Separation of structural and dynamic functions of the mitochondrial translocase: Tim44 is crucial for the inner membrane import sites in translocation of tightly folded domains, but not of loosely folded preproteins

EMBO Journal

Volumn 17, Issue 15, 1998, Pages 4226-4237

  Bömer, Ulf ^a,b   Maarse, Ammy C ^c   Martin, Falk ^a   Geissler, Andreas ^a   Merlin, Alessio ^a   Schönfisch, Birgit ^a   Meijer, Michiel ^c   Pfanner, Nikolaus ^a   Rassow, Joachim ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b BAYER PHARMA AG   (Germany)

^c Institute for Molecular Cell Biology   (Netherlands)

Author keywords

Hsp70; Mitochondrial protein import; Tim44

Indexed keywords

CARRIER PROTEIN; MITOCHONDRIAL ENZYME; MUTANT PROTEIN; PROTEIN PRECURSOR;

ARTICLE; CONTROLLED STUDY; ENZYME STRUCTURE; MEMBRANE TRANSPORT; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE; STRUCTURE ACTIVITY RELATION;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; INTRACELLULAR MEMBRANES; MEMBRANE PROTEINS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MUTAGENESIS, INSERTIONAL; PROTEIN FOLDING; PROTEIN PRECURSORS; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE DELETION; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE;

EID: 0038889171     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.15.4226     Document Type: Article

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