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Volumn 113, Issue 1-3, 1996, Pages 31-39

Effects of the structure of a toxicokinetic model of butadiene inhalation exposure on computed production of carcinogenic intermediates

Author keywords

1,3 butadiene; parameter sensitivity; toxicokinetic modeling

Indexed keywords

1,3 BUTADIENE; CARCINOGEN; EPOXIDE HYDROLASE; GLUTATHIONE; GLUTATHIONE TRANSFERASE;

EID: 0030605127     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0300-483X(96)03424-5     Document Type: Conference Paper
Times cited : (17)

References (36)
  • 2
    • 0021221991 scopus 로고
    • Inhalation pharmacokinetics based on gas uptake studies. V. Comparitive pharmacokinetics of ethylene and 1,3-butadiene in rats
    • Bolt, H.M., Filser, J.G. and Stormer, F. (1984) Inhalation pharmacokinetics based on gas uptake studies. V. Comparitive pharmacokinetics of ethylene and 1,3-butadiene in rats. Arch. Toxicol. 55, 213-218.
    • (1984) Arch. Toxicol. , vol.55 , pp. 213-218
    • Bolt, H.M.1    Filser, J.G.2    Stormer, F.3
  • 4
    • 0028332680 scopus 로고
    • Modifications of glutathione S-transferase (GST) activity in the last period of pregnancy in rats treated with benzo[a]pyrene (BP)
    • Cervello, I., Giralt, M., Nogues, M.R., Ortin, F., Puerto, A.M. and Mallol, J. (1994) Modifications of glutathione S-transferase (GST) activity in the last period of pregnancy in rats treated with benzo[a]pyrene (BP). Placenta 15, 431-440.
    • (1994) Placenta , vol.15 , pp. 431-440
    • Cervello, I.1    Giralt, M.2    Nogues, M.R.3    Ortin, F.4    Puerto, A.M.5    Mallol, J.6
  • 5
  • 6
    • 0026741034 scopus 로고
    • Comparison of the biotransformation of 1,3-butadiene and its metabolite, butadiene monoepoxide, by hepatic and pulmonary tissues from humans, rats, and mice
    • Csanady, G.A., Guengerich, F.P. and Bond, J.A. (1992) Comparison of the biotransformation of 1,3-butadiene and its metabolite, butadiene monoepoxide, by hepatic and pulmonary tissues from humans, rats, and mice. Carcinogenesis 13, 1143-1153.
    • (1992) Carcinogenesis , vol.13 , pp. 1143-1153
    • Csanady, G.A.1    Guengerich, F.P.2    Bond, J.A.3
  • 7
    • 0027275566 scopus 로고
    • Physiological parameters in laboratory animals and humans
    • Davies, B. and Morris, T (1993) Physiological parameters in laboratory animals and humans. Pharm. Res. 10, 1093-1095.
    • (1993) Pharm. Res. , vol.10 , pp. 1093-1095
    • Davies, B.1    Morris, T.2
  • 8
    • 0026322252 scopus 로고
    • Distribution of cardiac output during diurnal changes of activity in rats
    • Delp, M.D, Manning, R.O., Bruckner, J.V. and Armstrong, R.B. (1991) Distribution of cardiac output during diurnal changes of activity in rats. Am. J. Physiol. 261, H1487-H1493.
    • (1991) Am. J. Physiol. , vol.261
    • Delp, M.D.1    Manning, R.O.2    Bruckner, J.V.3    Armstrong, R.B.4
  • 9
    • 0019125048 scopus 로고
    • The mutagenicity of butadiene towards Salmonella typhimurium
    • de Meester, P.F., Roberfroid, M. and Mercier, M. (1980) The mutagenicity of butadiene towards Salmonella typhimurium. Toxicol. Lett. 6, 125-130.
    • (1980) Toxicol. Lett. , vol.6 , pp. 125-130
    • De Meester, P.F.1    Roberfroid, M.2    Mercier, M.3
  • 10
    • 0025344378 scopus 로고
    • Cytochrome P450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues
    • de Waziers, I., Cugnenc, P.H., Yang, C.S., Leroux, J.-P. and Beaune, P.H. (1990) Cytochrome P450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues. Pharmacol. Exp. Ther. 253, 387-394.
    • (1990) Pharmacol. Exp. Ther. , vol.253 , pp. 387-394
    • De Waziers, I.1    Cugnenc, P.H.2    Yang, C.S.3    Leroux, J.-P.4    Beaune, P.H.5
  • 11
    • 0024500970 scopus 로고
    • Concentration-dependent depletion of non-protein sulfhydryl (NPSH) content in lung, heart and liver tissue of rats and mice after cute inhalation exposure to butadiene
    • Deutschmann, S. and Laib, R.J. (1989) Concentration-dependent depletion of non-protein sulfhydryl (NPSH) content in lung, heart and liver tissue of rats and mice after cute inhalation exposure to butadiene. Toxicol. Lett. 45, 175-183.
    • (1989) Toxicol. Lett. , vol.45 , pp. 175-183
    • Deutschmann, S.1    Laib, R.J.2
  • 12
    • 0027424629 scopus 로고
    • Physiologically based pharmacokinetic modeling of 1,3-butadiene lung metabolism in mice becomes more important at low doses
    • Evelo, C.T.A., Ostendorp, J.G.M., ten Berge, W.F. and Borm, P.J.A. (1993) Physiologically based pharmacokinetic modeling of 1,3-butadiene lung metabolism in mice becomes more important at low doses. Environ. Health Perspect. 101, 496-502.
    • (1993) Environ. Health Perspect. , vol.101 , pp. 496-502
    • Evelo, C.T.A.1    Ostendorp, J.G.M.2    Ten Berge, W.F.A.3    Borm, P.J.A.4
  • 13
    • 0021162019 scopus 로고
    • Inhalation pharmacokinetics based on gas uptake studies. VI. Comparitive evaluation of ethylene and butadiene monoxide as exhaled reactive metabolites of ethylene and 1,3-butadiene in rats
    • Filser, J.G. and Bolt, H.M. (1984) Inhalation pharmacokinetics based on gas uptake studies. VI. Comparitive evaluation of ethylene and butadiene monoxide as exhaled reactive metabolites of ethylene and 1,3-butadiene in rats. Arch. Toxicol. 55, 219-223.
    • (1984) Arch. Toxicol. , vol.55 , pp. 219-223
    • Filser, J.G.1    Bolt, H.M.2
  • 14
    • 0028092965 scopus 로고
    • Comparison of blood concentration of 1,3-butadiene and butadiene epoxides in mice an rats exposed to 1,3-butadiene by inhalation
    • Himmelstein, M.W., Turner, M.J., Asgharian, B. and Bond, J.A. (1994) Comparison of blood concentration of 1,3-butadiene and butadiene epoxides in mice an rats exposed to 1,3-butadiene by inhalation. Carcinogenesis 15, 1479-1486.
    • (1994) Carcinogenesis , vol.15 , pp. 1479-1486
    • Himmelstein, M.W.1    Turner, M.J.2    Asgharian, B.3    Bond, J.A.4
  • 15
    • 0021916824 scopus 로고
    • Multiple organ carcinogenicity of 1,3-butadiene in B6C3F1 mice after 60 weeks of inhalation exposure
    • Huff, J.E., Melnick, R.L., Solleveld, H.A., Haseman, J.K., Powers, M. and Miller, R.A. (1985) Multiple organ carcinogenicity of 1,3-butadiene in B6C3F1 mice after 60 weeks of inhalation exposure. Science 227, 548-549.
    • (1985) Science , vol.227 , pp. 548-549
    • Huff, J.E.1    Melnick, R.L.2    Solleveld, H.A.3    Haseman, J.K.4    Powers, M.5    Miller, R.A.6
  • 16
    • 0027536879 scopus 로고
    • A physiologically based pharmacokinetic model for butadiene and its metabolite butadiene monoxide in rat and mouse and its significance for risk extrapolation
    • Johanson, G. and Filser, J.G. (1993) A physiologically based pharmacokinetic model for butadiene and its metabolite butadiene monoxide in rat and mouse and its significance for risk extrapolation. Arch. Toxicol. 67, 131-163.
    • (1993) Arch. Toxicol. , vol.67 , pp. 131-163
    • Johanson, G.1    Filser, J.G.2
  • 17
    • 0027324706 scopus 로고
    • Species differences in the production and clearance of 1,3-butadiene metabolites: A mechanistic model indicates predominantly physiological, not biochemical, control
    • Kohn, M.C. and Melnick, R.L. (1993) Species differences in the production and clearance of 1,3-butadiene metabolites: a mechanistic model indicates predominantly physiological, not biochemical, control. Carcinogenesis 14, 619-628.
    • (1993) Carcinogenesis , vol.14 , pp. 619-628
    • Kohn, M.C.1    Melnick, R.L.2
  • 20
    • 0022534543 scopus 로고
    • Species differences in butadiene metabolism between mice and rats evaluated by inhalation pharmacokinetics
    • Kreiling, R., Laib, R.J. and Bolt, H.M (1986) Species differences in butadiene metabolism between mice and rats evaluated by inhalation pharmacokinetics. Arch. Toxicol. 58, 235-238.
    • (1986) Arch. Toxicol. , vol.58 , pp. 235-238
    • Kreiling, R.1    Laib, R.J.2    Bolt, H.M.3
  • 21
    • 0023231059 scopus 로고
    • Inhalation pharmacokinetics of 1,2-epoxybutene-3 reveal species differences between rats and mice sensitive to butadiene-induced carcinogenesis
    • Kreiling, R., Laib, R.J., Filser, J.G. and Bolt, H.M. (1987) Inhalation pharmacokinetics of 1,2-epoxybutene-3 reveal species differences between rats and mice sensitive to butadiene-induced carcinogenesis. Arch. Toxicol. 61, 7-11.
    • (1987) Arch. Toxicol. , vol.61 , pp. 7-11
    • Kreiling, R.1    Laib, R.J.2    Filser, J.G.3    Bolt, H.M.4
  • 22
  • 23
    • 0020078715 scopus 로고
    • Hepatic microsomal metabolism of 1,3-butadiene
    • Malvoisin, E. and Roberfroid, M. (1982) Hepatic microsomal metabolism of 1,3-butadiene. Xenobiotica 12, 137-144.
    • (1982) Xenobiotica , vol.12 , pp. 137-144
    • Malvoisin, E.1    Roberfroid, M.2
  • 24
    • 0025024864 scopus 로고
    • Mortality of a cohort of workers in the styrene-butadiene polymer manufacturing industry (1943-1982)
    • Matanoski, G.M., Santos-Burgoa, C. and Schwartz, L. (1990) Mortality of a cohort of workers in the styrene-butadiene polymer manufacturing industry (1943-1982). Environ. Health Perspect. 86, 107-117.
    • (1990) Environ. Health Perspect. , vol.86 , pp. 107-117
    • Matanoski, G.M.1    Santos-Burgoa, C.2    Schwartz, L.3
  • 25
    • 0028362118 scopus 로고
    • In vivo metabolism of butadiene by mice and rats: A comparison of physiological model predictions and experimental data
    • Medinsky, M.A., Leavens, T.L., Csanady, G.A., Gargas, M.L. and Bond, J.A. (1994) In vivo metabolism of butadiene by mice and rats: a comparison of physiological model predictions and experimental data. Carcinogenesis 15, 1329-1340.
    • (1994) Carcinogenesis , vol.15 , pp. 1329-1340
    • Medinsky, M.A.1    Leavens, T.L.2    Csanady, G.A.3    Gargas, M.L.4    Bond, J.A.5
  • 26
    • 0025048644 scopus 로고
    • Carcinogenicity of 1,3-butadiene in C57BL/6 × C3H F1 mice at low exposure concentrations
    • Melnick, R.L., Huff, J., Chou, B.J. and Miller R. (1990) Carcinogenicity of 1,3-butadiene in C57BL/6 × C3H F1 mice at low exposure concentrations. Cancer Res. 50, 6592-6599.
    • (1990) Cancer Res. , vol.50 , pp. 6592-6599
    • Melnick, R.L.1    Huff, J.2    Chou, B.J.3    Miller, R.4
  • 27
    • 0023262639 scopus 로고
    • Inhalation toxicity studies with 1,3-butadiene. 3. Two-year toxicity/carcinogenicity studies in rats
    • Owen, P.E., Glaister, J.R., Gaunt, I.F. and Pullinger, D.H. (1987) Inhalation toxicity studies with 1,3-butadiene. 3. Two-year toxicity/carcinogenicity studies in rats. Am. Ind. Hyg. Assoc. J. 48, 407-413.
    • (1987) Am. Ind. Hyg. Assoc. J. , vol.48 , pp. 407-413
    • Owen, P.E.1    Glaister, J.R.2    Gaunt, I.F.3    Pullinger, D.H.4
  • 28
    • 0027507612 scopus 로고
    • A physiologically based model for gastrointestinal absorption and excretion of chemicals carried by lipids
    • Roth, W.L., Freeman, R.A. and Wilson, A.G.E. (1993) A physiologically based model for gastrointestinal absorption and excretion of chemicals carried by lipids. Risk Anal. 13, 531-543.
    • (1993) Risk Anal. , vol.13 , pp. 531-543
    • Roth, W.L.1    Freeman, R.A.2    Wilson, A.G.E.3
  • 29
    • 0026778582 scopus 로고
    • Species differences in urinary butadiene metabolites; identification of 1,2-dihydroxy-4-(N-acetylcysteinyl)butane, a novel metabolite of butadiene
    • Sabourin, P.J., Burka, L.T., Bechtold, W.E., Dahl, A.R., Hoover, M.D., Chang, I.Y. and Henderson, R.F. (1992) Species differences in urinary butadiene metabolites; identification of 1,2-dihydroxy-4-(N-acetylcysteinyl)butane, a novel metabolite of butadiene. Carcinogenesis 13, 1633-1638.
    • (1992) Carcinogenesis , vol.13 , pp. 1633-1638
    • Sabourin, P.J.1    Burka, L.T.2    Bechtold, W.E.3    Dahl, A.R.4    Hoover, M.D.5    Chang, I.Y.6    Henderson, R.F.7
  • 30
    • 0026540253 scopus 로고
    • Lymphohematopoietic cancer in styrene-butadiene polymerization workers
    • Santos-Burgoa, C., Matanoski, G.M., Zeger, S.L. and Schwartz, L. (1992) Lymphohematopoietic cancer in styrene-butadiene polymerization workers. Am. J. Epidemiol. 136, 843-854.
    • (1992) Am. J. Epidemiol. , vol.136 , pp. 843-854
    • Santos-Burgoa, C.1    Matanoski, G.M.2    Zeger, S.L.3    Schwartz, L.4
  • 31
    • 0026669438 scopus 로고
    • Species and tissue differences in the microsomal oxidation of 1,3-butadiene and the glutathione conjugation of butadiene monoxide in mice and rats. Possible role in 1,3-butadiene-induced toxicity
    • Sharer, J.E., Duescher, R.J. and Elfarra, A.A. (1992) Species and tissue differences in the microsomal oxidation of 1,3-butadiene and the glutathione conjugation of butadiene monoxide in mice and rats. Possible role in 1,3-butadiene-induced toxicity. Drug Metab. Dispos. 20, 658-664.
    • (1992) Drug Metab. Dispos. , vol.20 , pp. 658-664
    • Sharer, J.E.1    Duescher, R.J.2    Elfarra, A.A.3
  • 32
    • 0018856815 scopus 로고
    • Distribution and excretion of 2,2′,4,4′,5,5′-hexabromobiphenyl in rats and man: Pharmacokinetic model predictions
    • Tuey, D.B. and Matthews, H.B. (1980) Distribution and excretion of 2,2′,4,4′,5,5′-hexabromobiphenyl in rats and man: pharmacokinetic model predictions. Toxicol. Appl. Pharmacol. 53, 420-431.
    • (1980) Toxicol. Appl. Pharmacol. , vol.53 , pp. 420-431
    • Tuey, D.B.1    Matthews, H.B.2
  • 33
    • 9844240951 scopus 로고
    • United States International Trade Commission, Publ. 2338, U.S. Government Printing Office, Washington, DC
    • USITC (1990) Synthetic organic chemicals; United States production and sales, 1989. United States International Trade Commission, Publ. 2338, U.S. Government Printing Office, Washington, DC.
    • (1990) Synthetic Organic Chemicals; United States Production and Sales, 1989
  • 35
    • 0018411986 scopus 로고
    • Mutagenic action of a series of epoxides
    • Wade, M.J., Moyer, J.W. and Hine, C.H. (1979) Mutagenic action of a series of epoxides. Mutat. Res. 66, 367-371.
    • (1979) Mutat. Res. , vol.66 , pp. 367-371
    • Wade, M.J.1    Moyer, J.W.2    Hine, C.H.3
  • 36
    • 0025740043 scopus 로고
    • The effects of bucillamine on glutathione and glutathione-related enzymes in the mouse
    • Yeung, J.H. (1991) The effects of bucillamine on glutathione and glutathione-related enzymes in the mouse. Biochem. Pharmacol. 42, 847-852.
    • (1991) Biochem. Pharmacol. , vol.42 , pp. 847-852
    • Yeung, J.H.1


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