Identification of metabolites of NK-104, an HMG-CoA reductase inhibitor, in rat, rabbit and dog bile

Biological and Pharmaceutical Bulletin

Volumn 22, Issue 2, 1999, Pages 142-150

  Kojima, Junji ^a   Fujino, Hideki ^a   Abe, Haruyasu ^a   Yosimura, Mitsuo ^a   Kanda, Hiroyasu ^b   Kimata, Hideki ^a  

^a KOWA COMPANY LTD   (Japan)

^b NISSAN CHEMICAL INDUSTRIES LTD   (Japan)

Author keywords

Biliary metabolite; Electrospray ionization LC MS; NK 104; Proton NMR

Indexed keywords

DRUG METABOLITE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PITAVASTATIN;

ANIMAL TISSUE; ARTICLE; BILE; DOG; DRUG CONJUGATION; DRUG TRANSFORMATION; FATTY ACID OXIDATION; HYDROXYLATION; INTRAVENOUS DRUG ADMINISTRATION; ISOMERISM; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RABBIT; RAT;

EID: 0032914056     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.22.142     Document Type: Article

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