Protective effect of stiripentol on acetaminophen-induced hepatotoxicity in rat

Toxicology and Applied Pharmacology

Volumn 170, Issue 3, 2001, Pages 145-152

  Tran, Agnès ^a   Tréluyer, Jean Marc ^a   Rey, Elisabeth ^a   Barbet, Jacques ^b   Ferracci, Géraldine ^a   D'Athis, Philippe ^a   Vincent, Jean ^c   Pons, Gérard ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b HÔPITAL SAINT VINCENT DE PAUL   (France)

^c Service de Pharmacologie   (France)

Author keywords

Acetaminophen intoxication; Cytochrome P450; Drug metabolism; Rat; Stiripentol

Indexed keywords

ACETYLCYSTEINE; AMINOTRANSFERASE; ANTICONVULSIVE AGENT; BENZOQUINONE DERIVATIVE; CYSTEINE; CYTOCHROME P450 1A2; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; GLUTATHIONE; PARACETAMOL; STIRIPENTOL;

AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG GLUCURONIDATION; DRUG METABOLISM; DRUG OXIDATION; ENZYME INHIBITION; LIVER NECROSIS; LIVER TOXICITY; MALE; MORTALITY; NONHUMAN; RAT; SULFATION;

ANIMALIA;

EID: 0035251564     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.2000.9091     Document Type: Article

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