Quantitative techniques for the comparison of solid supports

Current Opinion in Chemical Biology

Volumn 5, Issue 3, 2001, Pages 264-268

  Gerritz, Samuel W ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MACROGOL; N,N DIMETHYLFORMAMIDE; POLOXAMER; POLYSTYRENE;

ANALYTIC METHOD; CHEMICAL ANALYSIS; CHEMICAL REACTION; CHEMICAL REACTION KINETICS; DIFFUSION; INFRARED SPECTROSCOPY; INTERMETHOD COMPARISON; NUCLEAR MAGNETIC RESONANCE; PURIFICATION; QUANTITATIVE ASSAY; REVIEW; SYNTHESIS;

EID: 0035358549     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1367-5931(00)00201-5     Document Type: Review

References (35)

1. Matrix assisted synthetic transformations: A mosaic of diverse contributions. I. The pattern emerges
2. Matrix assisted synthetic transformations: A mosaic of diverse contributions. II. The pattern is completed
3. Some problems in the physical and chemical characterization of functionalized supports
4. Solid-phase organic synthesis: A critical understanding of the resin
5. Solid-phase peptide synthesis. I. The synthesis of a tetrapeptide
6. A measure of solvent effects on swelling of resin for solid phase organic synthesis
7. High loading cellulose based poly(alkenyl) resins for resin capture applications in halogenation reactions
8. Surfactant mediated cationic and anionic suspension polymerization of PEG-based resins in silicon oil: Beaded SPOCC 1500 and POEPOP 1500
9. The effect of PEG groups on swelling properties of PEG-grafted-polystyrene resins in various solvents
10. New supports for solid-phase organic synthesis: Development of polystyrene resins containing tetrahydrofuran derived cross-linkers
11. Influence of resin structure, tether length, and solvent upon the high-resolution 1H NMR spectra of solid-phase-synthesis resins
12. Physical properties of poly(ethylene glycol) (PEG)-based resins for combinatorial solid phase organic chemistry: A comparison of PEG-cross-linked and PEG-grafted resins
13. Using one- and two-dimensional NMR techniques to characterize reaction products bound to Chiron Synphase Crowns
14. Multistep synthesis of 2,5-diketopiperazines on different solid supports monitored by high resolution magic angle spinning NMR spectroscopy
15. Solvent and reagent accessibility within oligo(ethylene glycol) ether [PEG] cross-linked polystyrene beads
16. Investigating resins for solid phase organic synthesis: The relationship between swelling and microenvironment as probed by EPR and fluorescence spectroscopy
17. Solid-phase synthesis of hydrophobic peptides on 1,6-hexanediol diacrylate crosslinked polystyrene resin: Comparison with Merrifield resin
18. The synthesis of the cyclic antibacterial peptide Kawaguchipeptin B on 11 different DVB cross-linked PS resins
19. Synthesis of acyl carrier protein fragment 65-74 on a flexible cross-linked polystyrene support: Comparison with Merrified resin
20. Optimization in peptide synthetic conditions of 1,4-butanediol dimethacrylate cross-linked polystyrene resin and its efficiency in solid phase peptide synthesis
21. High load' polyethylene glycol-polystyrene (PEG-PS) graft supports for solid phase synthesis
22. Solid-phase synthesis of aryl ethers on high loading dendrimer resin
23. Polymer discs - An alternative support format for solid phase synthesis
24. Efficiences of reductive amination reactions of different solid supports
25. Improving the performance of an acid-labile 4-hydroxymethyl phenoxyacetic acid (HMP) linker on resin and Synphase™ grafted solid supports
26. Alternative base matrices for solid phase quenching reagents
27. Hydantoin formation by cyclo-elimination: Reactivity difference between Merrifield- and Wang-derived resins
28. N2 macrocyclizations
29. How important is the inert matrix of supported enantiomeric catalysts? Reversal of topicity with two polystyrene backbones
30. Polymer-supported (salen)Mn catalysts for asymmetric epoxidation: A comparison between soluble and insoluble matrices
31. Solid-phase synthesis supports are like solvents
32. Effects of polymer supports on the kinetics of solid-phase organic reactions: A comparison of polystyrene and TentaGel-based resins
33. Kinetic comparison of amide formation on various cross-linked polystyrene resins
34. Kinetic comparison of trifluoroacetic acid cleavage reactions of resin-bound carbamates, ureas, secondary amides and sulfonamides from benzyl-, benzhydryl-, and indole-based linkers
35. Probing the reactivity of solid supports via Hammett relationships