Essential pathogenic role for endogenous interferon-gamma (IFN-γ) during disease onset phase of murine experimental autoimmune orchitis. I. In vivo studies

Clinical and Experimental Immunology

Volumn 111, Issue 3, 1998, Pages 513-520

  Itoh, M ^b   Yano, A ^b   Xie, Q ^b   Iwahashi, K ^b   Takeuchi, Y ^b   Meroni, P L ^a   Nicoletti, F ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b KAGAWA UNIVERSITY   (Japan)

Author keywords

Autoimmunity; In vivo interferon gamma; Testis

Indexed keywords

GAMMA INTERFERON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; DISEASE ACTIVITY; DOWN REGULATION; EXPERIMENTATION; MALE; MOUSE; NONHUMAN; ONSET AGE; ORCHITIS; PRIORITY JOURNAL; TESTIS CELL; TESTIS FUNCTION;

ANIMALS; ANTIBODIES, MONOCLONAL; AUTOIMMUNE DISEASES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; HYPERSENSITIVITY, DELAYED; IMMUNIZATION, PASSIVE; INTERFERON TYPE II; MALE; MICE; MICE, INBRED C3H; ORCHITIS; SPERMATOZOA;

EID: 0031946872     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1998.00527.x     Document Type: Article

References (36)

1. Sato K, Hirokawa K, Hatekeyama S. Experimental allergic orchitis in mice. Histopathological and immunological studies. Virchows Arth [Pathol Anat] 1981; 392:147-58.
2. Itoh M, Hiramine C, Hojo K. A new murine model of autoimmune orchitis induced by immunization with viable syngeneic testicular germ cells alone. I. Immunological and histological studies. Clin Exp Immunol 1991; 83:137-42.
3. Suominen J, Soderstrom KO. Lymphocytic infiltration in human testicular biopsies. Int J Androl 1982; 5:461-6.
4. Tung KSK, Lu CY. Immunologic basis of reproductive failure. In; Kraus FT, Damjanov I, Kaufman N, eds. Pathology of reproductive failure. Baltimore: Williams & Wilkins, 1991; 308-33.
5. Anderson DJ, Hill JA. Cell-mediated immunity in infertility. Am J Reprod Immunol Microbiol 1988; 17:22-30.
6. Pokorna Z, Pekarek J, Svejcar J. The use of an in vitro test of delayed hypersensitivity for the study of experimental autoimmune aspermatogenesis. Folia Biol Praha 1973; 19:187-93.
7. Hojo K, Hiramine C. Suppression of experimental allergic orchitis and cellular immune responses in guinea pig by pretreatment with testis antigen in incomplete Freund's adjuvant. Int Arch Allergy Appl Immunol 1982; 69:40-49.
8. Tung KSK, Menge AC. Sperm and testicular autoimmunity. In: Rose NF, Mackay IR, eds. The autoimmune disease. New York: Academic Press, 1985:537-90.
9. Dijkmans R, Billiau A. Interferon-γ: a master key in the immune system. Curr Opin Immunol 1988; 1:269-74.
10. Vankelecom H, Billiau A. Interferon-γ in neuroimmunology and endocrinology. Adv Neuroimmunol 1992; 2:139-61.
11. Cher DJ, Mossman TR. Two types of murine helper T cell clone II. Delayed-type hypersensitivity is mediated by Th1 clones. J Immunol 1987; 13:3688-94.
12. Martin S, Maruta K, Burkart V et al. IL-1 and IFN-gamma increase vascular permeability. Immunology 1988; 64:301-5.
13. Oppenheimer-Marks N. Ziff M. Migration of lymphocytes through endothelial cell monolayers: augmentation by interferon-gamma. Cell Immunol 1988; 114:307-23.
14. Yu CL, Haskard DO, Cavender D et al. Human gamma interferon increases the binding of T lymphocytes to endothelial cells. Clin Exp Immunol 1985; 62:554-60.
15. Anderson DJ. Cell-mediated immunity and inflammatory processes in male infertility. Archivum Imm et Therap Exp 1990; 38:79-85.
16. Meikle AW, De-Sousa JCC, Dacosta N et al. Direct and indirect effects of murine interleukin-2, gamma interferon, and tumor necrosis factor on testosterone synthesis in mouse Leydig cells. J Androl 1992; 13:437-43.
17. Itoh M, Hiramine C, Tokunaga Y et al. A new murine autoimmune orchitis induced by immunization with viable syngeneic testicular germ cells alone. II. Immunohistochemical findings of fully-developed inflammatory lesion. Autoimmunity 1991; 10:89-97.
18. Itoh M, Mukasa A, Tokunaga Y et al. New experimental model for adoptive transfer of murine autoimmune orchitis. Andrologia 1991; 23:415-20.
19. + regulatory T cells. Clin Immunol Immunopathol 1992; 62: 210-9.
20. Itoh M, Hiramine C, Mukasa A et al. Establishment of an experimental model of autoimmune epididymo-orchitis induced by the transfer of a T cell line in mice. Int J Androl 1992; 15:170-81.
21. Majima T, Hiramine C, Tokunuga Y et al. Murine strain differences in susceptibility to experimental autoimmune orchitis (EAO): variations of cytokine production pattern. Proc. 8th Ann Meet Jap Soc Immunol Reprod 1994; 8:27-31.
22. Itoh M, Hiramine C, Mukasa A et al. Antigen non-specific tissue damage in T cell mediated experimental autoimmune orchitis: preliminary characterization of a testis-specific T cell line by using dermal tissue and cells. Andrologia 1993; 25:89-92.
23. Prat M, Gribaudo G, Comoglio P et al. Monoclonal antibodies against murine gamma interferon. Proc Natl Acad Sci USA 1984; 81:4515-9.
24. Tang H, Mignon-Godefroy K, Meroni PL et al. The effects of a monoclonal antibody to interferon-γ on experimental autoimmune thyroiditis (EAT): prevention of disease and decrease of EAT-specific T cells. Eur J Immunol 1993; 23:275-8.
25. Boissier MC, Chiocchia G, Bessis N et al. Biphasic effect on interferon-γ in murine collagen-induced arthritis. Eur J Immunol 1995; 25:1184-90.
26. Nicoletti F, Zaccone P, Di Marco R et al. The effect of nonimmunogenic form of murine soluble interferon-γ receptor on the development of autoimmune diabetes in the NOD mouse. Endocrinology 1996; 137:5567-75.
27. Itoh M, de-Rooij DG, Takeuchi Y. Mode of inflammatory cell infiltration in testes of mice injected with syngeneic testicular germ cells without adjuvant. J Anat 1995; 187:671-9.
28. + T cell line in mice. Clin Exp Immunol 1992; 87:455-60.
29. Weisenberg I, van der Meide PH, Schellekens H et al. Suppression and augmentation of rat adjuvant arthritis with monoclonal anti-interferon-gamma antibody. Clin Exp Immunol 1989; 78:245-9.
30. Yule TD, Tung KSK. Experimental autoimmune orchitis induced by testis and sperm antigen-specific T cell clones: an important pathogenic cytokine is tumor necrosis factor. Endocrinology 1993; 133:1098-107.
31. Liblau RS, Singer MS, McDevitt HO. Th1 and Th2 cells in the pathogenesis of organ specific autoimmune diseases. Immunol Today 1995; 16:34-38.
32. Nicoletti F, Zaccone P, Marco RD et al. Prevention of spontaneous autoimmune diabetes in diabetes-prone BB rats by prophylactic treatment with anti-rat interferon-γ antibody. Endocrinology 1997; 138:281-8.
33. Youngner JS, Salvin SB. Production and properties of migration inhibitory factor and interferon in the circulation of mice with delayed hypersensitivity. J Immunol 1973; 111:1914-22.
34. Sewell WA, Moerloose PA, McKimm-Breschkin JL et al. Pertussigen enhances antigen-driven interferon-γ production by sensitized lymphoid cells. Cell Immunol 1986; 97:238-47.
35. Itoh M, Chen XH, Takeuchi Y et al. Morphological demonstration of the immune privilege in the testis using adjuvants: tissue responses of male reproductive organs in mice injected with Bordetella pertussigens. Arch Histol Cytol 1995; 58:575-9.
36. Tung KSK, Yule TD, Mahi-Brown C et al. Distribution of histopathology and Ia positive cells in actively induced and passively transferred experimental autoimmune orchitis. J Immunol 1987; 138:752-9.