Atomic force microscopy imaging of DNA-cationic liposome complexes optimised for gene transfection into neuronal cells

Journal of Gene Medicine

Volumn 3, Issue 1, 2001, Pages 72-81

  Wangerek, Louise A ^a,b   Dahl, Hans Henrik M ^a,b   Senden, Tim J ^c   Carlin, John B ^b,d   Jans, David A ^e   Dunstan, Dave E ^b   Ioannou, Panayiotis A ^a,b   Williamson, Robert ^a,b   Forrest, Susan M ^a,b  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^d MURDOCH CHILDREN'S RESEARCH INSTITUTE   (Australia)

^e AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

Atomic force microscopy; Cationic liposome; Lipoplex; Neuronal cells; Transfection

Indexed keywords

CATION; DNA; LIPOSOME;

ANIMAL; ARTICLE; ATOMIC FORCE MICROSCOPY; CHO CELL; GENETIC TRANSFECTION; GENETICS; HAMSTER; LIGHT; METABOLISM; NERVE CELL; RADIATION SCATTERING;

ANIMALS; CATIONS; CHO CELLS; CRICETINAE; DNA; LIGHT; LIPOSOMES; MICROSCOPY, ATOMIC FORCE; NEURONS; SCATTERING, RADIATION; TRANSFECTION;

EID: 0035228185     PISSN: 1099498X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-2254(200101/02)3:1<72::AID-JGM157>3.0.CO;2-M     Document Type: Article

References (34)

1. Felgner PL, Gadek TR, Holm M, et al. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc Natl Acad Sd U S A 1987; 84: 7413-7417.
2. Caplen NJ, Kinrade E, Sorgi F, et al. In vitro liposome-mediated DNA transfection of epithelial cell lines using the cationic liposome DC-Chol/DOPE. Gene Ther 1995; 2: 603-613.
3. Griffiths T, Russell M, Froning K, et al, The PerFect lipid optimizer kit for maximizing lipid-mediated transfection of eukaryotic cells. Biotechniques 1997; 22: 982-987.
4. Felgner JH, Kumar R, Sridhar CN, et al. Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations. J Biol Chem 1994; 269: 2550-2561.
5. Mortimer I, Tam P, MacLachlan I, et al. Cationic lipid-mediated transfection of cells in culture requires mitotic activity. Gene Ther 1999; 6: 403-411.
6. Holt CE, Garlick N, Cornel E. Lipofection of cDNAs in the embryonic vertebrate central nervous system. Neuron 1990; 4: 203-214.
7. Ono T, Fujino Y, Tsuchiya T, et al. Plasmid DNAs directly injected into mouse brain with lipofectin can be incorporated and expressed by brain cells. Neurosci Lett 1990; 117: 259-263.
8. Roessler BJ, Davidson BL. Direct plasmid mediated transfection of adult murine brain cells in vivo using cationic liposomes. Neurosci Lett 1994; 167: 5-10.
9. McQuillin A, Murray KD, Etheridge CJ, et al. Optimization of liposome mediated transfection of a neuronal cell line. Neuroreport 1997; 8: 1481-1484.
10. Yang K, Faustinella F, Xue JJ, et al. Optimizing liposome-mediated gene transfer in primary rat septo-hippocampal cell cultures. Neurosci Lett 1994; 182: 287-290.
11. Zou L, Huang L, Hayes R, et al. Liposome-mediated NGF gene transfection following neuronal injury: potential therapeutic applications. Gene Ther 1999; 6: 994-1005.
12. Gershon H, Ghirlando R, Guttman SB, et al. Mode of formation and structural features of DNA-cationic liposome complexes used for transfection. Biochemistry 1993; 32: 7143-7151.
13. Sternberg B, Sorgi FL, Huang L. New structures in complex formation between DNA and cationic liposomes visualized by freeze-fracture electron microscopy. FEBS Lett 1994; 356: 361-366.
14. Gustafsson J, Arvidson G, Karlsson G, et al. Complexes between cationic liposomes and DNA visualized by cryo-TEM. Biochim Biophys Acta 1995; 1235: 305-312.
15. Wolfert MA, Seymour LW. Atomic force microscopic analysis of the influence of the molecular weight of poly(L)lysine on the size of polyelectrolyte complexes formed with DNA. Gene Ther 1996; 3: 269-273.
16. Wolfert MA, Schacht EH, Toncheva V, et al. Characterization of vectors for gene therapy formed by self-assembly of DNA with synthetic block co-polymers. Hum Gene Ther 1996; 7: 2123-2133.
17. Wheeler CJ, Sukhu L, Yang G, et al. Converting an alcohol to an amine in a cationic lipid dramatically alters the co-lipid requirement, cellular transfection activity and the ultrastructure of DNA-cytofectin complexes. Biochim Biophys Acta 1996; 1280: 1-11.
18. Dunlap DD, Maggi A, Soria MR, et al. Nanoscopic structure of DNA condensed for gene delivery. Nucleic Acids Res 1997; 25: 3095-3101.
19. Allen MJ, Bradbury EM, Balhorn R. AFM analysis of DNA-protamine complexes bound to mica. Nucleic Acids Res 1997; 25: 2221-2226.
20. Fang Y, Hoh JH. Early intermediates in spermidine-induced DNA condensation on the surface of mica. J Am Chem Soc 1998; 120: 8903-8909.
21. Hansma HG, Golan R, Hsieh W, et al. DNA condensation for gene therapy as monitored by atomic force microscopy. Nucleic Acids Res 1998; 26: 2481-2487.
22. Kawaura C, Noguchi A, Furuno T, et al. Atomic force microscopy for studying gene transfection mediated by cationic liposomes with a cationic cholesterol derivative. FEBS Lett 1998; 421: 69-72.
23. Feigner PL, Barenholz Y, Behr JP, et al. Nomenclature for synthetic gene delivery systems. Hum Gene Ther 1997; 8: 511-512.
24. Li S, Tseng WC, Stolz DB, et al. Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: implications for intravenous lipofection. Gene Ther 1999; 6: 585-594.
25. Hui SW, Langner M, Zhao YL, et al. The role of helper lipids in cationic liposome-mediated gene transfer. Biophys J 1996; 71: 590-599.
26. Farhood H, Serbina N, Huang L. The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer. Biochim Biophys Acta 1995; 1235: 289-295.
27. Mislick KA, Baldeschwieler JD. Evidence for the role of proteoglycans in cation-mediated gene transfer. Proc Natl Acad Sci U S A 1996; 93: 12349-12354.
28. Mounkes LC, Zhong W, Cipres-Palacin G, et al. Proteoglycans mediate cationic liposome-DNA complex-based gene delivery in vitro and in vivo. J Biol Chem 1998; 273: 26164-26170.
29. Fasbender A, Marshall J, Moninger TO, et al. Effect of co-lipids in enhancing cationic lipid-mediated gene transfer in vitro and in vivo. Gene Ther 1997; 4: 716-725.
30. Norton WT, Poduslo SE. Neuronal perikarya and astroglia of rat brain: chemical composition during myelination. J Lipid Res 1971; 12: 84-90.
31. Chakravarthy BR, Spence MW, Clarke JT, et al. Rapid isolation of neuroblastoma plasma membranes on Percoll gradients. Characterization and lipid composition. Biochim Biophys Acta 1985; 812: 223-233.
32. Williams TP, McGee Jr R. The effects of membrane fatty acid modification of clonal pheochromocytoma cells on depolarization-dependent exocytosis. J Biol Chem 1982; 257: 3491-3500.
33. Sinensky M. Adaptive alteration in phospholipid composition of plasma membranes from a somatic cell mutant defective in the regulation of cholesterol biosynthesis. J Cell Biol 1980; 85: 166-169.
34. Hansma PK, Elings VB, Marti O, et al. Scanning tunneling microscopy and atomic force microscopy: application to biology and technology. Science 1988; 242: 209-216.