The privileged access model of 1,3-butadiene disposition

Environmental Health Perspectives

Volumn 108, Issue SUPPL. 5, 2000, Pages 911-917

  Kohn, Michael C ^a   Melnick, Ronald L ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

1,3 Butadiene; Enzymatic channeling; Metabolic mechanisms; PBPK modeling

Indexed keywords

1,2 EPOXY 3 BUTENE; 1,3 BUTADIENE; CYTOCHROME P450; EPOXIDE; EPOXIDE HYDROLASE; GLUTATHIONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD FLOW VELOCITY; CONTROLLED STUDY; DATA ANALYSIS; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG CONJUGATION; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HYDROLYSIS; DRUG METABOLISM; DRUG OXIDATION; DRUG PROTEIN BINDING; DRUG TRANSPORT; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; GASTROINTESTINAL TRACT; INTRACELLULAR TRANSPORT; KIDNEY PERFUSION; LIVER PERFUSION; LUNG PERFUSION; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE DISTRIBUTION; TRANSPORT KINETICS;

EID: 0033675385     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.2307/3454324     Document Type: Article

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