Pregnancies following high-dose cyclophosphamide with or without high-dose busulfan or total-body irradiation and bone marrow transplantation

Blood

Volumn 87, Issue 7, 1996, Pages 3045-3052

  Sanders, Jean E ^a,b   Hawley, Jennifer ^a   Levy, William ^a   Gooley, Ted ^a   Buckner, C Dean ^a   Deeg, H Joachim ^a   Doney, Kristine ^a   Storb, Rainer ^a   Sullivan, Keith ^a   Witherspoon, Robert ^a   Appelbaum, Frederick R ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUSULFAN; CYCLOPHOSPHAMIDE;

ADULT; ARTICLE; BONE MARROW TRANSPLANTATION; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; DRUG MEGADOSE; FEMALE; FEMALE FERTILITY; HEMATOLOGIC DISEASE; HUMAN; MAJOR CLINICAL STUDY; MALE; OVARY FUNCTION; PREGNANCY; PREGNANCY COMPLICATION; PRIORITY JOURNAL; RISK ASSESSMENT; TESTIS FUNCTION; WHOLE BODY RADIATION;

ADULT; BONE MARROW TRANSPLANTATION; BUSULFAN; CYCLOPHOSPHAMIDE; FEMALE; GRAFT REJECTION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MALE; PREGNANCY; PREGNANCY COMPLICATIONS; PREGNANCY OUTCOME; PRENATAL EXPOSURE DELAYED EFFECTS; WHOLE-BODY IRRADIATION;

EID: 0029930242     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v87.7.3045.bloodjournal8773045     Document Type: Article

References (51)

1. Beatty PG, Anasetti C, Hansen JA, Longton GM, Sanders JE, Martin PJ, Mickelson EM, Choo SY, Petersdorf EW, Pepe MS, Appelbaum FR, Bearman SI, Buckner CD, Clift RA, Petersen FB, Singer J, Stewart PS, Storb RS, Sullivan KM, Tesler MC, Witherspoon RP, Thomas ED: Marrow transplantation from unrelated donors for treatment of hematologic malignancies: Effect of mismatching for one HLA locus. Blood 81:249, 1993
2. Kernan NA, Bartsch G, Ash RC, Beatty PG, Champlin R, Filipovich A, Gajewski J, Hansen JA, Henslee-Downey J, McCullough J, McGlave P, Perkins HA, Phillips GL, Sanders J, Stroncek D, Thomas ED, Blume KG: Analysis of 462 transplantations from unrelated donors facilitated by The National Marrow Donor Program. N Engl J Med 328:593, 1993
3. Seeger RC, Vo DD, Ugelstad, Reynolds CP: Removal of neuroblastoma cells from bone marrow with monoclonal antibodies and magnetic immunobeads. Prog Clin Biol Res 211:285, 1986
4. Krivit W, Shapiro EG: Bone marrow transplantation for storage diseases, in Desnick RJ (ed): Treatment of Genetic Disease. New York, NY, Churchill-Livingstone, 1991
5. Peters WP, Shpall EJ, Jones RB, Olsen GA, Bast RC, Gockerman JP, Moore JO: High-dose combination alkylating agents with bone marrow support as initial treatment for metastatic breast cancer. J Clin Oncol 6:1368, 1988
6. Damewood MD, Grochow LB: Prospects for fertility after chemotherapy or radiation for neoplastic disease. Fertil Steril 45:443, 1986
7. Caligiuri MA, Mayer RJ: Pregnancy and leukemia. Semin Oncol 16:388, 1989
8. Byrne J, Mulvihill JJ, Myers MH, Connelly RR, Naughton MD, Krauss MR, Steinhorn SC, Hassinger DD, Austin DF, Bragg K, Holmes GF, Holmes FF, Latourette HB, Weyer PJ, Meigs JW, Teta MJ, Cook JW, Strong LC: Effects of treatment on fertility in long-term survivors of childhood or adolescent cancer. N Engl J Med 317:1315, 1987
9. Aisner J, Wiernik PH, Pearl P: Pregnancy outcome in patients treated for Hodgkin's disease. J Clin Oncol 11:507, 1993
10. Mulvihill JJ: Sentinel and other mutational effects in offspring of cancer survivors. Prog Clin Biol Res 340C:179, 1990
11. Green DM, Hall B, Zevon MA: Pregnancy outcome after treatment for acute lymphoblastic leukemia during childhood or adolescence. Cancer 64:2335, 1989
12. Green DM, Zevon MA, Lowrie G, Seigelstein N, Hall B: Congenital anomalies in children of patients who received chemotherapy for cancer in childhood and adolescence. N Engl J Med 325:141, 1991
13. Li FP, Gimbrere K, Gelber RD, Sallan SE, Flamant F, Green DM, Heyn RM, Meadows AT: Outcome of pregnancy in survivors of Wilms' tumor. JAMA 257:216, 1987
14. Hawkins MM, Smith RA: Pregnancy outcomes in childhood cancer survivors: Probable effects of abdominal irradiation. Int J Cancer 43:399, 1989
15. Garber JE, Lynch EA, Meadows AT, Green DM, Tarbell NJ, Li FP: Pregnancy outcome after therapy of childhood cancer. Proc Am Soc Clin Oncol 9:290, 1990 (abstr)
16. Card RT, Holmes IH, Sugarman RG, Storb R, Thomas ED: Successful pregnancy after high dose chemotherapy and marrow transplantation for treatment of aplastic anemia. Exp Hematol 8:57, 1980
17. Jacobs P, Dubovsky DW: Bone marrow transplantation followed by normal pregnancy. Am J Hematol 11:209, 1981
18. Deeg HJ, Kennedy MS, Sanders JE, Thomas ED, Storb R: Successful pregnancy after marrow transplantation for severe aplastic anemia and immunosuppression with cyclosporine. JAMA 250:647, 1983
19. Schmidt H, Ehninger G, Dopfer R, Waller HD: Pregnancy after bone marrow transplantation for severe aplastic anemia. Bone Marrow Transplant 2:329, 1987
20. Sanders JE, Buckner CD, Amos D, Levy W, Appelbaum FR, Doney K, Storb R, Sullivan KM, Witherspoon RP, Thomas ED: Ovarian function following marrow transplantation for aplastic anemia or leukemia. J Clin Oncol 6:813, 1988
21. Buskard N, Ballem P, Hill R, Fryer C: Normal fertility after total body irradiation and chemotherapy in conjunction with a bone marrow transplantation for acute leukemia. Fifteenth Annual Meeting of the European Group for Blood and Bone Marrow Transplantation (EBMT), Badgastein, Austria, February 26-March 2, 1989 (abstr)
22. Russel JA, Hanley DA: Full-term pregnancy after allogeneic transplantation for leukemia in a patient with oligomenorrhea. Bone Marrow Transplant 4:579, 1989
23. Milliken S, Powles R, Parikh P, Whitehead M, Mayes I, Prentice A, Falconer A, Aboud H, Helenglass G, Nandi A, Talbot D, Treleaven J: Successful pregnancy following bone marrow transplantation for leukaemia. Bone Marrow Transplant 5:135, 1990
24. Calmard-Oriol P, Dauriac C, Vu Van H, Lacroze M, Landriot B, Guyotat D: Successful pregnancy following allogeneic bone marrow transplantation after conditioning by thoraco-abdominal irradiation. Bone Marrow Transplant 8:229, 1991
25. Hinterberger-Fischer M, Kier P, Kalhs P, Marosi C, Geissler K, Schwarzinger I, Pabinger I, Huber J, Kolbabek H, Koren H, Müller G, Hawliczek R, Lechner K, Hayek-Rosenmayr A, Hinterberger W: Fertility, pregnancies and offspring complications after bone marrow transplantation. Bone Marrow Transplant 7:5, 1991
26. Giri N, Vowels MR, Barr AL, Mameghan H: Successful pregnancy after total body irradiation and bone marrow transplantation for acute leukaemia. Bone Marrow Transplant 10:93, 1992
27. Lipton JH, Derzko C, Fyles G, Meharchand J, Messner HA: Pregnancy after BMT: Three case reports. Bone Marrow Transplant 11:415, 1993
28. Storb R, Longton G, Anasetti C, Appelbaum FR, Beatty P, Bensinger W, Crawford S, Deeg HJ, Doney K, Fefer A, Hansen J, Loughran T, Martin P, Pepe M, Petersen FB, Sanders JE, Singer J, Stewart P, Sullivan KM, Thomas ED, Witherspoon RP: Changing trends in marrow transplantation for aplastic anemia. Bone Marrow Transplant 10:45, 1992 (suppl I)
29. Clift RA, Buckner CD, Thomas ED, Kopecky KJ, Appelbaum FR, Tallman M, Storb R, Sanders J, Sullivan K, Banaji M, Beatty PS, Bensinger W, Cheever M, Deeg J, Doney K, Fefer A, Greenberg P, Hansen JA, Hackman R, Hill R, Martin P, Meyers J, McGuffin R, Neiman P, Sale G, Shulman H, Singer J, Stewart P, Weiden P, Witherspoon R: The treatment of acute non-lymphoblastic leukemia by allogeneic marrow transplantation. Bone Marrow Transplant 2:243, 1987
30. Doney K, Fisher LD, Appelbaum FR, Buckner CD, Storb R, Singer J, Fefer A, Anasetti C, Beatty P, Bensinger W, Clift R, Hansen J, Hill R, Loughran TP Jr, Martin P, Petersen FB, Sanders J, Sullivan KM, Stewart P, Weiden P, Witherspoon R, Thomas ED: Treatment of adult acute lymphoblastic leukemia with allogeneic bone marrow transplantation. Multivariate analysis of factors affecting acute graft-versus-host disease, relapse, and relapse-free survival. Bone Marrow Transplant 7:453, 1991
31. Clift RA, Buckner CD, Thomas ED, Bensinger WI, Bowden R, Bryant E, Deeg HJ, Doney KC, Fisher LD, Hansen JA, Martin P, McDonald GB, Sanders JE, Schoch G, Singer J, Storb R, Sullivan KM, Witherspoon RP, Appelbaum FR: Marrow transplantation for chronic myeloid leukemia: A randomized study comparing cyclophosphamide and total body irradiation with busulfan and cyclophosphamide. Blood 84:2036, 1994
32. Petersen FB, Appelbaum FR, Hill R, Fisher LD, Bigelow CL, Sanders JE, Sullivan KM, Bensinger WI, Witherspoon RP, Storb R, Clift RA, Fefer A, Press OW, Weiden PL, Singer J, Thomas ED, Buckner CD: Autologous marrow transplantation for malignant lymphoma. A report of 101 cases from Seattle. J Clin Oncol 8:638, 1990
33. Thomas ED, Storb R, Clift RA, Fefer A, Johnson FL, Neiman PE, Lerner KG, Glucksberg H, Buckner CD: Bone-marrow transplantation. N Engl J Med 292:832, 1975
34. Storb R, Deeg HJ, Farewell V, Doney K, Appelbaum F, Beatty P, Bensinger W, Buckner CD, Clift R, Hansen J, Hill R, Longton G, Lum L, Martin P, McGuftin R, Sanders J, Singer J, Stewart P, Sullivan K, Witherspoon R, Thomas ED: Marrow transplantation for severe aplastic anemia: Methotrexate alone compared with a combination of methotrexate and cyclosporine for prevention of acute graft-versus-host disease. Blood 68:119, 1986
35. Sullivan KM, Witherspoon RP, Storb R, Weiden P, Flournoy N, Dahlberg S, Deeg HJ, Sanders JE, Doney KC, Appelbaum FR, McGuffin R, McDonald GB, Meyers J, Schubert MM, Gauvreau J, Shulman HM, Sale GE, Anasetti C, Loughran TP, Strom S, Nims J, Thomas ED: Prednisone and azathioprine compared with prednisone and placebo for treatment of chronic graft-versus-host disease: Prognostic influence of prolonged thrombocytopenia after allogeneic marrow transplantation. Blood 72:546, 1988
36. Stickle G: Defective development and reproductive wastage in the United States. Am J Obstet Gynecol 100:442, 1968
37. Wilcox AJ, Weinberg CR, O'Connor JF, Baird DD, Schlatterer JP, Canfield RE, Armstrong EG, Nisula BC: Incidence of early loss of pregnancy. N Engl J Med 319:189, 1988
38. Creasy RK: Preterm labor and delivery, in Creasy RK, Resnik R (eds): Maternal-Fetal Medicine, Principles and Practice (ed 2). Philadelphia, PA, Saunders, 1989, p 477
39. Behrman RE, Shiono PH: Neonatal risk factors, in Fanaroff AA, Martin RJ (eds): Neonatal-Perinatal Medicine - Disease of the Fetus and Infants (ed 5). St Louis, MO, Mosby-Year Book, 1992, p 3
40. Marden PM, Smith DW, McDonald MJ: Congenital anomalies in the newborn infant, including minor variations. J Pediatr 64:357, 1964
41. Sanders JE, and the Seattle Marrow Transplant Team: The impact of marrow transplant preparative regimens on subsequent growth and development. Semin Hematol 28:244, 1991
42. Ortin TTS, Shostak CA, Donaldson SS: The Stanford gonadal status and reproductive function following treatment for Hodgkin's disease in childhood: The Stanford experience. Int J Radiat Oncol Biol Phys 19:873, 1990
43. Wilcox AJ, Horney LF: Accuracy of spontaneous abortion recall. Am J Epidemiol 120:727, 1984
44. Hopewell JW: The importance of vascular damage in the development of late radiation effects in normal tissues, in Meyn RE, Withers HR (eds): Radiation Biology in Cancer Research. New York, NY, Raven, 1980, p 449
45. Critchley HOD, Wallace WHB, Shalet SM, Mamtora H, Higginson Y, Anderson DC: Abdominal irradiation in childhood: The potential for pregnancy. Br J Obstet Gynaecol 99:392, 1992
46. Shulman HM, Sale GE, Lerner KG, Barker EA, Weiden PL, Sullivan K, Gallucci B, Thomas ED, Storb R: Chronic cutaneous graft-versus-host disease in man. Am J Pathol 91:545, 1978
47. Schubert MA, Sullivan KM, Schubert MM, Nims J, Hansen M, Sanders JE, O'Quigley J, Witherspoon RP, Buckner CD, Storb R, Thomas ED: Gynecological abnormalities following allogeneic bone marrow transplantation. Bone Marrow Transplant 5:425, 1990
48. Neel JV, Satoh C, Goriki K, Asakawa J, Fujita M, Takahashi N, Kageoka T, Hazama R: Search for mutations altering protein charge and/or function in children of atomic bomb survivors: Final report. Am J Hum Genet 42:663, 1988
49. Albertini RJ: Somatic gene mutations in vivo as indicated by the 6-thioguanine-resistant T-lymphocytes in human blood. Mutat Res 150:411, 1985
50. Hakoda M, Akiyama M, Kyoizumi S, Ava AA, Yamakido M, Otake N: Increased somatic mutant frequency in atomic bomb survivors. Mutat Res 201:39, 1988
51. Kyoizumi S, Nakamura N, Hakoda M, Awa AA, Bean MA, Jensen RH: Detection of somatic mutations at the glycophorin A locus in erythrocytes of atomic bomb survivors using a single beam flow sorter. Cancer Res 49:581, 1989