Autoimmunity in heart disease: Mechanisms and genetic susceptibility

Molecular Medicine Today

Volumn 2, Issue 8, 1996, Pages 336-342

  Malkiel, Susan ^a   Kuan, Anita P ^a   Diamond, Betty ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

MURINAE;

AUTOANTIBODY; AUTOANTIGEN; CYTOKINE; MYOSIN;

ANIMAL; ARTICLE; AUTOIMMUNE DISEASE; CHEMISTRY; GENETIC PREDISPOSITION; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; MYOCARDITIS; PHYSIOLOGY; T LYMPHOCYTE;

ANIMALS; AUTOANTIBODIES; AUTOANTIGENS; AUTOIMMUNE DISEASES; CYTOKINES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; IMMUNOHISTOCHEMISTRY; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MYOCARDITIS; MYOSINS; T-LYMPHOCYTES;

EID: 0030210387     PISSN: 13574310     EISSN: None     Source Type: Journal    
DOI: 10.1016/1357-4310(96)81799-0     Document Type: Review

References (43)

1. Aretz, H.T. et al. (1987) Myocarditis: a histopathologic definition and classification, Am. J. Cardiovasc. Pathol. 1, 3-14
2. Neumann, D.A. et al. (1990) Circulating heart-reactive antibodies in patients with myocarditis or cardiomyopathy, J. Am. Coll. Cardiol. 16, 839-846
3. Beisel, K.W. and Traystman, M.D. (1990) Autoimmune myocarditis: a murine model, Immunol. Ser. 52, 267-293
4. Brown, C.A. and O'Connell, J.B. (1995) Myocarditis and idiopathic dilated cardiomyopathy, Am. J. Med. 99, 309-314
5. Lauer, B., Padberg, K., Schultheiss, H.P. and Strauer, B.E. (1994) Autoantibodies against human ventricular myosin in sera of patients with acute and chronic myocarditis, J. Am. Coll. Cardiol. 23, 146-153
6. 2+-channel as cardiac autoantigen, Eur. Heart J. 12 (Suppl. D), 99-104
7. Wallukat, G. et al. (1991) Autoantibodies against the β-adrenergic receptor in human myocarditis and dilated cardiomyopathy: β-adrenergic agonism without desensitization, Eur. Heart J. 12 (Suppl. D), 178-181
8. Schultheiss, H.P. (1989) The significance of autoantibodies against the ADP/ATP carrier for the pathogenesis of myocarditis and dilated cardiomyopathy - clinical and experimental data, Springer Semin. Immunopathol. 11, 15-30
9. Drude, L., Wiemers, F. and Maisch, B. (1991) Impaired myocyte function in vitro incubated with sera from patients with myocarditis, Eur. Heart J. 12 (Suppl. D). 36-38
10. Chow, L.H., Ye, Y., Linder, J. and McManus, B.M. (1989) Phenotypic analysis of infiltrating cells in human myocarditis: an immunohistochemical study in paraffinembedded tissue, Arch. Pathol. Lab. Med. 113, 1357-1362
11. Herskowitz, A. et al. (1990) Induction of major histocompatibility complex antigens within the myocardium of patients with active myocarditis: a nonhistologic marker of myocarditis, J. Am. Coll. Cardiol. 15, 624-632
12. Smith, S.C. and Allen, P.M. (1991) Myosin-induced acute myocarditis is a T-cell mediated disease, J. Immunol. 147, 2141-2147
13. Neu, N., Pummerer, C., Rieker, T. and Berger, P. (1993) T cells in cardiac myosin-induced myocarditis, Clin. Immunol. Immunopathol. 68, 107-110
14. Via, C.S. and Handwerger, B.S. (1993) B-cell and T-cell function in systemic lupus erythematosus, Curr. Opin. Rheumatol. 5, 570-574
15. Racke, M.K. et al. (1994) Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease, J. Exp. Med. 180, 1961-1966
16. Lane, J.R. et al. (1993) Role of IL-1 and tumor necrosis factor in Coxsackie virus-induced autoimmune myocarditis, J. Immunol. 151, 1682-1690
17. Huber, S.A., Polgar, J., Schultheiss, P. and Schwimmbeck, P. (1994) Augmentation of pathogenesis of Coxsackievirus B3 infections in mice by exogenous administration of interleukin-1 and interleukin-2, J. Virol. 68, 195-206
18. Smith, S.C. and Allen, P.M. (1992) Neutralization of endogenous tumor necrosis factor ameliorates the severity of myosin-induced myocarditis, Circ. Res. 70, 856-863
19. Lane, J.R. et al. (1992) Interleukin 1 or tumor necrosis factor can promote Coxsackievirus B3-induced myocarditis in resistant B10.A mice, J. Exp. Med. 175, 1123-1129
20. Kulkarni, A.B. et al. (1995) Animal model: transforming growth factor-β1 null mice, an animal model for inflammatory disorders, Am. J. Pathol. 146, 264-275
21. Theofilopoulos, A.N. (1995) The basis of autoimmunity: part I. Mechanisms of aberrant self-recognition, Immunol. Today 16, 90-98
22. Theofilopoulos, A.N. (1995) The basis of autoimmunity: part II. Genetic predisposition, Immunol. Today 16, 150-159
23. Cunningham, M.W. et al. (1989) Human and murine antibodies cross-reactive with streptococcal M protein and myosin recognize the sequence Gln-Lys-Ser-Lys-Gln in M protein, J. Immunol. 143, 2677-2683
24. Dell, A. et al. (1991) Autoimmune determinants of rheumatic carditis: localization of epitopes in human cardiac myosin, Eur. Heart J. 12 (Suppl. D), 158-162
25. L regions of a human anti-streptococcal monoclonal antibody recognizing streptococcal M protein and human cardiac myosin epitopes, J. Immunol. 154, 4203-4212
26. Cunningham, M.W. et al. (1992) Cytotoxic and viral neutralizing antibodies crossreact with streptococcal M protein, enteroviruses, and human cardiac myosin, Proc. Natl. Acad. Sci. U. S. A. 89, 1320-1324
27. Cunha-Neto, E. et al. (1995) Autoimmunity in Chagas disease cardiopathy: biological relevance of a cardiac myosin-specific epitope crossreactive to an immuno-dominant Trypanosoma cruzi antigen, Proc. Natl. Acad. Sci. U. S. A. 92, 3541-3545
28. 1-adrenergic receptor, J. Exp. Med. 182, 59-65
29. Gauntt, C.J. et al. (1995) Molecular mimicry, anti-Coxsackie B3 neutralizing monoclonal antibodies, and myocarditis, J. Immunol. 154, 2983-2995
30. Liao, L. et al. (1995) Antibody-mediated autoimmune myocarditis depends on genetically determined target organ sensitivity, J. Exp. Med. 18, 1123-1131
31. Campbell, R.D. and Milner, C.M. (1993) MHC genes in autoimmunity, Curr. Opin. Immunol. 5, 887-893
32. Jongeneel, C.V., Acha-Orbea, H. and Blankenstein, T. (1990) A polymorphic microsatellite in the tumor necrosis factor α promoter identifies an allele unique to the NZW mouse strain, J. Exp. Med. 171, 2141-2146
33. Pociot, F. et al. (1993) Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-α and TNF-β by human mononuclear cells: a possible link to insulin-dependent diabetes mellitus, Eur. J. Immunol. 23, 224-231
34. Traystman, M.D. et al. (1991) Susceptibility to Coxsackievirus B3-induced chronic myocarditis maps near the murine TCRa and Myhcα loci on chromosome 14, Am. J. Pathol. 138, 721-726
35. Liao, L. et al. (1993) Cardiac α myosin heavy chains differ in their induction of myocarditis, J. Clin. Invest. 92, 2877-2882
36. Leung, P.S.C. et al. (1993) Chromosome localization and RFLP analysis of PDC-E2: the major autoantigen of primary biliary cirrhosis, Autoimmunity 14, 335-340
37. Tienari, P.J. et al. (1992) Genetic susceptibility to multiple sclerosis linked to myelin basic protein gene, Lancet 340, 987-991
38. Quinn-Lacquer, B.K., Kennedy, J.E., Wei, S.J. and Beisel, K.W. (1992) Characterization of the allelic differences in the mouse cardiac α-myosin heavy chain coding sequence, Genomics 13, 176-188
39. Wegmann, K.W., Zhao, W., Griffin, A.C. and Hickey, W.F. (1994) Identification of myocarditogenic peptides derived from cardiac myosin capable of inducing experimental allergic myocarditis in the Lewis rat, J. Immunol. 153, 892-900
40. k on antigen-presenting cells in the heart, J. Exp. Med. 182, 1291-1300
41. Yoshida, H. et al. (1990) Detection of nephritogenic antigen from the Lewis rat renal tubular basement membrane, Kidney Int. 37, 1286-1294
42. Krolick, K.A., Zoda, T.E. and Thompson, P.A. (1994) Examination of characteristics that may distinguish disease-causing from benign AChR-reactive antibodies in experimental autoimmune myasthenia gravis, Adv. Neuroimmunol. 4, 475-493
43. Pummerer, C.L. et al. (1996) Identification of cardiac myosin peptides capable of inducing autoimmune myocarditis in BALB/c mice, J. Clin. Invest. 97, 2057-2062