Autoimmunity in Chagas heart disease

International Journal for Parasitology

Volumn 31, Issue 5-6, 2001, Pages 555-561

  Leon, J S ^a   Engman, D M ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Autoimmunity; Chagas heart disease Myosin; Myocarditis

Indexed keywords

ANTIBODY PRODUCTION; AUTOIMMUNITY; CHAGAS DISEASE; CONFERENCE PAPER; HUMAN; IMMUNOPATHOGENESIS; MYOCARDITIS; NONHUMAN; TRYPANOSOMA CRUZI;

EID: 0035339844     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-7519(01)00163-1     Document Type: Conference Paper

References (24)

1. Autoimmune myocarditis induced by Trypanosoma cruzi
2. Autoimmunity in Chagas disease cardiomyopathy: Biological relevance of a cardiac myosin-specific epitope crossreactive to an immunodominant Trypanosoma cruzi antigen
3. Autoimmunity in Chagas disease: Identification of cardiac myosin-B13 Trypanosoma cruzi protein crossreactive T cell clones in heart lesions of a chronic Chagas cardiomyopathy patient
4. Anti-myosin humoral immune response following cardiac injury
5. Critical self-epitopes are key to the understanding of self-tolerance and autoimmunity
6. De novo autoimmunity to cardiac myosin after heart transplantation and its contribution to the rejection process
7. Trypanosoma cruzi infection enhances polyreactive antibody response in an acute case of human Chagas disease
8. Mapping autoimmunity genes
9. Chagas disease and the autoimmunity hypothesis
10. Antiheart antibody-dependent cytotoxicity in the sera from mice chronically infected with Trypanosoma cruzi
11. Immunologic studies on a murine model of Chagas disease
12. Autoimmunity in heart disease: Mechanisms and genetic susceptibility
13. Characterisation of autoantibodies generated in mice by immunisation with the C-terminal region of Trypanosoma cruzi ribosomal P1 and P2 proteins
14. Autoantibodies specific for the cardiac myosin isoform are found in mice susceptible to coxsackievirus B3-induced myocarditis
15. Coxsackievirus induced myocarditis in mice: Cardiac myosin autoantibodies do not cross-react with the virus
16. Cardiac myosin induces myocarditis in genetically predisposed mice
17. Autoimmunity in Chagas disease: Immunomodulation of autoimmune and T. cruzi-specific immune responses
18. Infection characteristics of an Ecuadorian Trypanosoma cruzi strain with reduced virulence
19. Kinetics of cytokine gene expression in experimental chagasic cardiomyopathy: Tissue parasitism and endogenous IFN-gamma as important determinants of chemokine mRNA expression during infection with Trypanosoma cruzi
20. Chagas disease etiology: Autoimmunity or parasite persistence?
21. Comparison between autoantibodies arising during Trypanosoma cruzi infection in mice and natural autoantibodies
22. Cardiac antigen-specific autoantibody production is associated with cardiomyopathy in Trypanosoma cruzi-infected mice
23. The functional significance of epitope spreading and its regulation by co-stimulatory molecules
24. Proteolysis and class I major histocompatibility complex antigen presentation