Complementation of Listeria seeligeri with the plcA-prfA genes from L. monocytogenes activates transcription of seeligerolysin and leads to bacterial escape from the phagosome of infected mammalian cells

FEMS Microbiology Letters

Volumn 146, Issue 2, 1997, Pages 303-310

  Karunasagar, Iddya ^a   Lampidis, Robert ^a   Goebel, Werner ^a   Kreft, Jürgen ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

intracellular bacteria; Listeria seeligeri; listeriolysin; transcription activator

Indexed keywords

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENETIC COMPLEMENTATION; LISTERIA MONOCYTOGENES; MAMMAL; NONHUMAN; PHAGOSOME; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

EID: 0031037474     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(96)30493-4     Document Type: Article

References (16)

1. Rocourt, J. and Seeliger, H.P.R. (1987) Is hemolysin an in vitro marker of the pathogenic strains of the genus Listeria? Ann. Microbiol. (Paris) 138, 277-279.
2. Gaillard, J.L., Berche, P., Mounier, J., Richard, S. and Sansonetti, P.J. (1987) In vitro model of penetration and intracellular growth of Listeria monocytogenes in the human enterocyte-like cell line Caco-2. Infect. Immun. 55, 2822-2829.
3. Cossart, P., Vincente, M.F., Mengaud, J., Baquero, F., Perez-Diaz, J.C. and Berche, P. (1989) Listeriolysin O is essential for the virulence of Listeria monocytogenes: Direct evidence obtained by gene complementation. Infect. Immun. 57, 3629-3636.
4. Portnoy, D.A., Jacks, P.A. and Hinrichs, D.J. (1988) Role of hemolysin in the intracellular growth of Listeria monocytogenes. J. Exp. Med. 167, 1459-1471.
5. Haas, A., Dumbsky, M. and Kreft, J. (1992) Listeriolysin genes: Complete sequence of ilo from Listeria ivanovii and of lso from Listeria seeligeri. Biochem. Biophys. Acta 1130, 81-84.
6. Portnoy, D.A., Chakraborty, T., Goebel, W. and Cossart, P. (1992) Molecular determinants of Listeria monocytogenes pathogenesis. Infect. Immun. 60, 1263-1267.
7. Leimeister-Wächter, M., Haffner, C., Domann, E., Goebel, W. and Chakraborty, T. (1990) Identification of a gene that positively regulates the expression of listeriolysin, the major virulence factor of Listeria monocytogenes. Proc. Natl. Acad. Sci. USA 87, 8336-8340.
8. Gouin, E., Mengaud, J. and Cossart, P. (1994) The virulence gene cluster of Listeria monocytogenes is also present in Listeria ivanovii, an animal pathogen, and Listeria seeligeri, a non-pathogenic species. Infect. Immun. 62, 3550-3553.
9. Alexander, J.E., Andrew, P.W., Jones, D. and Roberts, I.S. (1990) Development of an optimized system for electroporation of Listeria species. Lett. Appl. Microbiol. 10, 179-181.
10. Rodriguez, L.D., Vazquez-Boland, J.A., Garayabal, J.F.F., Tranchant, E., Gomez-Lucia, E., Ferri, E.F.R. and Fernandez, G.S. (1986) Microplate technique to determine hemolytic activity for routine typing of Listeria strains. J. Clin. Microbiol. 24, 99-103.
11. Bohne, J., Sokolovic, Z. and Goebel, W. (1994) Transcriptional regulation of prfA and PrfA-regulated virulence genes in Listeria monocytogenes. Mol. Microbiol. 11, 1141-1150.
12. Karunasagar, I., Krohne, G. and Goebel, W. (1993) Listeria ivanovii is capable of cell-to-cell spread involving actin polymerization. Infect. Immun. 61, 162-169.
13. Geoffroy, C., Gaillard, J., Alouf, J.E. and Berche, P. (1989) Production of thiol-dependent hemolysins by Listeria monocytogenes and related species. J. Gen. Microbiol. 135, 481-487.
14. Kreft, J., Bohne, J., Gross, R., Kestler, H., Sokolovic, Z. and Goebel, W. (1995) Control of Listeria monocytogenes virulence by the transcriptional regulator PrfA. In: Signal Transduction and Bacterial Virulence (Rappuoli, R., Scarlato, V., Arico, B., Eds.), pp. 129-142. R.G. Landes, Austin, TX.
15. Domann, E., Wehland, J., Niebuhr, K., Haffner, C., Leimeister-Wächter, M. and Chakraborty, T. (1993) Detection of a prfA-independent promoter responsible for listeriolysin expression in mutant Listeria monocytogenes strains lacking the prfA regulator. Infect. Immun. 61, 3073-3075.
16. Bohne, J., Kestler, H., Uebele, C., Sokolovic, Z. and Goebel, W. (1996) Differential regulation of the virulence genes of Listeria monocytogenes by the transcriptional activator PrfA. Mol. Microbiol. 20, 1189-1198.