Selective inhibition of interleukin-8-induced neutrophil chemotaxis by ketoprofen isomers

Biochemical Pharmacology

Volumn 61, Issue 11, 2001, Pages 1429-1437

  Bizzarri, Cinzia ^a   Pagliei, Sabrina ^b   Brandolini, Laura ^b   Mascagni, Patrizia ^b   Caselli, Gianfranco ^b   Transidico, Pietro ^c   Sozzani, Silvano ^c   Bertini, Riccardo ^b  

^a Consorzio Biolaq ^*  (Italy)

^b Chemistry Section   (Italy)

^c MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

Chemotaxis; Interleukin 8; Intracellular mediators; Isomers; Ketoprofen; Neutrophils

Indexed keywords

CALCIUM ION; GLYCOPROTEIN P; INTERLEUKIN 8; ISOENZYME; KETOPROFEN; MITOGEN ACTIVATED PROTEIN KINASE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE; PROTEIN INHIBITOR;

ARTICLE; CALCIUM CELL LEVEL; CELL ACTIVITY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; ISOMER; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; STEREOCHEMISTRY;

CALCIUM; CHEMOKINE CCL2; CHEMOTAXIS; COMPLEMENT C5A; CYCLOOXYGENASE INHIBITORS; DRUG INTERACTIONS; ENZYME ACTIVATION; HUMANS; INTERLEUKIN-8; KETOPROFEN; LEUKOCYTES; MITOGEN-ACTIVATED PROTEIN KINASES; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; STEREOISOMERISM;

EID: 0035371366     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00610-4     Document Type: Article

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