Cyclophilin-promoted folding of mouse dihydrofolate reductase does not include the slow conversion of the late-folding intermediate to the active enzyme

Journal of Molecular Biology

Volumn 297, Issue 3, 2000, Pages 809-818

  Von Ahsen, Oliver ^a   Lim, Joo Hyun ^a   Caspers, Patrick ^b   Martin, Falk ^a   Schönfeld, Hans Joachim ^b   Rassow, Joachim ^a   Pfanner, Nikolaus ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Cyclophilin; Mouse DHFR; Prolyl isomerization; Protein folding

Indexed keywords

CYCLOPHILIN; DIHYDROFOLATE REDUCTASE; PROLINE;

ARTICLE; CATALYSIS; CHEMICAL REACTION KINETICS; CIS TRANS ISOMERISM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME DENATURATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; REACTION ANALYSIS;

ESCHERICHIA COLI; NEUROSPORA CRASSA;

EID: 0034737317     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.3574     Document Type: Article

References (43)

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