Increasing endothelial cell permeability improves the efficiency of myocyte adenoviral vector infection

Journal of Gene Medicine

Volumn 3, Issue 1, 2001, Pages 42-50

  Nevo, Nathalie ^a,b   Chossat, Nathalie ^a   Gosgnach, Willy ^a   Logeart, Damien ^a   Mercadier, Jean Jacques ^a   Michel, Jean Baptiste ^a  

^a INSERM   (France)

^b BICHAT HOSPITAL   (France)

Author keywords

Adenoviral vector; Cardiac myocytes; Endothelium; Gene therapy; Permeability; Thrombin

Indexed keywords

THROMBIN;

ADENOVIRUS; ANIMAL; ARTICLE; CAPILLARY PERMEABILITY; CELL CULTURE; CYTOLOGY; DRUG EFFECT; GENE TRANSFER; GENE VECTOR; GENETICS; HUMAN; MALE; METABOLISM; RAT; SMOOTH MUSCLE; VASCULAR ENDOTHELIUM; WISTAR RAT;

ADENOVIRIDAE; ANIMALS; CAPILLARY PERMEABILITY; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; MALE; MUSCLE, SMOOTH; RATS; RATS, WISTAR; THROMBIN;

EID: 0035236496     PISSN: 1099498X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-2254(2000)9999:9999<::AID-JGM149>3.0.CO;2-A     Document Type: Article

References (34)

1. Del Monte F, Harding SE, Schmidt U, et al. Restoration of contractile function in isolated cardiomyocytes from failing human hearts by gene transfer of SERCA2. Circulation 1999; 100: 2308-2311.
2. Maurice JP, Koch WJ. Potential future therapies for heart failure: gene transfer of beta-adrenergic signaling components, Coron Artery Dis 1999; 10: 401-405.
3. Kirshenbaum LA, MacLellan WR, Mazur W, et al. Highly efficient gene transfer into adult ventricular myocytes by recombinant adenovirus. J Clin Invest 1993; 92: 381-387.
4. Kass-Eisler A, Falck-Pedersen E, Alvira M, et al. Quantitative determination of adenovírus-mediated gene delivery to rat cardiac myocytes in vitro and in vivo. Proc Natl Acad Sci U S A 1993; 90: 11498-11502.
5. Stratford-Perricaudet LD, Makeh I, Perricaudet M, et al. Widespread long-term gene transfer to mouse skeletal muscles and heart. J Clin Invest 1992; 90: 626-630.
6. Huard J, Lochmuller H, Acsadi G, et al. The route of administration is a major determinant of the transduction efficiency of rat tissues by adenoviral recombinants. Gene Ther 1995; 2: 107-115.
7. French BA, Mazur W, Geske RS, et al. Direct in vivo gene transfer into porcine myocardium using replication-deficient adenoviral vectors. Circulation 1994; 90: 2414-2424.
8. Gizman RJ, Lemarchand P, Crystal RG, et al. Efficient gene transfer into myocardium by direct injection of adenovirus vectors. Circ Res 1993; 73: 1202-1207.
9. Barr E, Carroll J, Kalynych AM, et al. Efficient catheter-mediated gene transfer into the heart using replication-defective adenovirus. Gene Ther 1994; 1: 51-56.
10. Mühlhauser J, Jones M, Yamada I, et al. Safety and efficacy of in vivo gene transfer into the porcine heart with replication-deficient, recombinant adenovirus vectors. Gene Ther 1996; 3: 145-153.
11. Fechner H, Haack A, Wang H, et al. Expression of coxsackie adenovirus receptor and alpha-integrin does not correlate with adenovector targeting in vivo indicating anatomical vector barriers. Gene Ther 1999; 6: 1520-1535.
12. van Hinsbergh WM, Endothelial permeability for macromolecules. Mechanistic aspects of pathophysiological modulation. Arterioscler Thromb Vasc Biol 1997; 17: 1018-1023.
13. Lum H, Malik AB. Regulation of vascular endothelial barrier function. Am J Physiol 1994; 267: L223-L241.
14. Jaffe EA, Nachman RL, Becker CG, et al. Culture of human endothelial cells derived form umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest 1973; 52: 2745-2756.
15. Wagner DD, Marder VJ. Biosynthesis of von Willebrand protein by human endotheial cells: processing steps and their intracellular localization. J Cell Biol 1984; 99: 2123-2130.
16. Pardridge WM, Triguero D, Yang J, et al. Comparison of in vitro and in vivo models of drug transcytosis through the blood-brain barrier. J Pharmacol Exp Ther 1990; 253: 884-891.
17. Graham FL, Smiley J, Russell WC, et al. Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J Gen Virol 1977; 36: 59-74.
18. Rucker-Martin C, Henaff M, Hatem SN, et al. Early redistribution of plasma membrane phosphatidylserine during apoptosis of adult rat ventricular myocytes in vitro. Basic Res Cardiol 1999; 94: 171-179.
19. van Nieuw Amerongen GP, Draijer R, Vermeer MA, et al. Transient and prolonged increase in endothelial permeability induced by histamine and thrombin: role of protein kinases, calcium, and RhoA. Circ Res 1998; 83: 1115-1123.
20. Langeler EG, van Hinsbergh VW. Characterization of an in vitro model to study the permeability of human arterial endothelial cell monolayers. Thromb Haemost 1988; 60: 240-246.
21. Casnocha SA, Eskin SG, Hall ER, et al. Permeability of human ertdothelial monolayers: effect of vasoactive agonists and cAMP. J Appl Physiol 1989; 67: 1997-2005.
22. Milton SG, Knutson VP. Comparison of the function of the tight junctions of endothelial cells and epithelial cells in regulating the movement of electrolytes and macromolecules across the cell monolayer. J Cell Physiol 1990; 144: 498-504.
23. Ikeda K, Utoguchi N, Makimoto H, et al. Different reactions of aortic and venular endothelial cell monolayers to histamine on macromolecular permeability: role of cAMP, cytosolic Ca2+ and F-actin. Inflammation 1999; 23: 87-97.
24. Oliver JA. Adenylate cyclase and protein kinase C mediate opposite actions on endothelial junctions. J Cell Physiol 1990; 145: 536-542.
25. Draijer R, Atsma DE, van der Laarse A, et al. cGMP and nitric oxide modulate thrombin-induced endothelial permeability. Regulation via different pathways in human aortic and umbilical vein endothelial cells. Circ Res 1995; 76: 199-208.
26. Rabiet MJ, Plantier JL, Rival Y, et al. Thrombin-induced increase in endothelial permeability is associated with changes in cell-to-cell junction organization. Arterioscler Thromb Vase Biol 1996; 16: 488-496.
27. Vouret-Craviari V, Boquet P, Pouyssegur J, et al. Regulation of the actin cytoskeleton by thrombin in human endothelial cells: role of Rho proteins in endothelial barrier function. Mol Biol Cell 1998; 9: 2639-2653.
28. Lemarchand P, Jaffe HA, Danel C, et al. Adenovirus-mediated transfer of a recombinant human alpha 1-antitrypsin cDNA to human endothelial cells. Proc Natl Acad Sci U S A 1992; 89: 6482-6486.
29. Schulick AH, Dong G, Newman KD, et al. Endothelium-specific in vivo gene transfer. Circ Res 1995; 77: 475-485.
30. Merrick AF, Shewring LD, Sawyer GJ, et al. Comparison of adenovirus gene transfer to vascular endothelial cells in cell culture, organ culture, and in vivo. Transplantation 1996; 62: 1085-1089.
31. Rekhter MD, Simari RD, Work CW, et al. Gene transfer into normal and atherosclerotic human blood vessels. Circ Res 1998; 82: 1243-1252.
32. Schnitzer J. Update on the cellular and molecular basis of capillary permeability. Trends Cardiovasc Med 1993; 3: 124-130.
33. Greber UF, Willetts M, Webster P, et al. Stepwise dismantling of adenovirus 2 during entry into cells. Cell 1993; 75: 477-486.
34. Logeart D, Hatem SN, Rücker-Martin C, et al. Highly efficient adenovirus-mediated gene transfer to cardiac myocytes following single-pass coronary delivery. Hum Gene Ther 2000; 11: 1015-1022.