Human disease: Calcium signaling in polycystic kidney disease

Current Biology

Volumn 11, Issue 9, 2001, Pages

  Somlo, Stefan ^a   Ehrlich, Barbara ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 0035337902     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00193-2     Document Type: Review

References (29)

1. Polycystic kidney disease
2. The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16
3. PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein
4. The molecular basis of focal cyst formation in human autosomal dominant polycystic kidney disease type I
5. Somatic inactivation of Pkd2 results in polycystic kidney disease
6. Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation
7. Cardiac defects and renal failure in mice with targeted mutations in Pkd2
8. PKD1 interacts with PKD2 through a probable coiled-coil domain
9. Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2
10. The sea urchin sperm receptor for egg jelly is a modular protein with extensive homology to the human polycystic kidney disease protein, PKD1
11. A polycystic kidney disease gene homolog required for male mating behavior in Caenorhabiditis elegans
12. Polycystin-L is a calcium-regulated cation channel permeable to calcium ions
13. 2+-permeable nonselective cation channel
14. Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents
15. A latrophilin/CL-1-like GPS domain in polycystin-1
16. The multidomain receptor REJ3 links kidney disease to the sea urchin acrosome reaction
17. Characterization of sea urchin polycystin-2
18. Cloning of the gene encoding a novel integral membrane protein, mucolipidin-and identification of the two major founder mutations causing mucolipidosis type IV
19. Identification and characterization of polycystin-2, the PKD2 gene product
20. Specific association of the gene product of PKD2 with the TRPC1 channel
21. From worm to man: Three subfamilies of TRP channels
22. 2+-permeable cation channel
23. Polycystin-1, the gene product of PKD1, induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells
24. Cellular and subcellular distribution of polycystin-2, the protein product of the PKD2 gene
25. Polycystin-1, the product of the polycystic kidney disease 1 gene, co-localizes with desmosomes in MDCK cells
26. Strong homophilic interactions of the Ig-like domains of polycystin-1, the protein product of an autosomal dominant polycystic kidney disease gene, PKD1
27. 2+ entry through store-operated channels in mouse sperm is initiated by egg ZP3 and drives the acrosome reaction
28. Interaction between RGS7 and polycystin
29. Compromised cytoarchitecture and polarized trafficking in autosomal dominant polycystic kidney disease cells