Characterization of the mouse metal-regulatory-element-binding proteins, metal element protein-1 and metal regulatory transcription factor-1

Biochemical Journal

Volumn 353, Issue 3, 2001, Pages 591-601

  Larochelle, O ^a   Stewart, G ^a   Moffatt, P ^a   Tremblay, V ^a   Seguin, C ^a  

^a UNIVERSITÉ LAVAL   (Canada)

Author keywords

Inducible gene expression; Metalloregulatory transcription factors; Metallothionein gene; Phosphorylation; Splicing

Indexed keywords

BINDING PROTEIN; CADMIUM; DNA; METAL REGULATORY ELEMENT BINDING PROTEIN; METAL REGULATORY TRANSCRIPTION FACTOR 1; NUCLEAR PROTEIN; RIBONUCLEASE; RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ZINC ION;

ANIMAL CELL; ARTICLE; DNA BINDING; DNA SEQUENCE; ELECTROPHORETIC MOBILITY; GENETIC TRANSCRIPTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN PURIFICATION; ULTRAVIOLET IRRADIATION;

ANIMALS; BASE SEQUENCE; CHROMATOGRAPHY, GEL; DNA PRIMERS; DNA-BINDING PROTEINS; MICE; PHOSPHORYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 0035253152     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3530591     Document Type: Article

References (38)

1. Metallothionein in physiological and physiopathological processes
2. The elusive function of metallothioneins
3. Duplicated heavy metal control sequences of the mouse metallothionein-I gene
4. A 12-base-pair DNA motif that is repeated several times in metallothionein gene promoters confers metal regulation to a heterologous gene
5. Cloned transcription factor MTF-1 activates the mouse metallothionein-I promoter
6. The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression
7. Functional domains of the heavy metal-responsive transcription regulator MTF-1
8. Oxidative stress activates metal-responsive transcription factor-1 binding activity
9. Activation of metallothionein gene expression by hypoxia involves metal response elements and metal transcription factor-1
10. Characterization of the transcription factor MTF-1 from the Japanese pufferfish (Fugu rubripes) reveals evolutionary conservation of heavy metal stress response
11. Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor, MTF-1
12. Metallothionein gene regulation in mouse cells
13. Purification and characterization of a protein that binds to metal responsive elements of the human metallothionein II(A) gene
14. Interactions of the zinc regulated factor (ZiRF1) with the mouse metallothionein la promoter
15. A nuclear factor binds to the metal regulatory elements of the mouse gene encoding metallothionein-I
16. Purification of mouse MEP-1, a nuclear protein that binds to the metal regulatory elements of genes encoding metallothionein
17. Cell culture methods and induction of differentiation of embryonal carcinoma cell lines
18. Regulation in vitro of metallothionein gene binding factors
19. Rapid detection of octamer binding proteins with "mini-extracts", prepared from small number of cells
20. Detection of a nuclear protein that interacts with a metal regulatory element of the mouse metallothionein 1 gene
21. Guanidine methods for total RNA preparation
22. Ribonuclease protection assay
23. An improved T1/A ribonuclease protection assay
24. DNA sequencing with chain terminating inhibitors
25. The CTAB-DNA precipitation method: A common mini-scale preparation of template DNA from phagemids, phages or plasmids suitable for sequencing
26. Expression of the gene encoding metallothionein-3 in the organs of the reproductive system
27. A zinc-responsive factor interacts with a metal-regulated enhancer element (MRE) of the mouse metallothionein-I gene
28. Reversible activation of mouse metal response element-binding transcription factor 1 DNA binding involves zinc interaction with the zinc finger domain
29. Transcriptional activity and regulatory protein binding of metal-responsive elements of the human metallothionein-IIA gene
30. The DNA binding activity of metal response element-binding transcription factor-1 is activated in vivo and in vitro by zinc, but not by other transition metals
31. Cloning, chromosomal mapping and characterization of the human metal-regulatory transcription factor MTF-1
32. Constitutive and metal-inducible protein: DNA interactions at the mouse metallothionein I promoter examined by in vivo and in vitro footprinting
33. Zinc and cadmium can promote rapid nuclear translocation of metal response element-binding transcription factor-1
34. Role of redox potential and reactive oxygen species in stress signaling
35. Response of turnout cells to hypoxia: Role of p53 and NF-κB
36. p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducibie factor 1α (HIF-1α) and enhance the transcriptional activity of HIF-1
37. Cadmium-mediated activation of the metal response element in human neuroblastoma cells lacking functional metal response element-binding transcription factor-1