Velo-cardio-facial syndrome: A model for understanding the genetics and pathogenesis of schizophrenia

British Journal of Psychiatry

Volumn 179, Issue NOV., 2001, Pages 397-402

  Murphy, K C ^a   Owen, M J ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MIGRATION; CHROMOSOME 22Q; CHROMOSOME DELETION; DISEASE ASSOCIATION; DISEASE COURSE; GENETIC ANALYSIS; GENETIC DISORDER; HUMAN; MOLECULAR GENETICS; NERVE CELL; NERVE CELL DIFFERENTIATION; NEUROANATOMY; NEUROPSYCHOLOGY; PHENOTYPE; REVIEW; RISK ASSESSMENT; SCHIZOPHRENIA; VELOCARDIOFACIAL SYNDROME;

ABNORMALITIES, MULTIPLE; BRAIN; CHILD; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 22; DEVELOPMENTAL DISABILITIES; FACE; HUMANS; PALATE, SOFT; SCHIZOPHRENIA; SYNDROME;

EID: 0035183495     PISSN: 00071250     EISSN: None     Source Type: Journal    
DOI: 10.1192/bjp.179.5.397     Document Type: Review

References (68)

1. Altered distribution of nicotamide-adenine dinucleotide phosphate-diaphorase cells in frontal lobe of schizophrenics implies disturbances of cortical development
2. Some cytoarchitectural abnormalities of the entorhinal cortex in schizophrenia
3. 22q11 deletion syndrome in adults with schizophrenia
4. Neuropsychology and neurophysiology in schizophrenia
5. Enlarged sylvian fissures in infants with interstitial deletion of chromosome 22q11
6. The neuropsychological signature of schizophrenia: Generalized or differential deficit?
7. Schizophrenia susceptibility loci on chromosomes 13q32 and 8p21
8. Neuropsychological assessment of young people at high genetic risk for developing schizophrenia compared with controls: Preliminary findings of the Edinburgh High Risk Study (EHRS)
9. The schizophrenia high-risk project in Copenhagen: Three decades of progress
10. Qualitative MRI findings in adults with 22q11 deletion syndrome and schizophrenia
11. Craniofacial dysmorphology in schizophrenia
12. Possible role for COMT in psychosis associated with velo-cardio-facial syndrome
13. Children and adolescents with velo-cardio-facial syndrome: A volumetric MRI study
14. Animal models with construct validity for schizophrenia
15. The neuropsychology of schizophrenia: Relations with clinical and neurobiological dimensions
16. Neuropsychological evidence for frontostriatal dysfunction in schizophrenia
17. Early life precursors of psychiatric outcomes in adulthood in subjects at risk for schizophrenia or affective disorders
18. Neuropsychological functioning among the nonpsychotic relatives of schizophrenic patients: A diagnostic efficiency analysis
19. Psychiatric disorders in mental retardation
20. Cognitive and behaviour profile of preschool children with chromosome 22q11.2 deletion
21. The gene encoding proline dehydrogenase modulates sensorimotor gating in mice
22. Velo-cardio-facial syndrome: A review of 120 patients
23. Velo-cardio-facial syndrome: Language and psychological profiles
24. Velocardiofacial manifestations and microdeletions in schizophrenic inpatients
25. Minor physical anomalies in schizophrenia
26. Schizophrenia and its dementia
27. The neuropathology of schizophrenia - A critical review of the data and their interpretation
28. Neuropsychological functioning of first-episode schizophreniform patients
29. Neurocognitive deficit in schizophrenia: A quantitative view of the evidence
30. Prenatal developmental disturbances in the limbic allocortex in schizophrenics
31. Child developmental risk factors for adult schizophrenia in the British 1946 birth cohort
32. Schizophrenia susceptibility associated with interstitial deletions of chromosome 22q11
33. A genome survey of bipolar disorder indicates a susceptibility locus on chromosome 22
34. A genome survey indicates a susceptibility locus for bipolar disorder on chromosome 22: Further support from two additional family sets
35. A neurohistological correlate of schizophrenia
36. Dysmorphic features and schizophrenia
37. The anthropometric assessment of dysmorphic features in schizophrenia as an index of its developmental origins
38. Follow-up report of potential linkage for schizophrenia on chromosome 22q: Part 3
39. Brain abnormality in schizophrenia. A systematic and quantitative review of volumetric magnetic resonance imaging studies
40. Patterning of neural crest derivatives in the avian embryo: In vivo and in vitro studies
41. Clinical correlates of septum pellucidum cavities: An unusual association with psychosis
42. Congenital heart disease in mice deficient for the DiGeorge syndrome region
43. Cerebellar atrophy in a patient with velo-cardio-facial syndrome
44. Cerebellum and schizophrenia: A selective review
45. Brain anomalies in velo-cardio-facial syndrome
46. Characteristic cognitive profile in patients with a22q11.2deletion - Verbal IQ exceeds nonverbal IQ
47. Psychoeducational profile of the 22q11 microdeletion: A complex pattern
48. Schizophrenia CATCH 22 and FISH
49. Minor physical anomalies and their relationship to the aetiology of schizophrenia
50. Chromosome 22q11 deletions. An under-recognised cause of idiopathic learning disability
51. High rates of schizophrenia in adults with velo-cardio-facial syndrome
52. Linkage of a composite inhibitory phenotype to a chromosome 22q locus in eight Utah families
53. Bipolar spectrum disorders in patients diagnosed with velo-cardio-facial syndrome: Does a hemizygous deletion of chromosome 22q11 result in bipolar affective disorder?
54. Psychotic illness in patients diagnosed with velo-cardio-facial syndrome and their relatives
55. Sequential strategy to identify a susceptibility gene for schizophrenia: Report of potential linkage on chromosome q12-q13
56. A combined analysis of D225278 marker alleles in affected sib-pairs: Support for a susceptibility locus for schizophrenia at chromosome 22q12
57. A genome-wide search for schizophrenia susceptibility genes
58. Late-onset psychosis in the velo-cardio-facial syndrome
59. Intelligence and psychological adjustment in velocardiofacial syndrome: A study of 37 children and adolescents with VCFS
60. Neuropsychological, learning and psychosocial profile of primary school aged children with the velo-cardio-facial syndrome (22q11 deletion): Evidence for a non-verbal learning disability?
61. Velocardiofacial syndrome in childhood-onset schizophrenia
62. Structural brain abnormalities associated with deletion of chromosome 22q1 I. Quantitative neuroimaging study of adults with velo-cardio-facial syndrome
63. Midline brain anomalies and schizophrenia in people with CATCH 22 syndrome
64. Meta-analysis of brain and cranial size in schizophrenia
65. A molecular pathway revealing a genetic basis for human cardiac and craniofacial defects