Mutations in the second largest subunit of RNA polymerase II cause 6-azauracil sensitivity in yeast and increased transcriptional arrest in vitro

Journal of Biological Chemistry

Volumn 271, Issue 12, 1996, Pages 6866-6873

  Powell, Wade ^a   Reines, Daniel ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZAURACIL; RNA POLYMERASE II;

AMINO ACID SUBSTITUTION; ARTICLE; CELL GROWTH; ENZYME SUBUNIT; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; RNA CLEAVAGE; RNA TRANSLATION;

HYDROLYSIS; KINETICS; MICROBIAL SENSITIVITY TESTS; POINT MUTATION; RNA POLYMERASE II; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION, GENETIC; URACIL;

EUKARYOTA; PROKARYOTA;

EID: 0029862975     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.12.6866     Document Type: Article

References (55)

1. Archambault, J., Lacroute, F., Ruet, A., and Friesen, J D (1992) Mol. Cell. Biol. 12, 4142-4152
2. Aso, T., Lane, W S., Conaway, J. W., and Conaway, R C (1995) Science 269, 1439-1443
3. Bartholomew, B., Dahmus, M. E., and Meares, C F (1986) J. Biol. Chem. 261, 14226-14231
4. Bengal, E., Flores, O., Krauskopf, A., Reinberg, D., and Aloni, Y (1991) Mol Cell. Biol 11, 1195-1206
5. Chen, Y., Weeks, J., Mortin, M. A., and Greenleaf, A. L. (1993) Mol. Cell. Biol. 13, 4214-4222
6. Christie, K. R., Awrey, D E., Edwards, A. M., and Kane, C. M. (1994) J. Biol Chem 269, 936-943
7. Conaway, J. W , and Conaway, R C. (1990) Science 248, 1550-1553
8. Conaway, R. C., Reines, D., Garrett, K. P., Powell, W., and Conaway, J. W (1996) Methods Enzymol , in press
9. Coulter, D. E., and Greenleaf, A. L (1985) J Biol. Chem. 260, 13190-13198
10. Dedrick, R L., and Chamberlin, M J (1985) Biochemistry 24, 2245-2253
11. Dedrick, R. L., Kane, C. M., and Chamberlin, M. J (1987) J. Biol. Chem. 262, 9098-9108
12. Deuschle, U , Hipskind, R. A., and Bujard, H. (1990) Science 248, 480-483
13. Donahue, B. A , Yin, S., Taylor, J.-S., Reines, D., and Hanawalt, P. C. (1994) Proc. Natl Acad. Sci U. S. A. 91, 8502-8506
14. Edwards, A. M., Darst, S. A., Feaver, W. J., Thompson, N E., Burgess, R R., and Kornberg, R. D. (1990) Proc. Natl. Acad. Sci. U. S A. 87, 2122-2126
15. Eilat, D., Hochberg, M., Fishel, R., and Laskov, R. (1982) Proc. Natl. Acad. Sci U. S. A. 79, 3818-3822
16. Exinger, G , and Lacroute, F. (1992) Curr. Genet. 22, 9-11
17. Flores, O , Maldonado, E., and Reinberg, D. (1989) J. Biol. Chem. 264, 8913-8921
18. Gu, W., and Reines, D. (1995a) J. Biol. Chem. 270, 11238-11244
19. Gu, W., and Reines, D. (1995b) J. Biol. Chem. 270, 30441-30447
20. Gu, W., Powell, W., Mote, J., Jr., and Reines, D. (1993) J. Biol. Chem. 268, 25604-25616
21. Guo, H., and Price, D. H. (1993) J. Biol. Chem 268, 18762-18770
22. Hodo, H. G., III, and Blatti, S. P (1977) Biochemistry 16, 2334-2343
23. Iwabe, N , Kuma, K., Kishino, H., Hasegawa, M., and Miyata, T. (1991) J. Mol. Evol. 32, 70-78
24. Izban, M. G , and Luse, D. S. (1991) Genes & Dev. 5, 683-696
25. Izban, M. G., and Luse, D. S. (1992) J. Biol. Chem. 267, 13647-13655
26. Izban, M. G., and Luse, D. S. (1993a) J. Biol. Chem. 268, 12864-12873
27. Izban, M. G., and Luse, D. S. (1993b) J. Biol. Chem. 268, 12874-12885
28. Jin, D. J., and Gross, C. A. (1991) J. Biol. Chem. 266, 14478-14485
29. Kadesch, T. R., and Chamberlin, M. J (1982) J Biol. Chem. 257, 5286-5295
30. Kane, C. M. (1994) in Transcription (Conaway, R., and Conaway, J. W., eds) pp. 279-296, Raven Press, Ltd., New York
31. Kuhn, A , Bartsch, I., and Grummt, I. (1990) Nature 344, 559-562
32. Mote, J., Jr., Ghanouni, P., and Reines, D. (1994) J. Mol. Biol. 236, 725-737
33. Nakanishi, T., Nakuno, A., Nomura, K., Sekimizu, K., and Natori, S. (1992) J. Biol. Chem 267, 13200-13204
34. Nudler, E., Kashlev, M., Nikitorov, V., and Goldfarb, A. (1995) Cell 81, 351-357
35. Price, D. H., Sluder, A., and Greenleaf, A. L. (1989) Mol. Cell. Biol. 9, 1465-1475
36. Reines, D. (1991) J. Biol Chem 266, 10510-10517
37. Reines, D. (1994) in Transcription (Conaway, R., and Conaway, J. W., eds) pp. 263-278, Raven Press, Ltd., New York
38. Reines, D., and Mote, J., Jr. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 1917-1921
39. Reines, D., Wells, D., Chamberlin, M. J., and Kane, C. M. (1987) J. Mol. Biol. 196, 299-312
40. Rudd, M. D., Izban, M. G., and Luse, D. S. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 8057-8061
41. Ruet, A., Sentenac, A., and Fromageot, P. (1978) Eur. J. Biochem. 90, 325-330
42. Sawadogo, M., Sentenac, A., and Fromageot, P. (1980) J. Biol. Chem. 255, 12-15
43. Scafe, C , Martin, C., Nonet, M., Podos, S., Okamura, S., and Young, R. A. (1990a) Mol. Cell Biol. 10, 1271-1275
44. Scafe, C., Nonet, M., and Young, R. A. (1990b) Mol. Cell. Biol. 10, 1010-1016
45. Schwartz, L B , Sklar, V. E F., Jaehning, J. A., Weinmann, R , and Roeder, R. G. (1974) J. Biol. Chem. 249, 5889-5897
46. Shaaban, S. A., Krupp, B M , and Hall, B. D. (1995) Mol. Cell. Biol. 15, 1467-1478
47. Sidow, A., and Thomas, W. K. (1994) Curr. Biol. 4, 596-603
48. SivaRaman, L., Reines, D., and Kane, C. M. (1990) J. Biol. Chem. 265, 14554-14560
49. Sweetser, D., Nonet, M., and Young, R. A. (1987) Proc. Natl. Acad Sci U. S. A. 84, 1192-1196
50. Tan, S , Conaway, R. C., and Conaway, J. W. (1995) Proc. Natl. Acad. Sci. U. S A. 84, 6042-6046
51. Thompson, N. E , Steinberg, T. H., Aronson, D. B., and Burgess, R R (1989) J. Biol. Chem. 264, 11511-11520
52. Treich, I , Carles, C , Sentenac, A., and Riva, M. (1992) Nucleic Acids Res. 20, 4721-4725
53. Wang, D , Meier, T I., Chan, C. L., Feng, G., Lee, D. N , and Landick, R (1995) Cell 81, 341-350
54. Wiest, D K., and Hawley, D K. (1990) Mol. Cell. Biol. 10, 5782-5792
55. Wiest, D K , Wang, D., and Hawley, D. K (1992) J. Biol. Chem. 267, 7733-7744