental area and nucleus accumbens in cat: an electrophysiological study. Exp. Brain Res. 69, 559-566 (1988).
25. Berger, B. in Advances in Neurology Vol. 57 (eds Chauvel, P. & Delgado-Escueta, A. V.) 525-544 (Raven, New York, 1992). Comparative neurochemical analysis of the frontal cortex, with special emphasis on the dopamine innervation of the primary motor cortex, lateral prefrontal cortex and the anterior cingulate cortex.
26. Crino, P. B., Morrison, J. H. & Hof, P. R. in Neurobiology of Cingulate Cortex and Limbic Thalamus: a Comprehensive Handbook (eds Vogt, B. A. & Gabriel, M.) 285-299 (Birkhäuser, Boston, 1993).
27. Gaspar, P., Berger, B., Febvret, A., Vigny, A. & Henry, J. P. Catecholamine innervation of the human cerebral cortex as revealed by comparative immunohistochemistry of tyrosine hydroxylase and dopamine-β-hydroxylase. J. Comp. Neurol. 279, 249-271 (1989). The first systematic account of the regional and laminar distribution of catecholamine-mediated innervation of the human cerebral cortex.
28. Lewis, D. A. The catecholaminergic innervation of primate prefrontal cortex. J. Neural Transm. 36, 179-200 (1992).
29. Berger, B., Trottier, S., Verney, C., Gaspar, P. & Alvarez, C. Regional and laminar distribution of the dopamine and serotonin innervation in the macaque cerebral cortex: a radioautographic study. J. Comp. Neurol. 273, 99-119 (1988).
30. Lewis, D. A., Foote, S. L. & Cha, C. I. Corticotropin-releasing factor immunoreactivity in monkey neocortex: an immunohistochemical analysis. J. Comp. Neurol. 290, 599-613 (1989).
31. Campbell, M. J., Lewis, D. A., Benoit, R. & Morrison, J. H. Regional heterogeneity in the distribution of somatostatin-28-and somatostatin-28(1-12)-immunoreactive profiles in monkey neocortex. J. Neurosci. 7, 1133-1144 (1987).
32. Gaspar, P., Berger, B. & Febvret, A. Neurotensin innervation of the human cerebral cortex: lack of colocalization with catecholamines. Brain Res. 530, 181-195 (1990).
33. Satoh, K. & Matsumura, H. Distribution of neurctensin-containing fibers in the frontal cortex of the macaque monkey. J. Comp. Neurol. 298, 215-223 (1990).
34. Iritani, S., Fujii, M. & Satoh K. The distribution of substance P in the cerebral cortex and hippocampal formation: an immunohistochemical study in the monkey and rat. Brain Res. Bull. 22, 295-303 (1989).
35. Showers, M. J. C. The cingulate gyrus: additional motor area and cortical autonomic regulator. J. Comp. Neurol. 112, 231-287 (1959).
36. Hughes, J. R. & Mazurowski, J. A. Studies of the supracallosal mesial cortex of unanaesthetized, conscious mammals. II. Monkey. A. Movements elicited by electrical stimulation. Electroenphalogr. Clin. Neurophysiol. 14, 477-485 (1962).
37. Penfield, W. & Welch, K. The supplementary motor area of the cerebral cortex. A clinical and experimental study. Arch. Neurol. Psychiatry (Lond.) 66, 289-317 (1951).
38. Talairach, J. & Bancaud, J. The supplementary motor area in man. Int. J. Neurol. 5, 330-347 (1966).
39. Luppino, G., Matelli, M., Camarda, R. M., Gallese, V. & Rizzolatti, G. Multiple representations of body movements in mesial area 6 and the adjacent cingulate cortex: an intracortical microstimulation study in the macaque monkey. J. Comp. Neurol. 311, 463-482 (1991). The first microstimulation study of cingulate motor areas in the macaque monkey.
40. Shima, K. et al. Two movement-related foci in the primate cingulate cortex observed in signal-triggered and self-paced forelimb movements. J. Neurophysiol. 65, 188-202 (1991). The first demonstration of functional specialization of the rostral and caudal cingulate motor areas in the monkey.
41. Shima, K. & Tanji, J. Role for cingulate motor area cells in voluntary movement selection based on reward. Science 282, 1335-1338 (1998).
42. Procyk, E., Tanaka, Y. L. & Joseph, J. P. Anterior cingulate activity during routine and non-routine sequential behaviors in macaques. Nature Neurosci. 3, 502-508 (2000).
43. Wu, C. W., Bichot, N. P. & Kaas, J. H. Converging evidence from microstimulation, architecture, and connections for multiple motor areas in the frontal and cingulate cortex of prosimian primates. J. Comp. Neurol. 423, 140-177 (2000). A striking demonstration of similarities in the organization of cortical motor areas between prosimians and monkeys.
44. Kaada, B. in Neurophysiology Vol. II (eds Field, J., Magoun, H. & Hall, V.) 1345-1372 (American Physiological Society, Washington DC, 1960).
45. Jürgens, U. & Plog, D. Cerebral representation of vocalication in the squirrel monkey. Exp. Brain Res. 10, 532-554 (1970).
46. Müller-Preuss, P., Newman, J. D. & Jürgens, U. Anatomical and physiological evidence for a relationship between the 'cingular' vocalization area and the auditory cortex in the squirrel monkey. Brain Res. 202, 307-315 (1980).
47. Gooler, D. M. & O'Neill, W. E. Topographic representation of vocal frequency demonstrated by microstimulation of anterior cingulate cortex in the echolocating bat, Pteronotus pamelli pamelli. J. Comp. Physiol. A 161, 283-294 (1987).
48. Paus, T., Petrides, M., Evans, A. C. & Meyer, E. Role of the human anterior cingulate cortex in the control of oculomotor, manual, and speech responses: a positron emission tomography study. J. Neurophysiol. 70, 453-469 (1993).
49. Talairach, J. & Toumoux, P. Co-planar Stereotaxic Atlas of the Human Brain (Thieme Medical, New York, 1988).
50. Paus, T., Koski, L., Caramanos, Z. & Westbury, C. Regional differences in the effects of task difficulty and motor output on blood flow response in the human anterior cingulate cortex: a review of 107 PET activation studies. Neuroreport 9, R37-47 (1998).
51. Pardo, J. V., Pardo, P. J., Janer, K. W. & Raichle, M. E. The anterior cingulate cortex mediates processing selection in the Stroop attentional conflict paradigm. Proc. Natl Acad. Sci. USA 87, 256-259 (1990).
52. Corbetta, M., Miezin, F. M., Dobmeyer, S., Shulman, G. L. & Petersen, S. E. Selective and divided attention during visual discriminations of shape, color, and speed: functional anatomy by positron emission tomography. J. Neurosci. 11, 2383-2402 (1991).
53. Frith, C. D. Friston, K., Liddle, P. F. & Frackowiak, R. S. Willed action and the prefrontal cortex in man: a study with PET. Proc. R. Soc. Lond. B 244, 241-246 (1991).
54. Koski, L. & Paus, T. Functional connectivity of the anterior cingulate cortex within the human frontal lobe: a brain-mapping meta-analysis. Exp. Brain Res. 133, 55-65 (2000).
55. Simpson, J. R., Snyder, A. Z., Gusnard, D. A. & Raichle, M. E. Emotion-induced changes in human medial prefrontal cortex. I. During cognitive task performance. Proc. Natl Acad. Sci. USA 98, 683-687 (2001).
56. Simpson, J. R. Drevets, W. C., Snyder, A. Z., Gusnard, D. A. & Raichle, M. E. Emotion-induced changes in human medial prefrontal cortex. II. During anticipatory anxiety. Proc. Natl Acad. Sci. USA 98, 688-693 (2001).
57. Paus, T., Castro-Alamancos, M. & Petrides, M. Cortico-cortical connectivity of the human mid-dorsolateral frontal cortex and its modulation by repetitive transcranial magnetic stimulation: a combined TMS/PET study. Neuroimage 11, S765 (2000).
58. Falkenstein, M., Hohnsbein, J., Hoorman, J. & Blanke, L. Effects of crossmodal divided attention on late ERP components. II. Error processing in choice reaction tasks. Electroencephalogr. Clin. Neurophysiol. 78, 447-455 (1991).
59. Gehring, W. J., Goss, B., Coles, M. G. H., Meyer, D. E. & Donchin, E. A neural system for error detection and compensation. Psychol. Sci. 4, 385-390 (1993).
60. Deheane, S., Posner, M. I. & Tucker, D. M. Localization of a neural system for error detection and compensation. Psychol. Sci. 5, 303-305 (1994).
61. Vidal, F., Hasbroucq, T., Grapperon, J. & Bonnet, M. Is the 'error negativity' specific to errors? Biol. Psychol. 51, 109-128 (2000).
62. Tucker, D. M., Hartry-Speiser, A., McDougal, L., Luu, P. & deGrandpre, D. Mood and spatial memory: emotion and right hemisphere contribution to spatal cognition. Biol. Psychol. 50, 103-125 (1999).
63. Luu, P., Collins, P. & Tucker, D. M. Mood, personality, and self-monitoring: negative affect and emotionality in relation to frontal lobe mechanisms of error monitoring. J. Exp. Psychol. Gen. 129, 43-60 (2000).
64. Gehring, W. J. & Knight, R. T. Prefrontal-cingulate interactions in action monitoring. Nature Neurosci. 3, 516-520 (2000). A critical demonstration of the contribution of the lateral prefrontal cortex in the generation of error-related negativity.
65. Aston-Jones, G., Rajkowski, J. & Cohen, J. Locus coeruleus and regulation of behavioural flexibility and attention. Prog. Brain Res. 126, 165-182 (2000).
66. Swick, D., Pineda, J. A., Schacher, S. & Foote, S. L. Locus coeruleus neuronal activity in awake monkeys: relationship to auditory P300-like potentials and spontaneous EEG. Exp. Brain Res. 101, 86-92 (1994).
67. Carter, C. S., Botvinick, M. M. & Cohen, J. D. The contribution of the anterior cingulate cortex to executive processes in cognition. Rev. Neurosci. 10, 49-57 (1999).
68. Carter, C. S. et al. Anterior cingulate cortex, error detection, and the online monitoring of performance. Science 280, 747-749 (1998).
69. Carter, C. S. et al. Parsing executive processes: strategic vs. evaluative functions of the anterior cingulate cortex. Proc. Natl Acad. Sci. USA 97, 1944-1948 (2000).
70. Milham, M. et al. Activity of cingulate-based attentional system in the Stroop task is dependent upon response eligibility, a hybrid blocked/event-related fMRI design. Neuroimage 6, S751 (1999).
71. MacDonald, A. W., Cohen, J. D., Stenger, V. A. & Carter, C. S. Dissociating the role of the dorsolateral prefrontal and anterior cingulate cortex in cognitive control. Science 288, 1835-1838 (2000). An fMRI study of task preparation and execution, which provides the first functional evidence for differential engagement of the lateral prefrontal cortex and the anterior cingulate cortex during the performance of the Stroop task.
72. Banich, M. T. et al. Prefrontal regions play a predominant role in imposing an attentional 'set': evidence from fMRI. Brain Res. Cogn. Brain Res. 10, 1-9 (2000).
73. Paus, T. et al. Time-related changes in neural systems underlying attention and arousal during the performance of an auditory vigilance task. J. Cogn. Neurosci. 9, 392-408 (1997).
74. Hofle, N. et al. Regional cerebral blood flow changes as a function of delta and spindle wave activity during slow wave sleep in humans. J. Neurosci. 17, 4800-4808 (1997).
75. Fiset, P. et al. Brain mechanisms of propofol-induced loss of consciousness in humans: a PET study. J. Neurosci. 19, 5506-5513 (1999).
76. Paus, T. Functional anatomy of arousal and attention systems in the human brain. Prog. Brain Res. 126, 65-77 (2000).
77. Thierry, A.-M., Godbout, R., Mantz, J. & Glowinski, J. Influence of the ascending monoaminergic systems on the activity of the rat prefrontal cortex. Prog. Brain Res. 85, 355-363 (1990).
78. Deutch, A. Y. & Roth, R. H. The determinants of stress-induced activation of the prefrontal cortical dopamine system. Prog. Brain Res. 85, 365-401 (1990). An excellent and still timely review of neurotransmitters and neuromodulators involved in the cortical response to stress.
79. Bertolucci-D'Angio, M., Serrano, A., Driscoll, P. & Scatton, B. Involvement of mesocorticolimbic dopaminergic systems in emotional states. Prog. Brain Res. 85, 405-417 (1990).
80. Grasby, P. M. et al. The effect of the dopamine agonist, apomorphine, on regional cerebral blood flow in normal volunteers. Psychol. Med. 23, 605-612 (1993).
81. 2O PET study in humans. Neurosci. Lett. 176, 21-24 (1994).
82. Bartlett, E. J. et al. Effects of haloperidol challenge on regional cerebral glucose utilization in normal human subjects. Am. J. Psychiatry 151, 681-686 (1994).
83. Paus, T. et al. Alpha-methyl-para-tyrosine (AMPT) attenuate: task-specific CBF changes in the human anterior cingulate cortex. Soc. Neurosci.-Abstr. 20, 353 (1994).
84. Bams, R. W. & Schuman, H. R. Bilateral anterior cingulate gyrus lesions. Syndrome of the anterior cingulate gyri. Neurology 3, 44-52 (1953).
85. Laplane, D., Degos, J. D., Maulac, M. & Gray, F. Bilateral infarctions of the anterior cingulate gyri and of the fornices. J. Neurol. Sci. 51, 289-300 (1981).
86. Nielsen, J. M. & Jacobs, L. L. Bilateral lesions of the anterior cingulate gyri. Report of case. Bull. Los Angeles Neurol. Soc. 16, 231-234 (1951).
87. Buge, A., Escourolle, R., Rancurel, G. & Poisson, M. Mutisme akinétique et ramollissement bicingulaire. 3 observations anatomo-cliniques. Rev. Neurol. (Paris) 131, 121-137 (1975).
88. Németh, G., Hegedüs, K. & Molnár, L. Akinetic mutism associated with bicingular lesions: clinicopathological and functional anatomical correlates. Eur. Arch. Psychiatry Neurol. Sci. 237, 218-222 (1988).
89. Laplane, D., Talairach, J., Meininger, V., Bancaud, J. & Orgogozo, J. M. Clinical consequences of corticectomies involving the supplementary motor area in man. J. Neurol. Sci. 34, 301-314 (1977).
90. Jürgens, U. & Von Cramon, D. On the role of the anterior cingulate cortex in phonation: a case report. Brain Lang. 15, 234-248 (1982).
91. Shahani, B., Burrows, P. & Whitty, C. W. M. The grasp reflex and perseveration. Brain 93, 181-192 (1970).
92. De Renzi, E. & Babieri, C. The incidence of the grasp reflex following hemispheric lesion and its relation to frontal damage. Brain 115, 293-313 (1992).
93. Hashimoto, R. & Tanaka, Y. Contribution of the supplementary motor area and anterior cingulate gyrus to pathological grasping phenomena. Eur. Neurol. 40, 151-158 (1998).
94. Banks, G. et al. The alien hand syndrome. Clinical and postmortem findings. Arch. Neurol. 46, 456-459 (1989).
95. Goldberg, G., Mayer, N. H. & Toglia, J. U. Medial frontal cortex infarction and the alien hand sign. Arch. Neurol. 38, 683-686 (1981).
96. Gaymard, B. et al. Effects of anterior cingulate cortex lesions on ocular saccades in humans. Exp. Brain Res. 120, 173-183 (1998).
97. Paus, T. et al. Medial vs. lateral frontal lobe lesions and differential impairment of central gaze fixation maintenance in man. Brain 114, 2051-2067 (1991).
98. Stephan, K. M. et al. The role of ventral medial wall motor areas in bimanual co-ordination. A combined lesion and activation study. Brain 122, 351-368 (1999).
99. Turken, A. U. & Swick, D. Response selection in the human anterior cingulate cortex. Nature Neurosci. 2, 920-924 (1999). An important demonstration of cognitive impairment circumscribed to a single response modality.
100. Sutton, D., Larson, C. & Undeman, R. C. Neocortical and limbic lesion effects on primate phonation. Brain Res. 71, 61-75 (1974).
101. Sutton, D., Trachy, R. E. & Undeman, R. C. Primate phonation: unilateral and bilateral cingulate lesion effects. Behav. Brain Res. 3, 99-114 (1981).
102. Aitken, P. G. Cortical control of conditioned and spontaneous vocal behavior in rhesus monkeys. Brain Lang. 13, 171-184 (1981). An analysis of self-initiated vocalization in monkeys with lesions to the anterior cingulate cortex and to the areas homologous to Broca's and Wemicke's on the convexity of the frontal lobes.
103. MacLean, P. D. & Newman, J. D. Role of midline frontolimbic cortex in production of the isolation call of squirrel monkeys. Brain Res. 450, 111-123 (1988).
104. Pribram, K. H., Wilson, W. A. Jr & Connors, J. Effects of lesions of the medial forebrain on alteration behavior of rhesus monkeys. Exp. Neurol. 6, 36-47 (1962).
105. Gabriel, M. Functions of anterior and posterior cingulate cortex during avoidance learning in rabbits. Prog. Brain Res. 85, 465-481 (1990).
106. Raichle, M. E. et al. Practice-related changes in human brain functional anatomy during nonmotor learning. Cereb. Cortex 4, 8-26 (1994).
107. Glowinski, J. in Monoamine Innervation of Cerebral Cortex (eds Descarries, L., Reader, T. R. & Jasper, H. H.) 229-231 (Alan R. Liss, New York, 1984).
108. Ross, E. D. & Stewart, R. M. Akinetic mutism from hypothalamic damage: successful treatment with dopamine agonists. Neurology 31, 1435-1439 (1981). A case study of the putative loss of dopamine-mediated modulation of the anterior cingulate cortex owing to a lesion of the anterior hypothalamus that also involved the medial forebrain bundle.
109. Sarkissov, S., Flimonoff, J., Kononova, E., Preobraschenskaja, I. & Kukuew, L. Atlas of the Cytoarchitectonics of the Human Cerebral Cortex (Medzig, Moscow, 1955).
110. Vogt, B. A., Nimchinsky, E. A., Vogt. L. J. & Hof, P. R. Human cingulate cortex: surface features, flat maps, and cytoarchitecture. J. Comp. Neurol. 359, 490-506 (1995). Systematic study of the cingulate cytoarchitecture and its relationship to the sulcal pattern in the human brain.