Protein translocation: Is Hsp70 pulling my chain?

Current Biology

Volumn 9, Issue 20, 1999, Pages

  Jensen, Robert E ^a   Johnson, Arthur E ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; SACCHAROMYCES CEREVISIAE;

EID: 0033592642     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(00)80012-3     Document Type: Article

References (12)

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2. Voisine C, Craig EA, Zufall N, von Ahsen O, Pfanner N, Voos W: The protein import motor of mitochondria: unfolding and trapping of preproteins are distinct and separable functions of matrix Hsp70. Cell 1999, 97:565-574.
3. Matlack KE, Mothes W, Rapoport TA: Protein translocation: tunnel vision. Cell 1998, 92:381-390.
4. Schatz G, Dobberstein, B: Common principles of protein translocation across membranes. Science 1996, 271:1519-1526.
5. Pfanner N: Mitochondrial import: crossing the aqueous intermembrane space. Curr Biol 1998, 8:R262-R265.
6. BUkau B, Norwich AL: The Hsp70 and Hsp60 chaperone machines. Cell 1998, 92:351-366.
7. Glick BS: Can Hsp70 proteins act as force-generating motors? Cell 1995, 80:11-14.
8. Hamman BD, Chen JC, Johnson EE, Johnson AE: The aqueous pore through the translocon has a diameter of 40-60 Å during cotranslational protein translocation at the ER membrane. Cell 1997, 89:535-544.
9. Hamman BD, Hendershot LM, Johnson AE: BiP maintains the permeability barrier of the ER membrane by sealing the lumenal end of the translocon pore before and early in translocation. Cell 1998, 92:747-758.
10. Bömer U, Meijer M, Maarse AC, Honlinger A, Dekker PJ, Pfanner N, Rassow J: Multiple interactions of components mediating preprotein translocation across the inner mitochondrial membrane. EMBO J 1997, 16:2205-2216.
11. Kerscher O, Holder J, Srinivasan M, Leung RS, Jensen RE: The Tim54p-Tim22p complex mediates insertion of protein into the mitochondrial inner membrane. J Cell Biol 1997, 139:1663-1675.
12. Sirrenberg C, Bauer MF, Guiard B, Neupert W, Brunner M: Import of carrier proteins into the mitochondrial inner membrane mediated by TIM22. Nature 1996, 384:582-585.