Routine experimental system for defining conditions used in photodynamic therapy and fluorescence photodetection of (non-) neoplastic epithelia

Journal of Biomedical Optics

Volumn 6, Issue 2, 2001, Pages 151-159

  Lange, N ^a   Vaucher, L ^a   Marti, A ^a   Etter, A L ^a   Gerber, P ^a   Van Den Bergh, H ^a   Jichlinski, P ^a   Kucera, P ^a  

^a EPFL   (Switzerland)

Author keywords

5 aminolevulinic acid derivatives; Fluorescence; PDT; Protoporphyrin IX; Tissue culture

Indexed keywords

AMINOLEVULINIC ACID; PHOTOSENSITIZING AGENT; PRODRUG; PROTOPORPHYRIN;

ANIMAL; ARTICLE; BLADDER; CELL DEATH; CULTURE TECHNIQUE; DRUG EFFECT; FLUORESCENCE MICROSCOPY; HUMAN; METABOLISM; MUCOSA; NEOPLASM; PARANASAL SINUS; PH; PHOTOCHEMOTHERAPY; RESPIRATORY TRACT MUCOSA; SHEEP; SWINE; TIME;

AMINOLEVULINIC ACID; ANIMALS; CELL DEATH; CULTURE TECHNIQUES; HUMANS; HYDROGEN-ION CONCENTRATION; MICROSCOPY, FLUORESCENCE; MUCOUS MEMBRANE; NEOPLASMS; PARANASAL SINUSES; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PRODRUGS; PROTOPORPHYRINS; RESPIRATORY MUCOSA; SHEEP; SWINE; TIME FACTORS; URINARY BLADDER;

BIOLOGICAL ORGANS; CELLS; ELECTRON MICROSCOPY; FLUORESCENCE; OPTICS; PHOTODYNAMIC THERAPY; SYNTHESIS (CHEMICAL); TISSUE CULTURE;

AMINOLEVULINIC ACID DERIVATIVE; FLUORESCENCE PHOTODETECTION; NEOPLASTIC EPITHELIA; ORGAN CULTURE; PROTOPORPHYRIN;

BIOMEDICAL ENGINEERING;

EID: 0035297584     PISSN: 10833668     EISSN: None     Source Type: Journal    
DOI: 10.1117/1.1352751     Document Type: Article

References (52)

1. Photodynamic therapy of esophageal carcinoma
2. Photodynamic therapy with verteporfin for choroidal neovascularization caused by age-related macular degeneration
3. Photodynamic therapy of subfoveal choroidal neovascularization-clinical and angiographic examples
4. Photodynamic therapy (PDT) and photodiagnosis (PD) using endogenous photosensitization induced by 5-aminolevulinic acid (ALA): Mechanisms and clinical results
5. Photodynamic therapy with topical application of 5-aminolevulinic acid in the treatment of actinic keratoses: An initial clinical study
6. Optimizing light dosimetry in photodynamic therapy of the bronchi by fluorescence spectroscopy
7. On the evolution of some endoscopic light delivery systems for photodynamic therapy
8. Photodynamic therapy with endogenous protoporphyrin IX: Basic principles and present clinical experience
9. 5-Aminolevulinic acid (ALA) for the fluorescence detection of bronchial tumors
10. Inhalation of 5-aminolevulinic acid: A new technique for fluorescence detection of early stage lung cancer
11. Clinical evaluation of a method for detecting superficial transitional cell carcinoma of the bladder by light-induced fluorescence of protoporphyrin IX following topical application of 5-Aminolevulinic acid: Preliminary results
12. Fluorescence photodetection of neoplastic urothelial lesions following intravesical instillation of 5-aminolevulinic acid
13. Early clinical experience with 5-aminolevulinic acid for the photodynamic therapy of superficial bladder cancer
14. Fluorescence detection of flat transitional cell carcinoma after intravesical instillation of aminolevulinic acid
15. Diagnosis of bladder carcinoma using protoporphyrin IX fluorescence induced by 5-aminolaevulinic acid
16. 5-Aminolevulinic acid-induced fluorescence endoscopy applied at secondary transurethral resection after conventional resection primary superficial bladder tumors
17. Intravesical instillation of 5-aminolevulinic acid: The fluorescent metabolite is limited to urothelial cells
18. Photodynamic ablation of high-grade dysplasia and early cancer in Barrett's esophagus by means of 5-aminolevulinic acid
19. Photodynamic therapy using 5-aminolevulinic acid for premalignant and malignant lesions of the oral cavity
20. Fluorescence staining of laryngeal neoplasms after topical application of 5-aminolevulinic acid: Preliminary results
21. Feasibility of photodynamic endometrial ablation without anesthesia
22. Localization of porphyrins in human basal cell carcinoma and normal tissue induced by topical application of 5-aminolevulinic acid
23. Biodistribution and phototoxicity of 5-aminolevulinic acid-induced PpIX in an orthotopic rat bladder tumor model
24. Lack of selectivity of protoporphyrin-IX fluorescence for basal-cell carcinoma after topical application of 5-aminolevulinic acid-Implications for photodynamic treatment
25. The importance of fluorescence distribution and kinetics of ALA-induced PpIX in the bladder in photodynamic therapy
26. 5-Aminolevulinic acid and its derivatives: Physical chemical properties and protoporphyrin IX formation in cultured cells
27. Topical application of 5-aminolevulinic acid, DMSO and EDTA: Protoporphyrin IX accumulation in skin and tumors of mice
28. Potential efficacy of a delta 5-aminolevulinic acid bioadhesive gel formulation for the photodynamic treatment of lesions of the gastrointestinal tract in mice
29. Iontophoretic delivery of ALA provides a quantitative model for ALA pharmacokinetics and PpIX phototoxicity in human skin
30. Prodrugs of 5-aminolevulinic acid for photodynamic therapy
31. Use of 5-aminolevulinic acid esters to improve photodynamic therapy on cells in culture
32. Photodetection of early human bladder cancer based on the fluorescence of 5-aminolevulinic acid hexylester-induced protoporphyrin IX: A pilot study
33. Topical photodynamic therapy in verrucae. A pilot study
34. Experimental bases for photodynamic laser therapy in chronic polyarthritis
35. Article 23 of Council Directive 86/609/EEC
36. Optimalisation of the formation and distribution of Protoporphyrin IX in the urothelium: An in vitro approach
37. Ion transport, ciliary activity and mechanosensitivity of sinusal mucosa: An in vitro study
38. Ion transport across the early chick embryo: I. Electrical measurements, ionic fluxes and regional heterogeneity
39. Preferential relative porphyrin enrichment in solar keratoses upon topical application of delta-aminolevulinic acid methylester
40. Three dimensional in vitro cocultivation of lung carcinoma cells with human bronchial organ culture as a model for bronchial carcinoma
41. In vivo fluorescence detection of ovarian cancer in the NuTu-19 epithelial cancer model using 5-aminolevulinic acid
42. 5-aminolevulinic acid, but not 5-aminolevulinic acid esters, is transported into adenocarcinoma cells by system BETA transporters
43. In vitro investigation of ALA-induced protoporphyrin IX
44. The influence of hypoxia and pH on aminolevulinic acid-induced photodynamic therapy in bladder cancer cells in vitro
45. pH-dependent formation of 5-aminolevulinic acid-induced protoporphyrin IX in fibrosarcoma cells
46. Chemical instability of 5-aminolevulinic acid used in the fluorescence diagnosis of bladder tumours
47. Benzoporphyrin-lipoprotein-mediated photodestruction of intraocular tumors
48. Photodynamic therapy of early squamous cell carcinoma with tetra(m-hydroxyphenyl)chlorin: Optimal drug-light interval
49. Comparison of phototoxicity mechanism between pulsed and continuous wave irradiation in photodynamic therapy
50. Flow cytometry study of the role of superoxide anion and hydrogen peroxide in cellular photodestruction with 5-aminolevulinic acid-induced protoporphyrin IX
51. Evidence for different mechanisms of EMT-6 tumor necrosis by photodynamic therapy with disulfonated aluminum phthalocyanine or photofrin: Tumor cell survival and blood flow
52. Light propagation in animal tissues in the wavelength range 373-825