A new player in the team: SOCS-3 SOCKS it to cytokine signaling in the regenerating liver

Hepatology

Volumn 34, Issue 6, 2001, Pages 1254-1256

  Luedde, Tom ^a   Wuestefeld, Torsten ^a   Trautwein, Christian ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GROWTH FACTOR; INTERLEUKIN 6; JANUS KINASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; STAT PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING; SUPPRESSOR OF CYTOKINE SIGNALING 3; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; CELL CYCLE; DNA BINDING; IMMUNE SYSTEM; KNOCKOUT MOUSE; LIVER CELL; LIVER CELL CARCINOMA; LIVER REGENERATION; MOUSE; NONHUMAN; NOTE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0035180360     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2001.0341254     Document Type: Article

References (11)

1. Liver regeneration
2. Liver regeneration
3. Interleukin 6 and liver regeneration
4. SOCS: Physiological suppressors of cytokine signaling
5. Cytokine signaling: Inhibitors keep cytokines in check
6. Inhibition of signal transducer and activator transcription factor 3 in rats with acute hepatic failure
7. Hyperstimulation with interleukin 6 inhibits cell cycle progression after hepatectomy in mice
8. Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1
9. SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine
10. SOCS3 is essential in the regulation of fetal liver erythropoesis
11. SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity