Comparison between IgG and F(ab′)2 polyvalent antivenoms: Neutralization of systemic effects induced by Bothrops asper venom in mice, extravasation to muscle tissue, and potential for induction of adverse reactions

Toxicon

Volumn 39, Issue 6, 2001, Pages 793-801

  Leon G ^a   Monge, M ^a   Rojas, E ^a   Lomonte, B ^a   Gutierrez J M ^a  

^a UNIVERSIDAD DE COSTA RICA   (Costa Rica)

Author keywords

Bothrops asper venom; Polyvalent antivenoms; Snakebite

Indexed keywords

IMMUNOGLOBULIN F(AB')2 FRAGMENT; IMMUNOGLOBULIN G; SNAKE VENOM; VENOM ANTISERUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARTICLE; BLOOD VESSEL INJURY; COMPLEMENT ACTIVATION; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; ENVENOMATION; EXTRAVASATION; IMMUNOGENICITY; IMMUNOGLOBULIN PRODUCTION; LETHALITY; MOUSE; MUSCLE TISSUE; NONHUMAN; PRIORITY JOURNAL; SERUM SICKNESS; TISSUE INJURY;

ANIMALS; ANTIVENINS; BOTHROPS; CROTALID VENOMS; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULIN G; MICE; MUSCLES; NEUTRALIZATION TESTS; SHEEP;

BOTHROPS ASPER; CROTALINAE; EQUIDAE;

EID: 0035188813     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(00)00209-9     Document Type: Article

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