Notch receptor expression in adult human liver: A possible role in bile duct formation and hepatic neovascularization

Hepatology

Volumn 34, Issue 6, 2001, Pages 1184-1192

  Nijjar, Sarbjit S ^a,b   Crosby, Heather A ^a,b   Wallace, Lorraine ^a,b   Hubscher, Stefan G ^a   Strain, Alastair J ^a,b  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b QUEEN ELIZABETH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DNA BINDING PROTEIN; LIGAND; MEMBRANE PROTEIN; MESSENGER RNA; NOTCH RECEPTOR;

ARTICLE; BILE DUCT; CELL INTERACTION; CELL SPECIFICITY; CELL TYPE; GENE EXPRESSION; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LIVER; LIVER CELL; NEOVASCULARIZATION (PATHOLOGY); NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 0035185449     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2001.29399     Document Type: Article

References (36)

1. Notch signaling: Cell fate control and signal integration in development
2. The ins and outs of Notch signaling
3. TAN-1, the human homologue of the Drosophila gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
4. Human homologs of a drosophila enhancer of split gene product define a novel family of nuclear proteins
5. Notch3 mutations in CADASIL, an hereditary adult onset condition causing stroke and dementia
6. Cloning, Characterization, and the complete 56.8-kilobase DNA sequence of the human Notch4 gene
7. Homologs of vertebrate growth factors in Drosophila melanogaster and other invertebrates
8. Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor
9. Mutations in the human Jagged1 gene are responsible for Alagille syndrome
10. Human ligands of the Notch receptor
11. Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis
12. Dll4, a novel Notch ligand expressed in arterial endothelium
13. Lin-12/Notch signaling-Lessons from worms and flies
14. Nuclear access and action of Notch in vivo
15. Strong clustering and stereotyped nature of Notch3 mutations in CADASIL patients
16. The Notch4 locus is associated with susceptibility to schizophrenia
17. Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1
18. JAGGED1 gene expression during human embryogenesis elucidates the wide phenotypic spectrum of alagille syndrome
19. Hepatic jagged-1 expression studies
20. Native and recombinant human hepatocyte growth factors are highly potent promoters of DNA synthesis in both human and rat hepatocytes
21. Immuno-isolation and culture of biliary epithelial cells from normal human liver
22. Human intrahepatic biliary epithelial cells proliferate in vitro in response to human hepatocyte growth factor
23. Xsoxl 7alpha and beta mediate endoderm formation in Xenopus
24. The specification and growth factor inducibility of the pronephric glomus in Xenopus laevis
25. Increased expression of ICAM-1 on bile ducts in primary biliary cirrhosis and primary sclerosing cholangitis
26. The Notch-3 intracellular domain represses Notch-1 mediated activation through Hairy/Enhancer of Split(HES) promoters
27. Notch signaling controls pancreatic cell differentiation
28. Expression of Notch-1, -2 and -3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast fate
29. Characterization and isolation of ductular cells coexpressing neural cell adhesion molecule and Bcl-2 from primary cholangiopathies and ductal plate malformations
30. Cell lineages in hepatic development and the identification of progenitor cells in normal and injured liver
31. Immunolocalisation of putative human liver progenitor cells in livers from patients with end-stage primary biliary cirrhosis and sclerosing cholangitis using the monoclonal antibody OV-6
32. Expression of the stem cell factor receptor c-kit in normal and diseased pediatric liver: Identification of a human hepatic progenitor cell?
33. The scarring of the liver acini (cirrhosis). Tridimensional and microcirculatory considerations
34. Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged-1
35. Maintenance of somite borders in mice requires the Delta homologue Dll1
36. An antisense oligonucleotide to the notch ligand Jagged enhances fibroblast growth factor-induced angiogenesis in vitro