The MHC locus controls size variations in the CD4 compartment of the mouse thymus

Immunogenetics

Volumn 53, Issue 8, 2001, Pages 662-668

  Duarte, N ^a   Penha Goncalves C ^a  

^a INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

Author keywords

H2 Ea; Homeostasis; MHC; QTL; Thymocytes

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; GENE LOCUS; IMMUNOLOGICAL TOLERANCE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; THYMUS;

AGE FACTORS; ANIMALS; CD4 LYMPHOCYTE COUNT; CD4-POSITIVE T-LYMPHOCYTES; CHROMOSOME MAPPING; CHROMOSOMES; CROSSES, GENETIC; FEMALE; FLOW CYTOMETRY; LOD SCORE; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; QUANTITATIVE TRAIT, HERITABLE; THYMUS GLAND;

ANIMALIA; RODENTIA;

EID: 0035217869     PISSN: 00937711     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00251-001-0377-9     Document Type: Article

References (23)

1. T-cell-receptor affinity and thymocyte positive selection
2. Genetic control of the CD4/CD8 T-cell ratio in humans
3. Thymocyte selection: Not by TCR alone
4. Glucocorticoids in T cell development and function
5. Thymocyte maturation is regulated by the activity of the helix-loop-helix protein, E47
6. Structure and polymorphism of murine and human class II major histocompatibility antigens
7. The thymus selects the useful, neglects the useless and destroys the harmful
8. Positive selection of immature alpha beta T cells
9. A dominant role for the thymus and MHC genes in determining the peripheral CD4/CD8T cell ratio in the rat
10. Correlating notch signaling with thymocyte maturation
11. Regulation of thymic development by neprilysin inhibition
12. Differential chemotactic behavior of developing T cells in response to thymic chemokines
13. Genetic control of T-cell subset representation in inbred mice
14. Mapping mendelian factors underlying quantitative traits using RFLP linkage maps
15. MAPMAKER: An interactive computer package for constructing primary genetic linkage maps of experimental and natural populations
16. Several mechanisms can account for defective E alpha gene expression in different mouse haplotypes
17. Thymic lineage commitment rather than selection causes genetic variations in size of CD4 and CD8 compartments
18. MHC class I is required for peripheral accumulation of CD8+ thymic emigrants
19. Resolution of quantitative traits into Mendelian factors by using a complete linkage map of restriction fragment length polymorphisms
20. +) thymocytes in normal and genetically modified mice
21. + T cells
22. Lymphocyte life-span and memory
23. + T cells, but affect their long-term life span