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Volumn 37, Issue 9, 2001, Pages 587-594

Pitavastatin (NK-104), a new HMG-CoA reductase inhibitor

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; CERIVASTATIN; CHOLESTEROL; CYTOCHROME P450 3A4; DIAZEPAM; DIGITOXIN; FIBRIC ACID DERIVATIVE; FUROSEMIDE; GEMFIBROZIL; GLIBENCLAMIDE; IBUPROFEN; INTERMEDIATE DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEVINOLIN; NICOTINIC ACID; NITRENDIPINE; PHENYLBUTAZONE; PHENYTOIN; PITAVASTATIN; PRAVASTATIN; SIMVASTATIN; STATINE DERIVATIVE; TOLBUTAMIDE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN; WARFARIN;

EID: 0035204867     PISSN: 16993993     EISSN: 16994019     Source Type: Journal    
DOI: 10.1358/dot.2001.37.9.844218     Document Type: Review
Times cited : (10)

References (39)
  • 2
    • 0026593243 scopus 로고
    • Serum cholesterol, blood pressure, cigarette smoking, and death from coronary heart disease. Overall findings and differences by age for 316,099 white men
    • Multiple Risk Factor Intervention Trial Research Group
    • (1992) Arch Intern Med , vol.152 , pp. 56-64
    • Neaton, J.D.1    Wentworth, D.2
  • 4
    • 0021350001 scopus 로고
    • The Lipid Research Clinics Coronary Primary Prevention Trial Results. I. Reduction in incidence of coronary heart disease
    • (1984) JAMA , vol.251 , pp. 351-364
  • 5
    • 0023232216 scopus 로고
    • Helsinki Heart Study: Primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease
    • (1987) N Engl J Md , vol.317 , pp. 1237-1245
    • Frick, M.H.1    Elo, O.2    Haapa, K.3
  • 6
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 7
    • 0032487931 scopus 로고    scopus 로고
    • Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group
    • (1998) N Engl J Med , vol.339 , pp. 1349-1357
  • 8
    • 0342981862 scopus 로고    scopus 로고
    • The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial Investigators
    • (1996) N Engl J Med , vol.335 , pp. 1001-1009
    • Sacks, F.M.1    Pfeffer, M.A.2    Moye, L.A.3
  • 9
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
    • West of Scotland Coronary Prevention Study Group
    • (1995) N Engl J Med , vol.333 , pp. 1301-1307
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3
  • 10
    • 0032572086 scopus 로고    scopus 로고
    • Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: Results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study
    • (1998) JAMA , vol.279 , pp. 1615-1622
    • Downs, J.R.1    Clearfield, M.2    Weis, S.3
  • 11
    • 0035897696 scopus 로고    scopus 로고
    • Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 18
    • 0032799925 scopus 로고    scopus 로고
    • NK-104, a potent new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, enhances posttranslational catabolism of apolipoprotein B-100 and inhibits secretion of apolipoprotein B-100 and triacylglycerols from HepG2 cells
    • (1999) Curr Ther Res , vol.60 , pp. 423-434
    • Yanagita, T.1    Hara, E.2    Yotsumoto, H.3
  • 26
    • 0033694827 scopus 로고    scopus 로고
    • Lipid-lowering and antiatherosclerotic effect of NK-104, a potent 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, and Watanabe heritable hyperlipidemic rabbits
    • (2000) Arzneim-Forsch Drug Res , vol.50 , pp. 995-1003
    • Suzuki, H.1    Yamazaki, H.2    Aoki, T.3
  • 30
    • 0032443604 scopus 로고    scopus 로고
    • Antigenicity studies of (+)-monocalcium bis [3R, 5S, 6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3, 5-dihydroxy-6-heptenoate] (NK-104) in guinea pigs
    • (1998) Pharmacometrics , vol.56 , pp. 179-182
    • Ichinohe, H.1    Yoshimura, H.2    Amano, Y.3
  • 31
    • 0032419622 scopus 로고    scopus 로고
    • Single dose toxicity studies of (+)-monocalcium bis[(3R, 5S, 6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3, 5-dihydroxy-6-heptenoate] (NK-104) in rats and dogs
    • (1998) Pharmacometrics , vol.56 , pp. 67-72
    • Shibuta, T.1    Kato, Y.2    Akiba, T.3
  • 33
    • 0032431617 scopus 로고    scopus 로고
    • A 12-month oral toxicity study of (+)-monocalcium bis[(3R, 5S, 6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3, 5-dihydroxy-6-heptenoate](NK- 104) in dogs followed by a 2-month recovery test
    • (1998) Pharmacometrics , vol.56 , pp. 101-130
    • Shibuta, T.1    Kato, Y.2    Amano, Y.3
  • 34
    • 0032446516 scopus 로고    scopus 로고
    • Reproductive and developmental toxicity studies of (+)-monocalcium bis[(3R, 5S, 6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3, 5-dihydroxy-6-heptenoate] (NK-104): 1. Fertility study in rats by oral administration
    • (1998) Pharmacometrics , vol.56 , pp. 131-138
    • Kamijima, M.1    Hirasawa, S.2    Sekitani, T.3
  • 35
    • 0032431345 scopus 로고    scopus 로고
    • Reproductive and developmental toxicity studies of (+)-monocalcium bis [(3R, 5S, 6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3, 5-dihydroxy-6-heptenoate] (MK 104): 2. Teratogenicity study in rats by oral administration
    • (1998) Pharmacometrics , vol.56 , pp. 139-152
    • Nishigaki, K.1    Moriwaki, T.2    Akiba, T.3
  • 36
    • 0032433769 scopus 로고    scopus 로고
    • Reproductive and developmental toxicity study of (+)-monocalcium bis[(3R, 5S, 6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3, 5-dihydroxy-6-heptenoate] (NK-104): 3. Teratogenicity study in rabbits by oral administration
    • (1998) Pharmacometrics , vol.56 , pp. 153-159
    • Nishigaki, K.1    Moriwaki, T.2    Akiba, T.3
  • 37
    • 0032438944 scopus 로고    scopus 로고
    • Reproductive and developmental toxicity studies of (+)-monocalcium bis[(3R, 5S, 6R)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3, 5-dihydroxy-6-heptenoate] (NK-104): 4. Perinatal and postnatal study in rats by oral administration
    • (1998) Pharmacometrics , vol.56 , pp. 161-177
    • Nishigaki, K.1    Moriwaki, T.2    Akiba, T.3
  • 39
    • 0033984189 scopus 로고    scopus 로고
    • Effects of NK-104, a new hydroxymethylglutaryl-coenzyme reductase inhibitor, on low-density lipoprotein cholesterol in heterozygous familial hypercholesterolemia
    • (2000) Am J Cardiol , vol.85 , pp. 178-183
    • Kajinami, K.1    Koizumi, J.2    Ueda, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.